Which would be the best way to carry out the following synthesis? OH A (1) t-BUOK, (2) BH3 THF, (3) H202/N2OH/H20 B) (1) t-BUOK, (2) H30* (c) (1) NaOCH3, (2) H3O* D NaOH/ H20

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter22: Reactions Of Benzene And Its Derivatives
Section: Chapter Questions
Problem 22.50P: Following is the structure of miconazole, the active antifungal agent in a number of...
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Organic Chemistry Questions:
Which would be the best way to carry out the
following synthesis?
(А) (1) t-BuOK, (2) ВНз-ТHF, (3) Н,02/NaOH/H,0
в) (1) t-BuOK, (2) Нз0*
с) (1) NaOCH3, (2) Нз0*
D NaOH/ H20
What is the main difference between an aromatic
and antiaromatic compound?
Aromatic compounds must satisfy Hückel's
rule.
Aromatic compounds must be cyclic and
B
planar, but not antiaromatic compounds.
Antiaromatic compounds must have a
c) conjugated system with a p orbital at every
vertex.
D) Aromatic compounds must be monocyclic.
This substituent deactivates the benzene ring
towards electrophilic substitution but directs the
incoming group chiefly to the ortho and para
positions.
A) -NHCOCH3
B -NO2
C -OCH2CH3
D) -Br
O O © O
Transcribed Image Text:Which would be the best way to carry out the following synthesis? (А) (1) t-BuOK, (2) ВНз-ТHF, (3) Н,02/NaOH/H,0 в) (1) t-BuOK, (2) Нз0* с) (1) NaOCH3, (2) Нз0* D NaOH/ H20 What is the main difference between an aromatic and antiaromatic compound? Aromatic compounds must satisfy Hückel's rule. Aromatic compounds must be cyclic and B planar, but not antiaromatic compounds. Antiaromatic compounds must have a c) conjugated system with a p orbital at every vertex. D) Aromatic compounds must be monocyclic. This substituent deactivates the benzene ring towards electrophilic substitution but directs the incoming group chiefly to the ortho and para positions. A) -NHCOCH3 B -NO2 C -OCH2CH3 D) -Br O O © O
Which reaction can accomplish the following
transformation in good yield?
OH
+ en
A
oxidative hydroboration
base-catalyzed hydration
oxymercuration/ demercuration
D acid-catalyzed hydration
Predict the product(s) for the following reaction.
excess HI
heat
A
iodobenzene + ethanol
B) ethanol + phenol
phenol + iodoethane
iodobenzene + iodoethane
Transcribed Image Text:Which reaction can accomplish the following transformation in good yield? OH + en A oxidative hydroboration base-catalyzed hydration oxymercuration/ demercuration D acid-catalyzed hydration Predict the product(s) for the following reaction. excess HI heat A iodobenzene + ethanol B) ethanol + phenol phenol + iodoethane iodobenzene + iodoethane
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