`BIOL-Learning Journal Unit 2
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Learning Journal Unit 2
The topic of the article is the discovery and treatment of hepatitis C. It wasn't an easy road because
science could only identify Hepatitis A and B until the twentieth century. Scientists discovered this
mutated version of the Hepatitis A and B virus in 1984, and it was not responding to treatments and
medications in the same way as the first two variants. Knowing the virus's particles and behavior enabled
scientists to begin screening blood in order to prevent the virus's spread in the future, and they were
eventually able to develop a cure that helped save the world from these deadly viruses (NIH, 2016).
Hepatitis C was not discovered and identified over night; in fact, scientists were not sure what to call this
virus for a long time, but it was named after its symptoms, which were similar to those of Hepatitis A and
B. Investigators at the National Institute of Allergy and Infectious Diseases' (NIAID) Hepatitis Branch were
finally able to identify hepatitis A virus in the 1970s, and after collaborating with the NIH Clinical Center's
Division of Transfusion Medicine, they had enough evidence that this new mysterious virus was neither
hepatitis A nor hepatitis B. The evidence and results proved that there is another virus or possibly a
variant that has yet to be discovered, because the virus caused more liver damage and had a higher risk
of chronic disease than hepatitis B. Above all, it was asymptomatic, which means that people would not
show symptoms until the virus had progressed to a chronic stage, long after they had been infected.
Scientists didn't have enough evidence and information on this new virus for the first 15 years, but
because of its similarities, it was dubbed non-A, non-B hepatitis.
Then, in 1989, scientists from Chiron, a California biotechnology company, and the Centers for Disease
Control and Prevention (CDC) collaborated on research that helped them identify the non-A, non-B
hepatitis virus, which they officially named hepatitis C virus (NIH, 2016). When we compare the above
situation to the information in Biology Chapter 21, we can see that most viruses become resistant when
they are treated with antibiotics to remove them from the immune system, and the virus's resistance
particles then reproduce and start a new variant of the virus (Rye et al., 2016). When scientists used
antiviral drugs to treat the hepatitis A and B viruses, the same thing happened. When an antiviral drug
worked inside the body, it killed most of the virus but not all of it, and the remaining particles became
resistant to the drug over time, they evolved and became strong enough to fight the drug, resulting in
the discovery of a new variant, which led to the development of new antiviral drugs, treatments, and
experiments (NIH, 2016).
Scientists worked hard to study the virus and develop vaccines for it, but soon after, a delta variant of
COVID-19 emerged, necessitating stronger vaccines than before. Finally, we cannot interfere with the
natural selection process of mutation and survival of the fittest in this case, but we can be prepared by
anticipating that new variants will emerge once any virus in our world is cured.
References:
Rye, C., Wise, R., Jurukivski, V., DeSaix, J., Choi, J., & Avissar, Y. (2016). Biology. OpenStax.
https://openstax.org/book
s/biology/pages/1- introduction
The National Institute of Diabetes and Digestive and Kidney Diseases Health Information Center.
(2016, June 9). Hepatitis C: from non-A,non-B hepatitis to a cure. Retrieved
from
https://www.niddk.nih.go
v/news/archive/2016/stor y-discovery-hepatitis-c- from-non-a-
non- b-hepatitis-cur
Rye, C., Wise, R., Jurukivski, V., DeSaix, J., Choi, J., & Avissar, Y. (2016). Biology. OpenStax.
https://openstax.org/books/biology/pages/1-introduction
The National Institute of Diabetes and Digestive and Kidney Diseases Health Information Center.
(2016, June 9). Hepatitis C: from non-A, non-B hepatitis to a cure. Retrieved from
https://www.niddk.nih.gov/news/archive/2016/story-discovery-hepatitis-c-from-non-a-non-b-
hepatitis-cure
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