Which of these statements regarding the affected gene are likely to be TRUE? Both copies of the gene will have to be mutated for disease to occur The mutated gene is a tumour suppressor gene The mutations in this gene are passenger mutations The mutations are probably caused by a large deletion The mutation has to be in the coding region Only one of the mutated copies of this gene have to be inherited to increase the tumour risk The mutated gene is an oncogene 09:10

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter19: Genomes And Proteomes
Section: Chapter Questions
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10. Point mutations in a particular region of chromosome 9 were found to be associated with the occurance of a rare rhabdomyosarcoma in members of an extended family.
Which of these statements regarding the affected gene are likely to be TRUE?
Both copies of the gene will have to be mutated for disease to occur
The mutated gene is a tumour suppressor gene
The mutations in this gene are passenger mutations
The mutations are probably caused by a large deletion
The mutation has to be in the coding region
Only one of the mutated copies of this gene have to be inherited to increase the tumour risk
The mutated gene is an oncogene
09:10
2022
Transcribed Image Text:10. Point mutations in a particular region of chromosome 9 were found to be associated with the occurance of a rare rhabdomyosarcoma in members of an extended family. Which of these statements regarding the affected gene are likely to be TRUE? Both copies of the gene will have to be mutated for disease to occur The mutated gene is a tumour suppressor gene The mutations in this gene are passenger mutations The mutations are probably caused by a large deletion The mutation has to be in the coding region Only one of the mutated copies of this gene have to be inherited to increase the tumour risk The mutated gene is an oncogene 09:10 2022
13. The tumour tolerance of CTVT can be broken by inflammation associated with vincristine treatment. In this context, what is meant by 'tumour tolerance'?
Tumour cells are tolerated by the immune system.
Tumour cells are tolerant to chemotherapy.
Tumour cells are tolerant to targeted therapy.
Patients' healthy are tolerant to chemotherapy.
Patients' healthy are tolerant to targeted therapy.
Tumours are tolerated by the vasculature.
Transcribed Image Text:13. The tumour tolerance of CTVT can be broken by inflammation associated with vincristine treatment. In this context, what is meant by 'tumour tolerance'? Tumour cells are tolerated by the immune system. Tumour cells are tolerant to chemotherapy. Tumour cells are tolerant to targeted therapy. Patients' healthy are tolerant to chemotherapy. Patients' healthy are tolerant to targeted therapy. Tumours are tolerated by the vasculature.
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