You want to mutate a Trp residue which is located in the interior of a protein structure. Which of the following mutations would have the most destabilizing effect? a) Phe b) Pro c) Gly d) Ala e) Arg

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter10: From Proteins To Phenotypes
Section: Chapter Questions
Problem 20QP: If an extra nucleotide is inserted in the first exon of the beta globin gene, what effect will it...
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You want to mutate a Trp residue which is located in the interior of a protein structure. Which of the following mutations would have the most destabilizing effect?

a) Phe
b) Pro
c) Gly
d) Ala
e) Arg
 
 
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