PhysioEx Exercise 2 Activity 5
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2/6/24, 1:45 PM
PhysioEx Exercise 2 Activity 5
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PhysioEx Lab Report
Exercise 2: Skeletal Muscle Physiology
Activity 5: Fatigue in Isolated Skeletal Muscle
Name: Sophie Vanderkallen
Date: 6 February 2024
Session ID: session-45861d31-721e-d6b4-9d83-1407f28ddd01
Pre-lab Quiz Results
You scored 100% by answering 4 out of 4 questions correctly.
Experiment Results
Predict Question
Stop & Think Questions
When skeletal muscle twitches fuse so that the peaks and valleys of each twitch become
indistinguishable from each other, the muscle is in a state known as
You correctly answered: complete (fused) tetanus.
1
When the stimulus frequency reaches a value beyond which no further increase of skeletal
muscle force can occur, the muscle has reached its
You correctly answered: maximal tetanic tension.
2
A decline in a muscle's ability to maintain a constant level of force, or tension, after
prolonged, repetitive stimulation is called
You correctly answered: fatigue.
3
Which of the following is not
thought to be a contributing factor to the development of
fatigue?
You correctly answered: buildup of Ca
in the muscle fibers.
4
2+
Predict Question: If the stimulator is briefly turned off for defined periods of time, what will
happen to the length of time that the muscle is able to sustain maximal developed tension
when the stimulator is turned on again?
Your answer: The length of the rest period will not substantially impact the length of time for
sustained muscle tension.
1
2/6/24, 1:45 PM
PhysioEx Exercise 2 Activity 5
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Experiment Data
Voltage (v)
Stimuli/sec
Rest Period (sec)
Active Force
Sustained
Maximal Force
(sec)
8.5
120
0
5.86
0.08
8.5
120
0
5.86
0.08
8.5
120
12
5.86
0.02
8.5
120
22
5.86
0.06
120 Stimuli/sec at 8.5 V
Why does the stimulated muscle force begin to decrease over time despite the maintained
stimuli? (Note that a decrease in maximal force indicates muscle fatigue is developing.)
You correctly answered: More than one of these answers could be correct.
1
Why did the length of the intervening rest period affect the length of time the skeletal
muscle can maintain maximum tension once the stimulator is turned on again?
You correctly answered: Intracellular concentrations of ADP and P declined during the rest
period.
2
i
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