Which of the following is true about complement? Check all that apply. Three pathways of complement, where classical and alternative, are activated by antibodies and lectin by spontaneous hydrolysis of C3 Complement pathways are activated in response to infections and involved in opsonization, phagocytosis and lysis of microbes The"b" subunit of complement such as C3b or C5b is deposited on the microbes, whereas the "a" subunit, C3a or C5a recruits phagocytic cells to the site of infection and promotes inflammation Alternative pathway is activated immediately due to presence of C3b because of spontaneous hydrolysis of C3, whereas classical pathways in several days after secretion of pathogen-specific antibodies Seven complement(C) proteins are made by liver and C5 is found in abundance
Which of the following is true about complement? Check all that apply.
Three pathways of complement, where classical and alternative, are activated by antibodies and lectin by spontaneous hydrolysis of C3
Complement pathways are activated in response to infections and involved in opsonization, phagocytosis and lysis of microbes
The"b" subunit of complement such as C3b or C5b is deposited on the microbes, whereas the "a" subunit, C3a or C5a recruits phagocytic cells to the site of infection and promotes inflammation
Alternative pathway is activated immediately due to presence of C3b because of spontaneous hydrolysis of C3, whereas classical pathways in several days after secretion of pathogen-specific antibodies
Seven complement(C) proteins are made by liver and C5 is found in abundance
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