* Write out all the steps in the mechanism of this electrophilic aromatic substitution reaction. Include all resonance contributors. CH3CI Benzene →acetophenone AICI3
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- Please I need help with this question Based on the experiment- Synthesis of Iodosalicylamide – An Electrophilic AromaticSubstitution (a derivative of benzene, salicylamide was used and substituted an iodine atom onto the ring; the ring is the nucleophile while the atom/molecule that is being substituted onto the ring has anelectrophilic character) Please I need help with this QUESTION: Draw the structure of the final product(s) based on the ATTACHED IR analysis. Also label the signals (both the frequency and molecular motion) that help determine the final product(s). Thanks in advanceIllustrate the resonance effect of the methoxy group -OCH3, on the structure of the benzene ring. Draw all the oissuvke resonance forms of methoxybenzene, including the hybrid Based on the structures, explain how the presence of the -OCH3 group affects: (i) the reactivity of the benzene ring towards electrophilic attack (ii) the orientation or point of attack of an incoming electrophilic reagent on the benzene ring.Draw the molecule: Under second-order conditions (strong base/nucleophile), SN2 and E2 reactions may occur simultaneously and compete with each other.Show what products might be expected from the reaction of 2-bromo-3-methylbutane (a moderately hindered 2∘∘ alkyl halide) with sodium ethoxide. Do not worry about sterechemistry inther SN2 product for this problem. Don't forget about stereochemistry.
- Write out all the steps in the mechanism of this electrophilic aromatic substitution reaction. Include all resonance contributors. Benzene -HNO3-----> nitrobenzene H2SO4what are the 8 steps needed to make this benzene ring into the substituted benzene derivative shown belowUnder second-order conditions (strong base/nucleophile), SN2 and E2 reactions may occur simultaneously and compete witheach other. Show what products might be expected from the reaction of 2-bromo-3-methylbutane (a moderately hindered 2°alkyl halide) with sodium ethoxide.
- Aromatic heterocycles can undergo electrophilic aromatic substitution like benzene. Groups attached to the heterocycle can therefore have similar directing effects as they can on benzene. Keeping this in mind, consider the following reaction, where E+ is a general electrophile: a) Draw all relevant resonance structures for the intermediate of each product b) Based on your answers to part a), which product do you expect to be the major product and why? (2 points)c) If you performed this reaction in the laboratory, which instrumental technique (ex: 1H NMR, IR, Mass Spectrometry) would be best to determine which product you obtained of the three and why?These two compounds shown go through SN1 substitution at a speed similar to some tertiary halides, even though the following compounds represent primary and secondary halides. Explain the enhanced reactivity via resonance structures and pushing arrows.In Image 4 predict the effect the substituent attached to the benzene ring would have on electrophilic aromatic substitution reactions? a.ortho/para director, deactivator b.ortho/para director, activator c.meta director, activator d.meta director, deactivator
- Draw the products and necessary reagents of the three step retrosynthetic reaction sequence shown below. Use wedge and dash bonds to indicate stereochemistry where appropriate. Ignore inorganic byproducts. Please choose from the following options for each of the reagents. (top reagents options) A. HNO3, cat. H2SO4 B. SO3, cat. H2SO4 C. CH3C(=O)Cl, AlCl3 D. Cl2, FeCl3 E. H2O, HCl (reagents option to the right) (top reagents options) A. HNO3, cat. H2SO4 B. SO3, cat. H2SO4 C. CH3C(=O)Cl, AlCl3 D. Cl2, FeCl3 E. H2O, HClUnder second-order conditions (strong base/nucleophile), SN2 and E2 reactions may occur simultaneously and compete with each other. Show what products might be expected from the reaction of 2-bromo-3-methyl butane (a moderately hindered 2∘ alkyl halide) with sodium ethoxide. Do not worry about stereochemistry in the SN2 product for this problem. Don't forget about stereochemistry.Help ASAP Illustrate the resonance effect of the methoxy group -OCH3, on the structure of the benzene ring. Do this by writing all the possible resonance forms for methoxybenzene, including the hybrid. Based on your structures, explain how the presence of the -OCH3 group affects: (i) the reactivity of the benzene ring towards electrophilic attack; (ii) the orientation or point of attack of an incoming electrophilic reagent on the benzene ring.
