You want to prepare a Glycine buffer (pKa’s 2.3 and 9.6) to simulate the pH in the intestine. You decide to make 150 mL of 300 mM glycine at pH 8.6. However, you only have glycinyl chloride (MW 111.5), 10 M HCl, 10 M NaOH, and water. Describe how to make this buffer with these materials

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter15: Acid-base Equilibria
Section: Chapter Questions
Problem 20Q: Consider the following two acids: pKa1 = 2.98; pKa2 = 13.40 HO2CCH2CH2CH2CH2CO2H Adipic acid pKa1 =...
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You want to prepare a Glycine buffer (pKa’s 2.3 and 9.6) to simulate the pH in the intestine. You decide to make 150 mL of 300 mM glycine at pH 8.6. However, you only have glycinyl chloride (MW 111.5), 10 M HCl, 10 M NaOH, and water. Describe how to make this buffer with these materials.

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