why are the second or third enzymes in a reaction sequence not used as regulatory enzymes?

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter6: Metabolism
Section: Chapter Questions
Problem 23CTQ: With regard to enzymes, why are vitamins necessary for good health? Give examples.
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28/ why are the second or third enzymes in a reaction sequence not used as regulatory enzymes?
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