Why do deficiencies in glucose 6-phosphate dehydrogenase frequently present as anemia?
Q: Identify the means by which the pyruvate dehydrogenase complex is regulated.
A: Pyruvate dehydrogenase is a convergence point in the regulation of the metabolic finetuning between…
Q: Explain why people with a deficiency of the enzyme glucose 6-phosphate dehydrogenase (G6PDH) suffer…
A: Glucose 6-phosphate dehydrogenase(G6PDH) deficiency is an X-linked disease. In normal, G6PD is…
Q: Why Alpha-Ketoglutarate dehydrogenase (a-KGDH) called deficiency? What are the probable causes?…
A: Alpha-ketoglutarate dehydrogenase (alpha-KGDH) is a tightly controlled enzyme that regulates…
Q: What is the function of the kinase associated with the pyruvate dehydrogenase complex?
A: Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into…
Q: How are the irreversible reactions of glycolysis bypassed in gluconeogenesis?
A: Introduction: Gluconeogenesis is a metabolic pathway where glucose is synthesized from…
Q: Which isoenzyme of Lactate dehydrogenase is present in blood?.
A: Isoenzymes are physically different from of enzyme that catalyses same biochemical reactions.
Q: Acute intermittent porphyria is caused by deficiency of enzyme?
A: Porphyria is a group of disorder that occurs due to accumulation of a protein porphyrin, which…
Q: How might the level of HMG-CoA reductase activity be altered by the enzyme deficiency?
A: CHOLESTEROL is important in eukaryotic cell membranes. It is also a precursor of steroid hormones,…
Q: What happens to ketone body production during cases of prolonged hypoglacemia?
A: Hypoglacemia is a condition occurring in a body where in the blood glucose levels falls below a…
Q: What is the product of the reaction when alpha-amylase acts on amylose?
A: Amylase is an enzyme that catalyzes the hydrolysis of starch. It is present predominantly in the…
Q: In the reaction catalyzed by malate dehydrogenase, what molecules are classified as the reduced…
A: Malate dehydrogenase is an oxidoreductase class enzyme, which is involved in citric acid cycle and…
Q: What is the disease due to the lack of enzyme for the alpha-oxidation. Explain.
A:
Q: How would the body be affected by a drug that selectivelyinhibited lipoxygenase?
A: Lipoxygenases are the family of enzymes acting on polyunsaturated fatty acids possessing multiple…
Q: Lesch nyhan syndrome is due to deficiency of which enzyme ?
A: Lesch nyhan syndrome is a rare inherited disorder which occurs exclusively in males, due to…
Q: Explain the physiological role of transacetylase ?
A: Transacetylase is an enzyme that transfers an acetyl-CoA to galactosides and lactosides. It is coded…
Q: What is ornithine transcarbamylase (OTC)deficiency ?
A: Ornithine transcarbamylase (OTC)deficiency is a rare x linked recessive genetic disorder…
Q: What is the action of Amylase?
A: Action of Amylase is that it converts the starch present in the food into the sugar. Amylases are…
Q: How are enzymes in Citric Acid Cycle regulated? What are these enzymes and their inhibitors?
A: Cellular metabolism is the set of all reactions that are involved in producing energy in the body.…
Q: What enzymes outside of the citric acid cycle affect itsregulation?
A: Citric acid cycle is also known as the tricarboxylic acid [TCA] cycle and Krebs cycle. The pyruvic…
Q: 24.92 How is pyruvate metabolized in red blood cells, which contain no mitochondria?
A: The main source of carbohydrate is glucose in the body and its metabolism is called glycolysis. The…
Q: What effect does a higher ADP/ATP ratio have on isocitrate dehydrogenase activity?
A: Isocitrate dehydrogenase is an enzyme that catalyzes isocitrate's oxidative decarboxylation,…
Q: How does increasing the ADP/ATP ratio influence isocitrate dehydrogenase activity?
A: A Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate, resulting in…
Q: How intravenous infusion of glucose provide carbohydrate calories to patients?
A: Glucose is a type of sugar. It provides energy to our body. glucose is naturally present in the body…
Q: How many moles of Acetyl CoA are produced from the beta oxidation of Lauric Acid?
A: Biomolecules are organic molecules present in living organisms. The major biomolecules are proteins,…
Q: How would the rapid accumulation of succinyl-CoA affect the rate of glucose oxidation?
A: Cellular Respiration is the oxidative process through which energy is obtained from the food. The…
Q: What glycolytic enzyme appears to be impaired?
