You are working in a research lab with a drug that temporarily blocks the reuptake pump (Calcium-SR ATPase) for calcium in a muscle cell. You have two intact muscle cells. One you administer the calcium blocker and one you do not (normal cell). The same stimulus is applied to both muscles. How will the administration of the drug affect the cytosolic calcium concentration, and consequently, the muscle contraction of the blocked cell? (hint: draw this out before just answering, where is this ATPase located?) a. The blocked cell will have a lower cytosolic calcium concentration; therefore the muscle will return to the resting state compared to the normal cell. b. The blocked cell will have a lower cytosolic calcium concentration; therefore the muscle will contract with the same force as the normal muscle cell. c. The blocked cell will have a lower cytosolic calcium concentration; therefore the muscle will contract with greater force compared to the normal cell. d. The blocked cell will have a greater cytosolic calcium concentration; therefore the muscle will contract with the same force as the normal muscle cell. e. The blocked cell will have a greater cytosolic calcium concentration; therefore the muscle will contract with greater force than the normal muscle.
You are working in a research lab with a drug that temporarily blocks the reuptake pump (Calcium-SR ATPase) for calcium in a muscle cell. You have two intact muscle cells. One you administer the calcium blocker and one you do not (normal cell). The same stimulus is applied to both muscles. How will the administration of the drug affect the cytosolic calcium concentration, and consequently, the muscle contraction of the blocked cell? (hint: draw this out before just answering, where is this ATPase located?) a. The blocked cell will have a lower cytosolic calcium concentration; therefore the muscle will return to the resting state compared to the normal cell. b. The blocked cell will have a lower cytosolic calcium concentration; therefore the muscle will contract with the same force as the normal muscle cell. c. The blocked cell will have a lower cytosolic calcium concentration; therefore the muscle will contract with greater force compared to the normal cell. d. The blocked cell will have a greater cytosolic calcium concentration; therefore the muscle will contract with the same force as the normal muscle cell. e. The blocked cell will have a greater cytosolic calcium concentration; therefore the muscle will contract with greater force than the normal muscle.
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter7: The Peripheral Nervous System: Efferent Division
Section: Chapter Questions
Problem 1SQE
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Transcribed Image Text:You are working in a research lab with a drug that temporarily blocks the reuptake pump (Calcium-SR ATPase) for calcium in a muscle cell. You have two intact muscle cells. One
you administer the calcium blocker and one you do not (normal cell). The same stimulus is applied to both muscles. How will the administration of the drug affect the cytosolic
calcium concentration, and consequently, the muscle contraction of the blocked cell?
(hint: draw this out before just answering, where is this ATPase located?)
a. The blocked cell will have a lower cytosolic calcium concentration; therefore the muscle will return to the resting state compared to the normal cell.
b. The blocked cell will have a lower cytosolic calcium concentration; therefore the muscle will contract with the same force as the normal muscle cell.
c. The blocked cell will have a lower cytosolic calcium concentration; therefore the muscle will contract with greater force compared to the normal cell.
d. The blocked cell will have a greater cytosolic calcium concentration; therefore the muscle will contract with the same force as the normal muscle cell.
e. The blocked cell will have a greater cytosolic calcium concentration; therefore the muscle will contract with greater force than the normal muscle.
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