CF3 CF3 O,N. N. H Flutamide Trifluoromethyl- benzene (Eulexin)

Chemistry: Matter and Change
1st Edition
ISBN:9780078746376
Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Publisher:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Chapter23: The Chemistry Of Life
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Cancer of the prostate is the second leading cause of cancer deaths among American males, exceeded only by lung cancer. One treatment of prostate cancer is based on the fact that testosterone and androsterone (both androgens) enhance the proliferation of prostate tumors. The drug flutamide (an antiandrogen) reduces the level of androgens in target tissues and is currently used to prevent and treat prostate cancer.Propose a synthesis of flutamide from trifluoromethylbenzene

CF3
CF3
O,N.
N.
H
Flutamide
Trifluoromethyl-
benzene
(Eulexin)
Transcribed Image Text:CF3 CF3 O,N. N. H Flutamide Trifluoromethyl- benzene (Eulexin)
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