Which of the following statements about "Focused transcription initiation", "Dispersed transcription initiation" and "transcription start sites" (TSS) are correct.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Topic Video
Question
Which of the following statements
about "Focused transcription
initiation", "Dispersed transcription
initiation" and "transcription start sites"
(TSS) are correct.
Note: it's more than 1!
The majority of human genes is
regulated from dispersed promoters.
Focused initiation starts form a single or
narrow set of transcription start sites
(TSSS).
Focused and dispersed transcription
initiation refer to the extreme ends of a
continuum of initiation patterns.
Dispersed transcription initiation is the
evolutionary more ancient mechanism.
RNA-seq is the preferred method to
map TSS.
Although dispersed promoter start from
multiple TSS, the resulting transcripts
usually encode for the same protein.
Transcribed Image Text:Which of the following statements about "Focused transcription initiation", "Dispersed transcription initiation" and "transcription start sites" (TSS) are correct. Note: it's more than 1! The majority of human genes is regulated from dispersed promoters. Focused initiation starts form a single or narrow set of transcription start sites (TSSS). Focused and dispersed transcription initiation refer to the extreme ends of a continuum of initiation patterns. Dispersed transcription initiation is the evolutionary more ancient mechanism. RNA-seq is the preferred method to map TSS. Although dispersed promoter start from multiple TSS, the resulting transcripts usually encode for the same protein.
Which of the following statements
about "Focused transcription
initiation", "Dispersed transcription
initiation" and "transcription start sites"
(TSS) are correct.
Note: it's more than 1!
The majority of human genes is
regulated from dispersed promoters.
Focused initiation starts form a single or
narrow set of transcription start sites
(TSSS).
Focused and dispersed transcription
initiation refer to the extreme ends of a
continuum of initiation patterns.
O Dispersed transcription initiation is the
evolutionary more ancient mechanism.
RNA-seq is the preferred method to
map TSS.
Although dispersed promoter start from
multiple TSS, the resulting transcripts
usually encode for the same protein.
Transcribed Image Text:Which of the following statements about "Focused transcription initiation", "Dispersed transcription initiation" and "transcription start sites" (TSS) are correct. Note: it's more than 1! The majority of human genes is regulated from dispersed promoters. Focused initiation starts form a single or narrow set of transcription start sites (TSSS). Focused and dispersed transcription initiation refer to the extreme ends of a continuum of initiation patterns. O Dispersed transcription initiation is the evolutionary more ancient mechanism. RNA-seq is the preferred method to map TSS. Although dispersed promoter start from multiple TSS, the resulting transcripts usually encode for the same protein.
Expert Solution
Step 1: What is transcription ?

Transcription is the process by which the DNA sequence is "transcribed" into RNA sequence. It is the first step in gene regulation. Protein is what gives living organisms its form. The DNA has a lot of material, of which genes are a small part. These genes or protein coding regions alone are copied into RNA, which is then translated into proteins.

RNAs are of many types. mRNA or messenger RNA is the RNA, as the name suggests, carries the protein coding information from the DNA to the proteins.

Transcription involves the following steps:

  1. Initiation: Unwinding of DNA and binding of the RNA polymerase to the promoter
  2. Elongation: The RNA polymerase moves forwards generating the RNA strand
  3. Termination: This step varies between prokaryotes and eukaryotes. In eukaryotes, there is an additional step of adding a polyA tail
  4. Post transcriptional modifications: This includes splicing out the introns, addition of 5' G-cap

 

steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Gene expression
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education