Zivistan PhysioEx Exercise 3 Activity 1

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9/24/23, 11:08 AM PhysioEx Exercise 3 Activity 1 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex3/act1/ 1/8 PhysioEx Lab Report Exercise 3: Neurophysiology of Nerve Impulses Activity 1: The Resting Membrane Potential Name: Zivistan Fidan Date: 24 September 2023 Session ID: session-e56709c6-24c6-7c14-3822-b605474d4296 Pre-lab Quiz Results You scored 100% by answering 4 out of 4 questions correctly. Experiment Results Predict Question Stop & Think Questions What is the approximate concentration of K inside a typical cell (intracellular concentration)? You correctly answered: 150 mM. 1 + What is the approximate concentration of K outside a cell (extracellular concentration)? You correctly answered: 5 mM. 2 + What is the approximate concentration of Na inside a cell (intracellular concentration)? You correctly answered: 5 mM. 3 + What is the approximate concentration of Na outside a cell (extracellular concentration)? You correctly answered: 150 mM. 4 + Predict Question: Predict what will happen to the resting membrane potential if the extracellular K concentration is increased. Your answer: The resting membrane potential will become less negative. 1 + What is the polarity of the resting membrane potential (voltage)? You correctly answered: negative. 1 What does it mean that the voltage just inside the membrane is negative? 2
9/24/23, 11:08 AM PhysioEx Exercise 3 Activity 1 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex3/act1/ 2/8 Experiment Data Extracellular Fluid (ECF) Microelectrode Position Voltage (mV) Control Cell body, extracellular 0 Control Cell body, intracellular -70 Control Axon, extracellular 0 Control Axon, intracellular -70 High K+ Axon, intracellular -40 High K+ Axon, extracellular 0 High K+ Cell body, extracellular 0 High K+ Cell body, intracellular -40 Low Na+ Cell body, intracellular -72 Low Na+ Cell body, extracellular 0 Low Na+ Axon, extracellular 0 Low Na+ Axon, intracellular -72 You correctly answered: There are more negative charges than positive charges just inside the membrane. The membrane of most cells, including neurons, contains passive, open, K leak channels. Given the normal K concentrations and the resultant concentration gradient, which direction would K be expected to move (diffuse) through these leak channels? You correctly answered: out of the cell . 3 + + + What effect does increasing extracellular K have on the net diffusion of K out of the cell? You correctly answered: It decreases the net diffusion of K . 4 + + + Which way would Na move across the membrane if there were open Na channels? You correctly answered: Na would diffuse into the cell. 5 + + + The membrane has open K channels, and changing extracellular K concentration results in a change in membrane potential. Changing the extracellular Na concentration does not significantly change the membrane potential. What do your results suggest about the number or state (open or closed) of Na channels in the resting membrane of a neuron? You correctly answered: Na channels are mostly closed. 6 + + + + +
9/24/23, 11:08 AM PhysioEx Exercise 3 Activity 1 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex3/act1/ 3/8
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