Why are there no Pol I mutants that completely lack 5′ → 3′ exonucleaseactivity?

Q: What is the purpose of DNA methylation? Why is it ineffective in the DNA repair of spontaneous…

A: DNA methylation is the process of adding methyl groups to DNA at Nucleotide bases, so that without…

Q: What is a non replicative conservative transposon?

A: Transposons are the DNA segment that is known to move from one location to another within a genome.…

Q: What are the best available databases for identification of alternatively spliced isoforms in human…

A: Genome sequencing means to determine the whole DNA sequence of the particular organism like the…

Q: What is the difference between nonhomologous end-joining (NHEJ) and homology-directed repair (HDR)…

A: Genome editing can be defined as the way of of making  the specific changes to the DNA of a cell or…

Q: What is the primary difference between a composite transposon and a simple transposon?

A: Transposons are the DNA sequences capable of changing its position or location within the genome of…

Q: What Are the Rules in Codon–AnticodonPairing?

A: The tRNA carries out the amino acids to the mRNA in a specific order which was determined by the…

Q: What are deletion mutation with suitable example?

A: Mutations are the alterations or the changes that occur in the DNA. Mutations are variations in…

Q: If circular B-DNA is positively supercoiled, will these supercoils be left- or right-handed?

A: Supercoiling of DNA is a biological process that regulated the unwinding and rewinding of the DNA…

Q: What is the difference between a transition and a transversion? Which type of base substitution is…

A: There are two different types of mutations with DNA substitutions seen in nature.  These are of two…

Q: What is the reason that eukaryotic cells require telomerase, but bacterial cells do not?

A: Telomerase is also known as a terminal transferase. it is a ribonucleoprotein that is required to…

Q: Why can't the RNA leader form the terminator in the 2-3 stem loop configuration and what happens as…

A: The question is the part of the tryptophan operon and attenuation.  Attenuation is a mechanism for…

Q: Why transposons are called jumping genes?

A: A sequence of DNA sequence that has the ability to move or insert itself at a new location in the…

Q: What is the Evidence for a triplet code?

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Why did we obtain the sequence from the forward primers separate from the reverse primer?

A: Deoxyribonucleic acid (DNA) is a hereditary molecule that passes genetic information from one…

Q: Why do trans-sRNAs often require a chaperone protein?

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Why is Fnu4HI useful for determining which polymorphism is present at codon 49 (SNP rs713598) and…

A: TAS2R38 gene is large family of taste receptor gene encoding protein T2R38 a g protein coupled…

Q: What is an anomer? Are these two models anomers? Explain.

A: Stereoisomerism or spatial isomerism is a form of isomerism in which molecules have the same…

Q: How do these engineered nucleases effect a change in the genomic DNA sequence?

A: Genome editing is a technique used to precisely and efficiently modify DNA within a cell. It…

Q: What is the major form of DNA methylation that is seen in eukaryotes? At what type of DNA sequence…

A: Step 1 Deoxyribonucleic acid (DNA) methylation is am epigenetic procedure that takes place by adding…

Q: What mutagen causes thymine dimers, and why does it kill cells?

A: A mutation occurs/happens when the sequence/structure of DNA changes. Mutations can occur/happens as…

Q: Why is the trp attenuation mechanism unique to prokaryotes?

A: Attenuation is a control mechanism that operates to regulate the expression of genes of an operon.…

Q: Why are transposable elements often called genomic parasites?

A: Transposable elements, also known as jumping genes are short segments of DNA, which have special…

Q: What is reverse transcription simple definition?

A: The process by which generation of new proteins in a cell takes place is known as protein synthesis.…

Q: What would be the phenotype of an E. coli strain in which the tandem tryptophan codons in the leader…

A: The set of genes controlled by a single promoter or regulatory sequence associated with that…

Q: What are DNA methyltransferases (DNMTS) ?

A: Enzymes are protein molecules that aid in increasing the rate of metabolism and chemical reactions…

Q: Why aren’t primary rRNA transcripts present in wild-type E. coli?

A: E.coli is a gram negative, faculatative anaerobic, rod-shaped, coliform bacterium of the genus…

Q: . Can a missense mutation of proline to histidine bemade with a G • C → A • T transition-causing…

A: A missense mutation is a point mutation that occurs in a codon that codes for a different amino acid…

Q: What is the purpose of the random hexamer primers?

A: A primer is a nucleotide sequence which acts as a start point for DNA synthesis Primers is…

Q: What mutagen results to the formation of thymine dimers?

A: Asked : Mutagen which results to the formation of thymine dimers

Q: Why eukaryotic genes are called split genes?   What is alternative RNA splicing?

A: Gene is the biological and functional unit of cells. They consists of DNA that is present on the…

Q: How many exons has the CFTR gene?

A: Introduction :- The CFTR gene encodes a membrane protein and chloride channel in vertebrates called…

Q: How do type IA, type IB, and type II topoisomerases alter DNA topology?Which processes require the…

A: Enzyme is a catalytic molecule that increases the rate of any chemical reaction without being used…

Q: What is a complex of proteins that folds up the telomeres into a structure that shields…

A: A complex of protein is generally found in many eukaryotic cell, whose primary function is the…

Q: What is the minimal number of insertions/deletions of nucleotides that would result in a frameshift…

A: A mutation happens when a DNA (deoxyribonucleic acid) gene is broken or modified causing the change…

Q: What are DNA methyltransferases (DNMTs) ?

A: Enzymes are referred to as the molecules of proteins that help in increasing the metabolism rate and…

Q: How does somatic recombination differ from alternative splicing of RNA?

A: Recombination of DNA (deoxyribonucleic acid) refers to the formation of new DNA as a result of the…

Q: What factor might potentially determine the length of the flanking direct repeats that are produced…

A: Flanking or terminal repeats are the sequences DNA that are repeated on the both ends of a sequence…

Q: What is the probability that the palindromic symmetry of the trp repressor target DNA sequence is…

A: Palindromic sequences are the sequences present in the DNA double helix that are read the same from…

Q: Are there any distinctive features associated with TEs Transposable Elements? What are these?

A: Transposable elements have shaped the genome during evolution, allowing for the development of new…

Q: Why are frameshift mutations likely to be more detrimental than point mutations, in which a single…

A: A mutation is a permanent change in the DNA of a cell such that the sequence deviates from what is…

Q: What is single-nucleotide polymorphisms (SNPs) ?

A:

Q: How were the experimentally derived triplet codon assignments verified in studies using…

A: MS2 refers to an icosahedral, single-stranded, positive-sense RNA (ribonucleic acid) virus that…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.