Striatum

Rooting back to the middle ages the now commonly known Huntington’s disease is the cause of death in one out of 15000 people around the globe. The disease’s existence is documented through history under many different names depending on the amount of information that was gathered through the unusual progression of the disease. The disease was referred to as Chorea initially due to the jerky movements of the patients affected by it. The first thorough description of the disease surfaced in 1872 as

diminish. When eighty percent of dopamine is lost, symptoms of Parkinson’s disease, such as tremor and stiffness, begin to appear. Body movement is controlled by inter-connected groups of nerve cells, known as ganglia. Information is received by the striatum, which works with the substantia nigra to send impulses back and forth from the spinal cord to the brain .The

Gene therapy for Parkinson’s disease (PD) is an alternative to current pharmacologic and surgical treatments; the former are limited by motor and non-motor complication, and both by lack of neuroprotection. Gene therapy offers a means to dominate two very different but equally significant, long-term obstacles for treating human diseases. The first, involving gene replacement, attempts to correct a specific genetic defect linked to a major component of the disease by expressing unmutated gene. In

Huntington's Disease Huntington's Disease is a genetic autosomal disorder which effects the brain. It affects about 1 in 20,000 individuals. The symptoms of the disease do not start to occur until after or around 40 years of age. With the onset of the disease the patient starts to gradually deteriorate intellectually, this deterioration also causes involuntary movements. Scientists have only recently found the section of the gene which causes Huntington's disease, and this is allowed them

My Favorite Exercise Devon Atkinson Neuroscience Fall 2014 The exercise I have chosen to explore is playing volleyball, something I did a lot of in high school. In order to fully break down exactly what is going on in the brain when playing the game, each aspect would need to be broken down and analyzed. In this paper I will be analyzing receiving (from the opponent or teammate) and passing the ball (to the opponent or teammate), In each of these actions, there is a certain amount of planning and

Pharmacology Report – Haloperidol http://psychrights.org/states/alaska/Matsutani/Exhibits2Motion4PrelimInj/78-24-100324ExE13.pdf http://onlinelibrary.wiley.com/doi/10.1038/sj.bjp.0700989/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298219/ deffo this http://bmcpsychiatry.biomedcentral.com/articles/10.1186/1471-244X-13-240 shove it in somewhere (tox) Discovery, structure, class and associated physiochemical properties Haloperidol is an butyrophenone class antipsychotic drug discovered in

The overall picture of neurological changes following early moderate PEE 1.1. The role of GABA signalling system in the developing brain The embryonic brain development process commences after the neural tube is closed at neurulation. Progenitor cells in the brain start to proliferate in the progenitor zone, where they transform into postmitotic cells and migrate to different brain regions. Once they reach their final destination, they start to grow their axons to make connections with other cells

CK2 is present and widely distributed in human and is essential for cell survival (Padmanabha R, 2006). It does not appear to be oncogenic by itself but it acts as suppressor of apoptosis and elevated levels have been associated proliferation and growth in normal and cancer cells (K. Ahmed 2009). CK2 appears to play an important role in memory and learning (Giraultet al. 1990) . Limbic system is involved in many emotions essential for survival such as fear, anger and felling of pleasure. The hippocampus

constant stream of stimuli they offer, pose a profound new challenge to focusing and learning” (www.nytimes.com). When a frequent social media users become profound to multitasking, they start to use a different part of their brain while learning: their striatum. This part of their brain inadequately interprets information and stores it as a habit. However, a focused learner uses their hippocampus when comprehending and learning new information. When a focused learner is being taught new information, it

Physiology of Parkinson’s Disease History and Definition In 5000 B.C., an Indian medical practice documented what they referred to as Kampatava, a type of disease that effected the movement and mannerisms of the human body. Little did they know, Kampatava would be the first known documentation of what in modern times is referred to as Parkinson’s Disease. Kampatava was logged in the Indian Arurveda, a medical journal, with a very generic list of signs and symptoms. This journal just barely touched