PhysioEx Exercise 2 Activity 5

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West Coast University, Orange County *

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Biology

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Feb 20, 2024

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2/6/24, 1:45 PM PhysioEx Exercise 2 Activity 5 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act5/ 1/4 PhysioEx Lab Report Exercise 2: Skeletal Muscle Physiology Activity 5: Fatigue in Isolated Skeletal Muscle Name: Sophie Vanderkallen Date: 6 February 2024 Session ID: session-45861d31-721e-d6b4-9d83-1407f28ddd01 Pre-lab Quiz Results You scored 100% by answering 4 out of 4 questions correctly. Experiment Results Predict Question Stop & Think Questions When skeletal muscle twitches fuse so that the peaks and valleys of each twitch become indistinguishable from each other, the muscle is in a state known as You correctly answered: complete (fused) tetanus. 1 When the stimulus frequency reaches a value beyond which no further increase of skeletal muscle force can occur, the muscle has reached its You correctly answered: maximal tetanic tension. 2 A decline in a muscle's ability to maintain a constant level of force, or tension, after prolonged, repetitive stimulation is called You correctly answered: fatigue. 3 Which of the following is not thought to be a contributing factor to the development of fatigue? You correctly answered: buildup of Ca in the muscle fibers. 4 2+ Predict Question: If the stimulator is briefly turned off for defined periods of time, what will happen to the length of time that the muscle is able to sustain maximal developed tension when the stimulator is turned on again? Your answer: The length of the rest period will not substantially impact the length of time for sustained muscle tension. 1
2/6/24, 1:45 PM PhysioEx Exercise 2 Activity 5 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act5/ 2/4 Experiment Data Voltage (v) Stimuli/sec Rest Period (sec) Active Force Sustained Maximal Force (sec) 8.5 120 0 5.86 0.08 8.5 120 0 5.86 0.08 8.5 120 12 5.86 0.02 8.5 120 22 5.86 0.06 120 Stimuli/sec at 8.5 V Why does the stimulated muscle force begin to decrease over time despite the maintained stimuli? (Note that a decrease in maximal force indicates muscle fatigue is developing.) You correctly answered: More than one of these answers could be correct. 1 Why did the length of the intervening rest period affect the length of time the skeletal muscle can maintain maximum tension once the stimulator is turned on again? You correctly answered: Intracellular concentrations of ADP and P declined during the rest period. 2 i
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