Erythropoietin

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  • Erythropoietin : Is It Worth It?

    1542 Words  | 7 Pages

    Erythropoietin: Is it worth it? Carriella Starnes Emory & Henry College Over a century ago Eugene Goldwasser and Takaji Miyake worked together in Chicago to synthesize the human hormone erythropoietin, better known as EPO. It took over 10 years for EPO to be approved by the Food and Drug Administration to be used solely for patients with anemia. EPO is naturally produced by the kidneys and is sensitive to the oxygen levels in the blood. When oxygen levels are too low, EPO is released

  • Hepcidi Lab Report

    1053 Words  | 5 Pages

    and is affiliated with erythropoietin receptor (Epor) in erythroid cells (1, 2). A mutation in Tfr2 leads to an iron overload disease known as haemochromatosis (Hfe) type 3, without any apparent erythroid irregularities (1). Tfr2 is a constituent of an atypical iron-sensing pathway that adapts erythrocyte production, according to iron accessibility, achievable by modulating the erythroblast erythropoietin sensitivity (1). The red blood cell (RBC) specific hormone erythropoietin (Epo) accounts for the

  • Secondary Polycythemia

    707 Words  | 3 Pages

    Erythropoietin secretion is regulated in the kidneys; it is an acidic glycoprotein, produced primarily in the renal cortex (Jelkmann, 2011). Two events happen to stimulate the release of erythropoietin. First, a transcription factor called GATA-2 (which prohibits Erythropoietin secretion in the presence of normal oxygen levels) decreases in instances of hypoxia allowing for erythropoietin secretion. Second, certain transcription factors called

  • Blood Doping : Can We Beat It?

    1347 Words  | 6 Pages

    Artificial erythropoietin can also be used. By increasing the number of erythropoietin in your blood you increase the amount of oxygen that can be brought to your muscles and organs, resulting in fewer discomfort in muscles during workout and more endurance, stamina, and enhanced performance. Blood

  • How Drugs Affects The Body And The Side Effects Of The Drugs

    1429 Words  | 6 Pages

    focusing on for this issues analysis will be- Erythropoietin- Blood doping and Anabolic steroid’s Paragraph 1: Some of the variants of drugs that are most commonly utilized in sports is Erythropoietin, blood doping, anabolic steroids and human growth hormones. Erythropoietin is a drug that can be used to increase an athlete’s performance. Some of the side effects of using Erythropoietin are major and can be fatal, the side effects of using Erythropoietin are increased viscosity of the blood meaning

  • Problems With Chronic Renal Failure

    1306 Words  | 6 Pages

    Mark is a four year old male who has been diagnosed with chronic renal failure. Mark has two older brothers, John and Max. His mom, Carol, is a teacher at the local elementary school. His dad, Mike, is a community police officer. Mark goes to preschool from 0800-1200 four days a week. They live in a rural community in small four bedroom house with their dog, Bruno. Everyone in the community seems close and supportive. Both Mark’s older brothers caught strep throat at school and then Mark caught it

  • Diagnosis Of The Patients With Chronic Kidney Disease

    1850 Words  | 8 Pages

    THE HAEMATOLOGICAL PATTERN OF THE PATIENTS WITH CHRONIC KIDNEY DISEASE IN A TERTIARY CARE SETUP IN SOUTH INDIA Dr.S.Palaniandavan** Dr.M.V.Bhargavi*** *Professor and head of the department **Assistant professor General medicine department Sree Balaji medical college and hospital, Chromepet, Chennai. ABSTRACT Background: With the incidence and the prevalence of chronic kidney disease (CKD) increasing worldwide and its economic repercussions, a detailed haematological workup of such

  • Blood Doping, Human Growth Hormones, Steroid, Beta 2 Agonists

    1526 Words  | 7 Pages

    Erythropoietin (EPO), blood doping, human growth hormones, steroid, beta-2 agonists. These are a few substances that come into mind when discussing the topic 'performance enhancing drug ' also known as doping. Doping is defined as the use of drugs to enhance performance and gain advantage over the other competitors, and it has been an ongoing problem in the sport community since the early centuries, with an increasing trend showing today. Envision yourself competing against an opponent who has been

  • The Complications Of Kidney Failure

    1611 Words  | 7 Pages

    of waste and other fluids. • Dialysis is often a last resort for people that are undergoing kidney failure. Possible Complications of Kidney Failure • Anemia and Erythropoietin (EPO) – Erythropoietin is produced by the kidneys and is the hormone that regulates the production of red blood cells. The kidneys don’t make enough erythropoietin, so there are fewer blood cells, which can lead to anemia. • Renal Osteodystrophy – Since the kidneys can’t regulate the proper chemical levels in the blood during

  • Anemi Common Systemic Consequence Of Chronic Kidney Disease ( Ckd )

    1153 Words  | 5 Pages

    2014). As CKD continues to become worse, the individual is at higher risk for developing anemia. More than 40% of patients in stage V CKD develop anemia (Shemin, 2014). CKD leads to anemia due to a decrease or deficit in the production of erythropoietin (EPO) (Shemin, 2014). Bone marrow receptors are stimulated by EPO, a 165 amino acid protein, the stimulation leads to the production and promotion of red blood cell precursors into mature erythrocytes (Shemin, 2014). Since EPO is synthesized

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