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    The treatment of sickle cell anemia with high concentrations of fetal hemoglobin with correct bacterial strain Brandon Frey, Sebastian Dziadowicz, Jeremy Eckels, David Lyons November 17, 2016 Table of Contents Cover Page…………………………………………………………………. 1 Table of Contents…………………………………………………………… 2 Executive summary…………………………………………………………. 3 Introduction…………………………………………………………………. 3-4 Methods…………………………………………………………………....... 4 Results and Discussion……………………………………………………… 4-6 Summary and Recommendations……………………………………………

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    Cloning, landmine sensing plants, and fish that glow in the dark, are all realities when it comes to the possibilities of genetic engineering. Genetic engineering is the artificial modification of an organisms genetic material with the help of biotechnology. This is capable of producing traits in an organism that would never have occurred by naturally. Genetic engineering is possible because genes are a universal language in life. Genes from one organism can be put in another organism, the possibilities

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    Gene imprinting is an epigenetic phenomenon when two alleles of a certain gene are expressed at different level depending on their parent-of-origin. Gene imprinting has been documented in mammals and flowering plants. In the 1980s, biologists’ attention to imprinting has greatly increased due to the recognition of its importance during mammalian development [1]. Imprinted genes regulate cell growth, cell signaling, cell cycle regulation, and influence nutrient acquisition and fetus growth. In mammals

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    share our thoughts and ideas with others, which in turn can allow us to grow individually and as a society. According to Michael Aliprandini and Geraldine Wager, authors of “Censorship”, censorship is “the suppression of information, opinion, or expression by a government or other authority in order to control their circulation” (Aloprandini). Many areas of life can been censored, but perhaps the most recognizable from of censorship comes in the form of books. When it comes to the United States, books

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    Alcohol Resistance Essay

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    The purpose of this experiment is to confirm which variant (SNP) is associated with Alcohol resistance. To test which of the variants causes the phenotype, I will use CRISPR/Cas9 genome editing technology to edit single nucleotide and insert nucleotides. (i) Animals: 6 adult mice will be used. • # 1 mouse: normal Tap water • # 2 mouse: ethanol with no mutation • # 3 mouse: ethanol with SNP in Gene A amino acid region • # 4 mouse: ethanol with SNP in Gene B 5’UTR • # 5 mouse: ethanol with insertion

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    The authors’ goal in conducting this experiment was to establish a link between, among other things, protein degradation through the ubiquitin-protease system (UPS) and the consolidation and reconsolidation of long-term fear memories. This research was necessary because, while research had been done linking protein degradation to synaptic plasticity, no study had been performed to analyze the role of UPS in the amygdala, where long-term fear memories are believed to be stored. Additionally, prior

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    Metcalf et al. 1995, Kiyoi and Naoe 2002, D Kottaridis, Gale et al. 2003, Levis and Small 2003, Stirewalt and Radich 2003, Naoe and Kiyoi 2004, Kiyoi, Yanada et al. 2005). In normal bone marrow, expression appears to be restricted to early progenitors, includingCD34_ cells with high levels of expression of CD117 (c-KIT)(Rasko, Metcalf et al. 1995, Drexler 1996, Kiyoi, Yanada et al. 2005). FMS-like tyrosine kinase-3 receptor is also expressed at high levels in a spectrum of hematologic malignancies

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    Mast Cell Case Study

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    challenge, although the number of dendritic cells increased post-antigen challenge. Within the trachea, dendritic cells were found to extend dendritic projections under the airway epithelium but not into the airway lumen. Mast cells were found to probe the vasculature with the probing frequency increasing post-allergen challenge53. Whether intraluminal dendrite scanning employed by mast cells has other functional roles needs to be evaluated further. Within the skin, mast cells are distributed throughout

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    Therefore, we are aiming to elucidate the potential of 5-ALA/PDT to target the genetic materials of MCF-7 and HepG2 cancer cell lines effectively after inducing cytotoxicity and genotoxicity by two cytogenetic parameters; micronucleus test and alkaline comet assay. In this experimental study, we will elucidate the potential of 5-ALA/PDT to target DNA and induce DNA damage to the genetic materials of MCF-7 and HepG2 cancer cells and record cytotoxicity and genotoxicity by micronucleus test and alkaline

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    ERG Essay

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    relapse or progression during the 10 years following surgery; it is intended to estimate the risk of tumor recurrence and to guide the adjustment of therapy accordingly [29]. Decipher Decipher is a transformative genomic test, which measures the expression levels of 22 RNA biomarkers involved in multiple biological pathways across the genome that are associated with aggressive PCa. The study, titled ‘‘Validation of a Genomic Classifier that Predicts Metastasis Following Radical Prostatectomy in an

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