A: Glycolysis is the pathway in which glucose molecules are broken down to pyruvate. During this…
Q: How do the cytosolic and mitochondrial isozymes of glycerol 3-phosphate dehydrogenase differ from…
A: Glycerol-3-phosphate dehydrogenase, abbreviated as GPDH is an enzyme that is responsible for the…
Q: How many FADH2 _____& ATP _____are produced from the beta oxidation of Lauric Acid?
A: Beta oxidation is a catabolic process involved in the fatty acid breakdown for energy production.
Q: What is the substrate for the enzyme alpha-amylase?
A: Alpha-amylase (-amylase) is an enzyme with the EC number 3.2.1.1 that breaks down alpha bonds in…
Q: What is the clinical and diagnostic significance of alpha-amylase?
A: Alpha-amylase is an enzyme that works on the hydrolysis of starch and other polysaccharides.…
Q: Pernicious anemia. Purine biosynthesis is impaired by vitamin B12 B12 deficiency. Why? How might…
A: Pernicious anemia is a type of anemia. This is a condition in which the blood has a lower than…
Q: What type of reaction is catalyzed by isocitrate dehydrogenase and a-ketoglutarate dehydrogenase?
A: Oxidative decarboxylation is a process in which carbon dioxide is produced through the removal of a…
Q: In own words, give 5 or more reasons why most of the clinical features of the diseases…
A: Mitochondria are an essential component of eukaryotic cells, and their failure has been linked to a…
Q: What is the ATP yield from the oxidation of one molecule of nervonic acid?
A: During the prolonged fasting condition and when the level of glucose decreases inside the body, to…
Q: Why edema is present in protein deficiency?
A: Protiens are the basic building blocks of the body. They are used to make build cells, structural…
Q: Infants do not have the ability to metabolize ethanol and are assumed to lack the enzyme alcohol…
A: Ethanol is used for in neonatal and infant liquid medications. However, the pharmacokinetics,…
Q: What is the condition associated with a deficiency on enzyme phenylalanine hydroxylase? albinism…
A: Enzymes are the catalysts that carry out biochemical reactions. These are proteins in nature.…
Q: How does an increase in the ADP/ATP ratioaffect the activity of isocitrate dehydrogenase?
A: Isocitrate dehydrogenase and is an enzyme that catalyses the oxidative decarboxylation of…
Q: How many moles of ATP are produced by the complete oxidation of 1 mol of myristic acid?
A: The Oxidation of Fatty acid takes place in the mitochondrial of the cell and it consists of three…
Q: What are some known disorders or diseases caused by abnormal structure and function of alcohol…
A: Alcohol dehydrogenase (ADH) is an enzyme responsible for the interconversion of ethanol and…
Q: Why most of the clinical features of the diseases Krebs Cycle inborn errors ( a- ketoglutarate…
A: Krebs cycle : This pathway plays an important role in the living cell metabolism also known as…
Q: What happened if we add normal saline instead of PBS during beta-amylase extraction?
A: Most enzymes are proteins. Their catalytic activity depends on the integrity of their native…
Q: what is the disease disorder due to deficiency of propionly CoA carboxylase enzyme ?
A: The carboxylation of propionyl CoA in the mitochondrial matrix is catalyzed by the enzyme…
Q: When the enzyme is incubated with oxaloacetate, will oxaloacetate be observed?
A: Many amino acid biosynthetic pathways involve transamination reactions. The α-amino group from one…
Q: How does compromised pyruvate kinase activity lead to anemia?
A: Pyruvate kinase is a catalytic enzyme that catalyzes the final step of glycolysis, which is crucial…
Why do deficiencies in glucose 6-phosphate dehydrogenase frequently present as anemia?
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- Infants do not have the ability to metabolize ethanol and are assumed to lack the enzyme alcohol dehydrogenase? What kind of regulation is this?How does an increase in the ADP/ATP ratioaffect the activity of isocitrate dehydrogenase?What are the effects of Glucose-6 Phosphate Dehydrogenase Deficiency? Explain its mechanism of action.
- When the enzyme is incubated with oxaloacetate, will oxaloacetate be observed?Why most of the clinical features of the diseases Krebs Cycle inborn errors ( a- ketoglutarate dehydrogenase deficiency, succinate dehydrogenase deficiency, and fumarase deficiency) involve muscle and nerve tissue?What is the clinical and diagnostic significance of alpha-amylase?