Hyperforin

St. John's Wort As A Treatment For Depression: Herbal Healer or Ineffective Alternative? This country has its share of major health issues, and Depression has remained a prominent one. With a prevalence rate of one in twenty suffering from this psychological disease in the US, (1) it is no wonder that many varying treatment options now exist for sufferers. The most common approach to treating Depression is with some form of psychotherapy coupled with prescription drugs. However, this traditional

Western Scientific Medicine or WSM involves many healthcare professionals which include doctors pharmacists and therapists in which they try to treat diseases or disorders with drugs surgery or other forms of procedures such as radiotherapy. Traditional Medicine relates to many different cultures and the way that many cultures prevented mental and physical illness as well as diagnosing the disorder and improving the treatment. It is a total sum of different cultures combining the knowledge and skills

all the processes mentioned above, we have focused our study on hyperforin a Ca2+-modulator. Hyperforin is the natural and biologically active compound extracted from Hypericum perforatum (St John’s Wort) (26). Both St John’s Wort and hyperforin attenuated symptoms of mild to moderate depression in a few clinical trials and displayed antidepressant-like activity in preclinical studies (27, 28). From a molecular perspective, hyperforin has a multi-directional mechanism of action. It acts on ligand-gated

mentioned processes, we focused our interests on hyperforin which is Ca2+-modulator. Hyperforin is the natural and biologically active compound extracted from Hypericum Perforatum (St John Wort) (26). The St John Wort extract and hyperforin attenuated symptoms of mild to moderate depression in a few clinical trials. Both extract and hyperforin displayed antidepressant-like activity in preclinical studies (27, 28). From molecular perspective, hyperforin has multidirectional mechanisms of action. It

to all processes mentioned above, we have focused our study on hyperforin a Ca2+-modulator. Hyperforin is the natural and biologically active compound extracted from Hypericum perforatum (St John’s Wort) (26). Both St John’s Wort and hyperforin attenuated symptoms of mild to moderate depression in a few clinical trials and displayed antidepressant-like activity in preclinical studies (27, 28). From a molecular perspective, hyperforin has a multi-directional mechanism of action. It acts on ligand-gated

John’s Wort, thus activating brain neurotransmission and counteracting depression. Other scientists argue that hyperforin and hypericin concentrations in common supplement dosages are too low to penetrate the brain deeply enough to influence brain neurotransmission (Enna and Norton). Experimental conclusions do little to clarify. One study, quoted by scientist Amitara

Evaluation of preclinical and clinical evidence of a common herbal medicine, St John’s Wort, for mild to moderate depression. Bilal Darwish – Abstract, Active constituents, Mechanism of action, Quality standards, Safety, Side Effects, Contraindications, Interactions. Christine Nguyen–Abstract, Pharmacognostic characteristics, Parts used, Products in Australian pharmacy, Efficacy results from clinical trials, Summary. Word count: 1500 Abstract: Depression is common medical illness that has a significant

United States and is distinguished by its golden yellow calycles(1) . In addition, when flower buds are crushed, a reddish liquid would be exposed. This reddish liquid contains numerous compounds with biological activity such as phloroglucinols hyperforin, adhyperforin, the naphthodianthrones hypericin and pseudohypericin, the flavonoids hyperoside, quercetin, rutin, quercitrin and isoquercitrin, and the dimeric flavonoids amentoflavone(3). Oily Hypericum preparations have been used for centuries

Curcumin: Researchers have been studying on different herbs and nutritional supplements which led to the proposal for managing clinical disorders like depression .For example ashwagandha treats anxiety and brahmi is being used for the cognitive problems while colostrinin for dementia4 and ginseng has been successful in treating the sexual dysfunction .(1-4) Curcumin, is one of the ingredients present in turmeric. It is also an unconventional treatment that has been studied in the

Depression in a Herbal Clinic Understanding depression is vital in modern and stressful times. Depression is not an exclusive condition and affects people from all walks of life. From the word Depression – one can instantly visualise the “burden” (WHO, 2012) of this endemic condition. Churchill “affectionately” called it his “black dog” (WHO, 2012). Is it widely known that October 10 is World Mental Health Day? (WHO, 2014) Given the prevalence, death toll and disease burden - mental health is of