Which of the following statements is the most accurate concerning lymphocytes? a. T cells and B cells both express TCRs. These are the product of approximately 100 genes. Each lymphocyte expresses only one of the ~100 receptors coded for by these genes, and in the absence of clonal selection the liklihood that two cells express the same receptor is only moderate b. T cells and B cells express TCRs and BCRs respectively. These are the product of genetic recombination and can comprise one of millions of combinations. Each lymphocyte can express 1000s of different receptor variants, maximizing the likelihood that a single adaptive immune cell will recognize pathogen-associated antigens. c. T cells and B cells express TCRs and BCRs respectively. These are the product of genetic recombination and can comprise one of millions of combinations. Each lymphocyte expresses only one of these receptors, and in the absence of clonal selection the liklihood that two cells express the same receptor is exteremely low. d. T cells and B cells express TCRs and BCRs respectively. TCRs directly bind to MHC-I facilitating destruction of abhorrent cells by T-lymphocytes. In contrast, BCRs bind MHC II, allowing B cells to destroy MHC II-expressing pathogens.

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Which of the following statements is the most accurate concerning lymphocytes? a. T cells and B cells both express TCRs. These are the product of approximately 100 genes. Each lymphocyte expresses only one of the ~100 receptors coded for by these genes, and in the absence of clonal selection the liklihood that two cells express the same receptor is only moderate b. T cells and B cells express TCRs and BCRs respectively. These are the product of genetic recombination and can comprise one of millions of combinations. Each lymphocyte can express 1000s of different receptor variants, maximizing the likelihood that a single adaptive immune cell will recognize pathogen-associated antigens. c. T cells and B cells express TCRs and BCRs respectively. These are the product of genetic recombination and can comprise one of millions of combinations. Each lymphocyte expresses only one of these receptors, and in the absence of clonal selection the liklihood that two cells express the same receptor is exteremely low. d. T cells and B cells express TCRs and BCRs respectively. TCRs directly bind to MHC-I facilitating destruction of abhorrent cells by T-lymphocytes. In contrast, BCRs bind MHC II, allowing B cells to destroy MHC II-expressing pathogens.

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