Which of the following is NOT an event that can result in an autoimmune disease? Which of the following is NOT an event that can result in an autoimmune disease? binding of a T cell to an antigen without receiving a co-stimulatory signal activation of self-reactive lymphocytes that survived negative selection genetic mutations causing changes in the structure of self-antigens cross-reaction of antibodies produced against foreign antigens with self-antigens

Which of the following is NOT an event that can result in an autoimmune disease? Which of the following is NOT an event that can result in an autoimmune disease? binding of a T cell to an antigen without receiving a co-stimulatory signal activation of self-reactive lymphocytes that survived negative selection genetic mutations causing changes in the structure of self-antigens cross-reaction of antibodies produced against foreign antigens with self-antigens

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)

10th Edition

ISBN:9781305967359

Author:STARR

Publisher:STARR

Chapter34: Immunity

Section: Chapter Questions

Problem 3SA: Which of the following is not a part of innate immunity? a. phagocytic cells e. inflammation b....

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Which of the following is not a part of innate immunity? a. phagocytic cells e. inflammation b. fever f. complement activation c. histamines g. presenting antigen d. cytokines h. all take part
Which of the following is part of the T-cell clonal deletion process? a) T-cells are eliminated if they bind to B-cells b) Lymphocytes that bind to MHC undergo apoptosis c) T-cells that bind to the same antigen as B-cells are eliminated d) Lymphocytes that react to autoantigens unde
Of the following, which should NOT occur in order to facilitate T-cell selection in the thymus? A) positive-selection based on an interaction with MHC alone B) negative-selection based on a failed interaction with self-peptides in a MHC C) apoptosis of T-cells that fail to interact with MHC alone during positive selection. D) negative-selection based on an interaction with MHC containing a non-self peptide
All of the following are characteristic of regulatory T cells except a. they express CD25 b. they facilitate the proliferation of naive T cells interacting with the same antigen-presenting cell c. they express CD4 d. they express the transcriptional repressor FoxP3 e. they express MHC class II-restricted T-cell receptors specific for self antigen.
What is the difference between memory T cells and cytotoxic T cells? Memory T cells need more regulatory cell interactions to become active. Cytotoxic T cells live longer. Memory T cells do not need to interact with antigen-presenting cells to become activated. More cytotoxic T cells than memory T cells are activated during a second exposure to an antigen.
Which of the following is NOT true about T cells? A. Natural killer cells (NK) are exclusively differentiated T cells B. T cells act in situations where antigens are embedded in cell membranes or are inside host cells and thus are inaccessible to antibodies C. T cells develop from lymphoid stem cells in bone marrow and mature in the thymus D. Cell-mediated immunity is primarily carried out by T cells
Which of the following is NOT one of the major functions of T lymphocytes (T cells)? activating the immune system binding to antigens presented by MHC proteins production of antibodies forming memory cells to more rapidly respond to future infections by the same pathogen attacking our own cells that are infected with a virus or cancerous
What occurs in a cell-mediated immune response? Select all that apply. Naive B cells bind to antigen on the surface of a bacterium and become activated. A dendritic cell incorporates digested viral antigen-MHC complexes. Naive cytotoxic T cells bind to antigen on antigen-presenting dendritic cells and become activated. Effector cytotoxic T cells circulate through the body and kill any body cells that display the viral antigen-MHC complexes.
In which of the following ways are T-cell receptors distinct from immunoglobulins? (Select all that apply.) a. T-cell receptors are generated through somatic recombination. b. The T-cell repertoire encompasses a very large degree of diversity. c. T-cell receptors are never secreted subsequent to antigen encounter. d. The variable region of T-cell receptors contains complementarity-determining regions that interact with antigen. e. T-cell receptors are used solely for the purpose of antigen recognition and not for effector function.
Which of the following is NOT true of Innate Lymphoid Cells (ILCs)? A) Each ILC type responds to a different category of pathogens. b.)) ILCs are derived from the common lymphoid precursor. c. )) ILCs rearrange their antigen receptors in a similar way to T-cells. d. ))Each ILC type is distinguished by the cytokines that it produces. e. ))Development of each ILC type is driven by unique transcription factors.
Which of the following statements about T cells is false? a. Helper T cells release cytokines while cytotoxic T cells kill the infected cell. b. Helper T cells are CD4+, while cytotoxic T cells are CD8+. c. MHC II is a receptor found on most body cells, while MHC I is a receptor found on immune cells only. d. The T cell receptor is found on both CD4+ and CD8+ T cells.
Which of the following explains why dendritic cells, but not macrophages or B cells, contribute to the activation of naive T cells? a. Macrophages and B cells do not express MHC class II molecules until they are activated. b. Dendritic cells upregulate B7 after engaging innate immunity receptors at sites of infection. c. Dendritic cells express higher levels of CTLA4. d. Macrophages and B cells do not process antigen. e. Dendritic cells use Toll-like receptors to hold antigen in place for extended periods of time.