Surfactant

Introduction Bronchiolitis is defined by the textbook as, “a diffuse, inflammatory obstruction in the small airways or bronchioles occurring most commonly in children” (Heuther & McCance, 2012). It is an acute inflammatory disease of the lower respiratory tract that occurs most commonly in infants and is caused by infection with seasonal viruses such as respiratory synctial virus (RSV) (Zorc & Hall, 2010). Bronchiolitis often results from an obstruction of the small airways. It is the leading

Introduction: The selection of an appropriate dosage form is critical because a dosage form with poor drug delivery can make a useful drug worthless. A large percent of these new chemical entities (NCEs) in addition to many existing parent drugs often show poor solubilization behaviour which lead to poor oral bioavailability with wide intra- and inter- subject variation and present formulators with considerable technical challenges. [1] Many approaches have been meticulously explored to improve

breathing rates during normal breathing, moderate exercise, and heavy exercise. TV increased over normal breathing with both moderate and heavy exercise. Activity 3. Effect of Surfactant and Intrapleural Pressure on Respiration Chart 3: Effect of Surfactant and Intrapleural Pressure on Respiration Surfactant Intrapleural pressure left (atm) Intrapleural pressure right (atm) Airflow left (ml.min) Airflow right (ml/min) Total Airflow (ml/min) 0 -4 -4 49.69 49.69 99.38 2 -4

SECTION 1 1.1 introduction A new born baby in the family is very much awaited by all parents, but when the baby was born premature, many complications to be borne with the baby. Bronchopulmonary Dysplasia is one of the complications faced by the premature baby. Singer.L et al(1997),mentioned in United States Bronchopulmonary Dysplasia is one of the leading cause of lung disease in low very birth weight infants(VLBW). Infants with BPD had higher rates of mental retardation, associated with greater

ability to produce surfactant molecules, which contain strong hydrophilic and hydrophobic groups and also migrate to interfaces between oil and aqueous phases. Some biosurfactants, including some Rhodococcus produced surfactants that are more efficient, more degradable and less toxic than synthetic surfactants. The relevance of surfactants to biodegradation of pollutants is threefold; the cellular surfactants cause adherence of rhodococci to hydrophobic phases in two phases and surfactants lower the interfacial

In spite of modern ICU management and those specifically directed toward ARDS ranging from lung protective strategy, recruitment maneuvers and salvage therapies mortality rates of ARDS still disappointing. Up to date no pharmacological intervention that proven to be beneficial and if present it serves subgroups of ARDS patients depending on the etiology and patient’s health status. But hopes still exist and researches still going to find safe and effective treatment for ARDS patients and era nowadays

A REPORT ON THE SYNTHESIS AND SYNTHEIS CONDITIONS OF MESOPOROUS SBA-15 SILICA 1. MATERIALS: 1.1. A Surfactant: The surfactant to be used in this is a triblock copolymer: - poly(ethylene oxide) block – poly(propylene oxide) block – poly(ethylene oxide) block commonly known as pluronic 123 or P123. This substance is a structure directing agent (Kim & Stucky 2000) where P signifies that the copolymer is in form of a paste, 12 is a number multiplied by 300 to give an approximate molar mass of PPO

Experimental Methods to Measure the Contact Angle of Particles at Fluid Interfaces Name: Caiyi Mai Student Number: 250821954 Department: Chemical and Biochemical Engineering   Abstract Wettability of the particles plays an important role and is reflected by the three-phase contact angle, θ. However, the contact angle is frequently neglected in the studies. This mini review focused on the experimental methods that use to measure the contact angle of particles at fluid interface. The methods

gravity and, acting as a noncompressible liquid positive end-expiratory pressure (PEEP), reopen collapsed air spaces, or areas of atelectasis, or lung collapse. (2 and 3). With low surface tension, perfluorocarbons can function as an artificial surfactant and help reduce surface tension by maintaining a fluid interface with alveoli, preventing the lungs from further collapsing and thus improving lung compliance. As an inert fluid, perfluorocarbons are not metabolized into byproducts and are eliminated

This form of respiratory distress is commonly seen in premature newborns because their lungs are immature and do not have enough surfactant to keep the lungs open. It is seen almost immediately after birth or in the few hours following birth. Cause This decrease in surfactant causes the infant work harder to draw air into the lungs, which leads to low oxygenation to the rest of the body’s organs. The more premature the infant, the greater the chance of developing RDS; other factors include previous