Ch12_CYU Questions_Daigle

.docx

School

Valencia College *

*We aren’t endorsed by this school

Course

2010C

Subject

Medicine

Date

Apr 3, 2024

Type

docx

Pages

Uploaded by bunnielover948

Origins of Antibiotics  What was the contribution of Alexander Fleming to antibiotic research?  What is the difference between an antibiotic , a semisynthetic drug , and a synthetic drug ?  What is a prophylaxis ? Spectrum of Antibiotic Activity  What is the difference between a narrow-spectrum and a broad- spectrum drug?  Which type of drug is most desirable for use in the human host?  What complications can arise when broad-spectrum drugs are used for a long period of time? Characteristics of An ideal Drug  What are some characteristics that clinicians look for in a chemotherapeutic agent? Issues With Antibiotic Treatment  What three (3) factors should always be considered when determining the course of antibiotic treatment?  How might patient history be useful in determining whether or not to use a given antibiotic? Mechanisms of Drug Action  What are the five (5) mechanisms of inhibition for chemotherapeutic agents?  Which mechanisms are the least harmful to the human host? Why?

Drugs That Inhibit Cell Walls  Why are penicillin and cephalosporin both effective inhibitors of peptidoglycan? What advantage does cephalosporin have over penicillin in the human host?  What is the most common use for vancomycin in the clinical setting?  Why is isoniazid considered one of the most narrow-spectrum drugs? What microbial infection is isoniazid useful against? Drugs That Inhibit Protein Synthesis  Why are tetracycline , streptomycin , and erythromycin selectively toxic to bacteria and not humans?  Why is tetracycline rarely prescribed today, but erythromycin so commonly prescribed?  What one species produces over half of all the antibiotic currently used today? Drugs That Inhibit Folic Acid Synthesis  Why is trimethoprim selectively toxic to microbes despite the fact that we also need folic acid to make DNA and RNA nucleotides?  Why are trimethoprim and sulfamethoxazole often given together, rather than separately? Drugs That Inhibit Cell Membranes (Lipids)  Why are polymixins selectively toxic to Gram-negative bacteria, and not Gram-positive? Drugs That Affect Fungal Cell Membranes  Which drug is most commonly used to treat systemic fungal infections around the world?

Your preview ends here

Eager to read complete document? Join bartleby learn and gain access to the full version

Access to all documents
Unlimited textbook solutions
24/7 expert homework help