Which of the following is true about formation of the secondary structure features, a-helices or a B- sheets? Their formations are enthalpically favored because they are largely stabilized by H-bonding Their formation is entropically unfavored because their formation restricts the rotational and translational motion of the constituent amino acids O Their formation is entropically favored because of the hydrophobic effect

Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter3: The Chemistry Of Life: Organic Compounds
Section: Chapter Questions
Problem 9TYU: Which of the following levels of protein structure may be affected by hydrogen bonding? (a) primary...
icon
Related questions
icon
Concept explainers
Question

Show your all calculation

Which of the following is true about formation of the secondary structure features, a-helices or a B-
sheets?
Their formations are enthalpically favored because they are largely stabilized by H-bonding
Their formation is entropically unfavored because their formation restricts the rotational and translational motion
of the constituent amino acids
O Their formation is entropically favored because of the hydrophobic effect
Transcribed Image Text:Which of the following is true about formation of the secondary structure features, a-helices or a B- sheets? Their formations are enthalpically favored because they are largely stabilized by H-bonding Their formation is entropically unfavored because their formation restricts the rotational and translational motion of the constituent amino acids O Their formation is entropically favored because of the hydrophobic effect
Expert Solution
Step 1

The secondary structure of protein forms by the hydrogen-bonding interactions between the amino acid residues.

Step 2

For a spontaneous process, the change in Gibbs free energy must be negative.

G=H-TS

A process having an overall negative Gibbs free energy is spontaneous.

During the formation of secondary structure of proteins, hydrogen bonding interactions occur between the amino acid residues. These interactions are stabilizing and releases energy, or H=-ve

But since the rotations are restricted, entropy is also decreased. For an entropy driven process, the entropy must increase, thus the process of formation of secondary structure of proteins is not entropy favored.

So here, S=-ve, or TS=-ve, or -TS=+ve

Hydrophobic effect occurs during the formation of tertiary structure of proteins.

steps

Step by step

Solved in 3 steps

Blurred answer
Knowledge Booster
Tissue system
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biology (MindTap Course List)
Biology (MindTap Course List)
Biology
ISBN:
9781337392938
Author:
Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:
Cengage Learning
Human Heredity: Principles and Issues (MindTap Co…
Human Heredity: Principles and Issues (MindTap Co…
Biology
ISBN:
9781305251052
Author:
Michael Cummings
Publisher:
Cengage Learning