You are requested to recommend a dosage regimen for a patient (55 years old, 80 kg) to achieve plasma levels of 25 mg/L of an antiepileptic agent with an elimination half-life of 11 hrs and an apparent Vd of 0.02 L/kg. The tablets are 75% bioavailable and are available as 10 mg and 40 mg tablets. The ideal dosage regimen for this patient is: 10 mg twice daily 10 mg four times a day 40 mg daily 40 mg twice daily

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 7.7P
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You are requested to recommend a dosage regimen for a patient (5S years old, 80 kg) to achieve plasma levels of
25 mg/L of an antiepileptic agent with an elimination half-life of 11 hrs and an apparent Vd of 0.02 L/kg. The
tablets are 75% bioavailable and are available as 10 mg and 40 mg tablets. The ideal dosage regimen for this
patient is:
10 mg twice daily
10 mg four times a day
40 mg daily
40 mg twice daily
Transcribed Image Text:You are requested to recommend a dosage regimen for a patient (5S years old, 80 kg) to achieve plasma levels of 25 mg/L of an antiepileptic agent with an elimination half-life of 11 hrs and an apparent Vd of 0.02 L/kg. The tablets are 75% bioavailable and are available as 10 mg and 40 mg tablets. The ideal dosage regimen for this patient is: 10 mg twice daily 10 mg four times a day 40 mg daily 40 mg twice daily
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