Graft-versus-host disease

chronic inflammatory cell infiltrate. The immunopathologic feature of lichen planus demonstrates the deposition of a tangled band of fibrinogen at the basement membrane zone. Topical or systemic corticosteroids recommended for symptomatic patients. Disease course is variable but my be waxing or

All blood cells and components have vital roles making it necessary that they are replenished continuously; this is achieved by haematopoiesis, where there is a differentiation of a population of pluripotent cells, known as haematopoietic stem cells. HSCs are unspecialised cells that can be differentiated into multiple lineages (figure 1) of mature blood cells (Park et al., 2015). Not only do these cells possess the potential for multipotency they also have the ability of self-renewal, making them

profile and homing characteristics. Depending on where they are used, these characteristics can have a positive and negative influence on the disease. This review will focus on the immunomodulatory characteristics of MSCs, several isolation points of MSCs, and differentiation which make them useful tool in treatment of post myocardial infarction, diabetic foot disease (wounds), immune

battling with HIV for 11 years with antiretroviral drugs since 1995 when he was diagnosed. Then in 2006, he was being diagnosed with acute myeloid leukemia, another disease that would put his life in danger. Acute myeloid leukemia is a type of cancer that attacks the bone marrow and spread to blood.[9] To treat his new deadly disease, Brown has tried radiation and chemotherapy which both did not seem to be successful in helping him. In 2007 and 2008 he made the decision of going for a bone marrow

In oncological patients, diarrhea can occur in several different situations. Possible etiologies could be chemotherapeutic agents, radiation, decreased physical performance, graft vs. host disease and infections. “Of clinical importance is chemotherapy-induced diarrhea, which has been reported as a grade 3–4 serious adverse event with a frequency of 5–47% in randomized clinical trials” (Andreyev, 2014). Diarrhea is divided into different grading and these are Grade 1: increase to two to three bowel

Part I: Chronic granulomatous disease (CGD) is a hereditary immunodeficiency disease characterized by failure of phagocytic cells (neutrophils and monocytes) to effectively destroy invading bacteria and fungi. Due to a defect of nicotinamide adenine dinucleotide phosphate reactive oxygen species production and lack of bacterial killing, affected individuals are susceptible to serious, potentially life-threatening, bacterial and fungal infections but have normal immunity to viruses. They also experience

cells with special function. - They regularly divide to repair and replace worn-out or damaged tissues. The unique regenerative abilities of stem cells provide potential for treating diseases and many injuries, blood disorder, certain cancers such as Leukemia, and diseases such as diabetes and also heart diseases. Stem cells and their types Helpful stem cells Embryonic Stem cells Embryonic stem cells are the helpful type of stem cells in our body that can be used in many ways. One of

benefits of receiving a HSCT, there are serious complications to consider. Complications include thrombolytic events, infections, hepatic sinusoidal occlusive syndrome (formerly known as veno-occlusive disease and will be abbreviated in this paper as VOD/SOS), renal failure, graft-verse-host-disease, possible relapse and

divides, it has the capability of becoming another stem cell or become a more specialized type of cell that performs a specific function in the body. Stem cells in the treatment of cancer can be used to replace those cells that have been destroyed by disease, chemotherapy, or radiation. Types of Stem Cell Transplants: Typical treatments

potential to study and treat disease (Spitalieri et al., 2016). Embryonic stem cells (ESC) are pluripotent cells that emerge from the inner cell mass of the blastocyst and can give rise to various cell types (Liang and Zhang, 2013). Induced pluripotent stem cells (iPSC) have similar characteristics but are derived from adult differentiated somatic tissue (Liang and Zhang, 2013). This review will briefly compare ESC and iPSC in the context of cell therapy and disease modeling. The human ESCs have