Surfactants + COVID 2022 Prachi Patel

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Purdue University *

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112

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Chemistry

Date

Dec 6, 2023

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docx

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2

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Activities and Explorations: 10 points, Due Sunday Jan. 29 at 11:59 PM Intermolecular Forces and the Corona Virus Instructions: Upload your work on this page to Brightspace by typing or writing your responses and saving the file and uploading that file as a pdf. You can also take pictures of your written work and paste them in! Learning Objectives 11.2 Intermolecular Forces & 11.3 Properties of Liquids Describe applications of intermolecular forces to real world problems such as respiratory distress in infants, herbicide application and interaction with plant leaf surfaces, and water repellency of soil (or soil wetting), and COVID-19. Identify the intermolecular force(s) present between the same molecules and between different molecules – identify the strongest intermolecular forces in these interactions. Interpret molecular-level models/images in terms of the intermolecular interactions present. Goal: Explain how surfactants in hand sanitizer work to disrupt the lipid bilayer of the Corona Virus. Part A. (2 pts) You have learned about intermolecular forces and a type of molecule that we called a surfactant. Draw a surfactant molecule and label the hydrophobic and hydrophilic regions. Use the “cartoon” form of a surfactant for your drawing. Part B. The molecules that form the layer around the corona virus are surfactants molecules (phospholipids). The yellow layer in the image below is called the lipid membrane or a lipid bilayer because there are two layers of surfactant molecules. Using the cartoon form of a surfactant molecule, draw the lipid membrane or lipid bilayer. (2 pts.) Your drawing must have at least 8 surfactant molecules in it and it can be straight, it doesn’t have to be curved or rounded like the image. You also need to know that the environment on the inside and outside of the lipid bilayer is mainly composed of water, so how you orient the surfactant molecules matters! (2 pts.) After you have completed your drawing of this lipid bilayer clearly label the hydrophobic and hydrophilic regions of your bilayer.
Part C. Imagine your hands covered with thousands of corona viruses because you’ve come into contact with someone who is infected. You have listened to the warnings to wash your hands frequently or to use hand sanitizer frequently to keep your hands clean. Soap and hand sanitizer have surfactant molecules that interact with the bilayer and disrupt the interactions between the molecules. This opens the bilayer, the genetic material in the image above pours out, and the virus is inactivated! (2 pts) Please draw how the surfactant molecules from the soap or hand sanitizer interact with the bilayer and disrupt it. (2 pts) Explain in words and use your drawing as evidence to support your explanation how intermolecular forces allow the molecules in the lipid bilayer and the surfactant molecules in soap and hand sanitizer to interact, thus opening the bilayer. When the soap and hand sanitizer get into the body, the hydrophobic tails of the surfactant molecules try to avoid water. Thus, they interact with the lipid bilayer and wedge themselves by breaking the intermolecular forces. This allows the bilayers to open and break which disrupts it from doing its functions. The genetic material of the virus gets out eventually which inactivates the virus. Then, the soap/hand sanitizer traps the fragments of the virus away by having the hydrophobic tails in the inside, They are washed away in water.
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