You discover two segregating genes (A and B) that affect resistance in a population of snails. You are interested in determining if the two loci are in LD. You analyzed 100 snails for allelic and haplotype states, and observed the frequencies reported in the table below. a. Calculate D for genes A and B. (D = gAB9ab - GAB9AB) b. Is this population in linkage equilibrium or linkage disequilibrium with respect to genes A and B? Frequency Allele A Allele a 0.6 0.4 Allele B 0.8 Allele b 0.2 0.48 Haplotype AB Haplotype Ab 0.12 0.32 Haplotype aB Haplotype ab 0.08

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter19: Population Genetics And Human Evolution
Section: Chapter Questions
Problem 8QP: How Can We Measure Allele Frequencies in Populations? In a population where the females have the...
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You discover two segregating genes (A and B) that affect resistance in a population of snails. You are interested in determining if the two loci are in LD. You analyzed 100 snails for allelic and haplotype
states, and observed the frequencies reported in the table below.
a. Calculate D for genes A and B. (D = gAB9ab - gAb9aB)
b. Is this population in linkage equilibrium or linkage disequilibrium with respect to genes A and B?
Frequency
Allele A
0.6
Allele a
0.4
Allele B
0.8
Allele b
0.2
Haplotype AB
Haplotype Ab
Haplotype aB
Haplotype ab
0.48
0.12
0.32
0.08
Transcribed Image Text:You discover two segregating genes (A and B) that affect resistance in a population of snails. You are interested in determining if the two loci are in LD. You analyzed 100 snails for allelic and haplotype states, and observed the frequencies reported in the table below. a. Calculate D for genes A and B. (D = gAB9ab - gAb9aB) b. Is this population in linkage equilibrium or linkage disequilibrium with respect to genes A and B? Frequency Allele A 0.6 Allele a 0.4 Allele B 0.8 Allele b 0.2 Haplotype AB Haplotype Ab Haplotype aB Haplotype ab 0.48 0.12 0.32 0.08
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