why is chymotrypsin inactive at high pH?

Q: Which functional groups of the amino acid residues are capable of ionization?

A: The functional groups that act as a proton acceptor or proton donor influencers the capacity for a…

Q: What do you mean by dehydogenase. Elaborate on their function in general ?

A: Enzymes are biological molecules that significantly speed up the rate of virtually all of the…

Q: Why Pancillin G is more potent than Nafcillin sodum and Methicillin sodium?

A: A bacterium is a cell, complete with a cell membrane primarily made of lipids. It also contains…

Q: How many high-phosphoryltransferpotential molecules are required to synthesize…

A: The cell membranes are composed of phospholipids, a complex class of lipids in which phosphate is…

Q: How are the structures of the ACE inhibitors captopril and enalapril similar? How are they…

A: ACE inhibitors stand for angiotensin-converting enzyme inhibitors that are principally accountable…

Q: What is the major function of Chemokines?

A: Chemokines activated Lymphocytes to site with tissue damage. They also transmit signals through…

Q: What is the weight of epinephrine (in grams) required to make the prescription? What is the volume…

A: Epinephrine hydrochloride is also known as adrenaline, it is a neurotransmitter and hormone that is…

Q: Why does trypsin inhibitor exist?

A: Trypsin is an enzyme secreted in the small intestine to continue the process of protein digestion…

Q: What is Cohesin Complex?

A: DNA ( deoxyribonucleic acid) is the genetic material that the organism inherits from the parental…

Q: What are clinical benefits of biphosphonates use?

A: The main framework of the body is the skeleton and it helps in supporting and protecting the organs,…

Q: What chemical species does chymotrypsin stabilize the most during the course of the reaction ?

A: Chymotrypsin is a serine protease. Serine protease is a class of proteolytic enzyme which catalytic…

Q: WHat is  the pI or isoelectric point of bradykinin? Explain

A: Bradykinin is a protein made of amino acids. Amino acids are the building blocks of proteins. There…

Q: Determine the type of inhibition by AMP? Explain

A: Inhibitors are substances which inhibit the enzyme activity by binding to the active site or…

Q: What is another function of oxytocin?

A: The hormone is known to be the regulatory substance of the body. It is synthesized in an organism…

Q: What two types of defensins contribute to the biochemical barrier?

A: Biochemical barriers are the chemical molecules synthesized within the body that act as a defence…

Q: What is the source of Chemokines?

A: The heparin binding proteins that direct the movement of circulating leukocytes to the site of…

Q: Why does Glutathione have a low bioavailability when applied topically

A: Glutathione is a skin whitening chemical substance

Q: What two biochemical roles does CCK play? GLP-1?

A: Cholecystokinin (CCK) is a peptide hormone of the gastrointestinal system and is responsible for…

Q: In what disease is a decrease in sphingomyelin observed?

A: Sphingomyelin, type of sphingolipid found in the cell membrane of animal cells, especially in the…

Q: What is the ionization state of phosphoric acid in the cytoplasm? Why is phosphoric acid such a…

A: Phosphoric acid is a phosphorus-containing inorganic acid that is colorless and odorless. Phosphoric…

Q: Why fibrinopepetide A and fibrinopepetide B are negatively charged ?

A: Proteins are made up of amino acids joined together through peptide bonds. 20 standard amino acids…

Q: How was thermal stability measured in this paper and describe how GRL-1720 and 5h affect the thermal…

A: Introduction- The Given article is about the novel coronavirus disease 2019 (COVID-19) which was…

Q: In humans the purine ring cannot be degraded. How is itexcreted? What reactions are involved?

A: Purine is a heterocyclic aromatic organic compound that consists of two rings. It is water-soluble…

Q: What oxidizes fadh2?

A: The process of Oxidative phosphorylation harness energy through the electron transport chain and ATP…

Q: How do the changes in structure, polarity and functional groups affect the movement of diazepam…

A:

Q: Why Valinomycin is highly selective for K+ relative to Na+?

A: Valinomycin is a naturally occurring dodecadepsipeptide used in the transport of potassium and as an…

Q: How are H^3 peptides used to study intracellular pathways?

A: A chain of reactions that transmits signals from the cell surface to intracellular targets. This…

Q: Why do individuals who are undergoing chemotherapy with FdUMP or methotrexate often temporarily go…

A: Methotrexate is a major group of chemotherapy drugs; they are also known as anti metabolites. These…

Q: What is Pindolol durg stability in various ph, temperature, and other condition?

A: Pindolol is in a group of drugs called beta-blockers which affect the heart and circulation-blood…

Q: What differences between proteins are responsible for their differential solubility in ammonium…

A: Ammonium sulphate is an inorganic salt with a number of commercial uses. The most common use is  as…

Q: What effects do increased pH and increased temperature have on the activity of trypsin?

A: An enzyme has an optimum pH and temperature at which its activity is maximum. The increase in enzyme…

Q: Nitrates, such as nitroglycerin, have what mechanism of action? Based on this mechanism of action,…

A: Nitroglycerin is a vasodilator which give relief from the symptoms of angina, high BP.

Q: Is there a difference between the effects of acid concentrations on protein denaturation? Why?

A: Acids  can significantly change the environmental pH of proteins, which disrupts the salt bridges…

Q: What are MTPs ? Under what conditions MTPs are legally permitted?

A: Reproduction is not always successful and some genetic and/or epigenetic factors produce one or more…

Q: What structural characteristics of mucopolysaccharides facilitate the removal of pathogens?

A: Mucopolysaccharides, also known as GlycosAminoGlycans (GAGs) are negatively charged polysaccharide…

Q: How is the activity of amylase affected by a low pH? By a high pH? Explain.

A: Every enzyme has an active site at the substrate-binding site, and the shape of the active site…

Q: What is the biochemical rationale for ATP serving as a positive regulator of ATCase?

A: Introduction: The first step in the pyrimidine biosynthetic pathway is catalysed by aspartate…

Q: What Are the General Features of AllostericRegulation?

A: In biochemistry, allosteric regulation (or allosteric control) is the binding of an effector…

Q: Dehydroascorbate is unstable at pH values greater than 6 and decomposes to form tartrate and…

A: Ascorbate is the active form of vitamin C. It is the in reduced form. This gets converted to…

Q: Chymotrypsin preferentially binds the transition state. What is meant by that?

A: Transition state is free energy maximum state. It is an intermediate stage of enzyme-catalyzed…

Q: What beneficial properties of rasagiline make it useful for the treatment of Alzheimer’s disease?

A: Alzheimer's disease is a brain disorder. In this neurological disorder, the brain loses its ability…

Q: What biochemical reaction is catalyzed by γ-secretase? Why was it proposed that a chemical inhibitor…

A: Enzymes are proteins with catalytic power.

Q: Inhibition of oxamic acid causes what type of inhibition?

A: Oxamic acid is an organic acid with the molecular formula H2NC(O)CO2H. Oxamic acid is synthesized…

Q: TWO of the following statements about Extended Spectrum ß-lactamases are CORRECT?

A: Numerous bacteria produce various enzymes and metabolites that are capable of making the bacteria…