Provide a brief description of the business, state why you consider it to be “Entrepreneurial”; explain how the business creates value through the identification and exploitation of new products, processes and/or markets.
Medsaic Pty Ltd is an Australian biotechnology company that is a good example of a successful start up entrepreneurial business. Founded in 2003, as a spin-off company from the University of Sydney, it was established to commercialize patented intellectual property covering the use of microarrays for the diagnosis of disease[1].
Medsaic developed new platform technology, now known as DotScanTM, which is a solid-phase cell-capture assay using an antibody mircoarray to immunophenotype cancer cells[2], as well as
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Medsaic Pty Ltd is a good example of an Australian entrepreneurial business. They have been able to successfully develop laboratory research into a marketable product, generating value through the identification and development of a new product. They also are continuing the innovative process by researching and developing new applications for their DotScanTM platform technology, which will hopefully lead to the introduction of further products into the marketplace
Bibliography
1. Medsaic Pty Ltd 2006, Medsaic Pty Ltd, Sydney, Australia, viewed 25th of March 2009, http://www.medsaic.com
2. Major Achievements in Cancer Research, Cancer Research Network – The University of Sydney, viewed 26th of March 2009, http://www.cancerresearch.med.usyd.edu.au/research/achieve.php
3. In Dialogue Series – Jeremy Crisp 2006, podcast, Successful Innovation Podcast, 11 April, accessed 26 March 2009, http://cdn4.libsyn.com/successfulinnovation/SIP_In_Dialogue_Jeremy_Chrisp_Medsaic.mp3?nvb=200903 30005636&nva=20090331010636&t=0fb248e2383fd332872e0
4. Medsaic Pty Ltd – Company - Profile, Medsaic Pty Ltd, Sydney, Australia, viewed 25th of March 2009, http://www.medsaic.com/company.html 5. 6. Beran, R. 2005, Mayne first to offer Medsaic’s DotScan as leukaemia test, 23 August, Australian Life Scientist, viewed 27th March 2009,
Slowly he became market leader for that product. Entrepreneurship has been defined by several researchers as the progression of making a product or service valuable by gathering a distinctive set of resources and opportunities. This procedure comprises the set of accomplishments to recognise opportunities, business classification, evaluation and obtaining the essential resources, management and getting positive results. Furthermore, entrepreneurship has been seen as an organizational coordination that underlines the three extents: innovation, taking calculated risks and proactive orientation. There are many indications to provision the idea that the businesses which were engaged in entrepreneurial practices have been most effective and successful (Hills, Hultman & Miles, 2008).
1. Introduction and Problem Statement: Cancer has a major societal impact in the United States and across the globe. In 2015, an estimated 1,658,370 new cases of cancer will be diagnosed in United States, and 589,430 people are estimated to die of the disease. Unfortunately, low cancer cell availability in human samples is a current barrier for early disease detection. There is an unmet medical need to improve methods of early cancer detection so that patients can receive treatment before cancer metastasizes to other areas of the body, resulting in better health outcomes.
Oncotarget is the home of winners. The authors and researchers have received accolades for their outstanding work in medical research. Their contribution has been magnificent, with Alexander Varshavsky, Michael N. Hall. Stephen J. Elledge, and Bert Volelstein winning the Breakthrough Prize since 2013 - a top award for medical researchers. With the information they provide, Oncotarget will help people remain cancer-free. It gives people the opportunity to learn for free about cancer-related issues.
Biomarkers are natural indicators in the body that respond noticeably to the presence of disease. By measuring the responses of biomarkers, oncologists detect the cancerous cells before recommending expensive procedures, rather than immediately resorting to these procedures. One of these biomarkers that responds to the presence of cancerous cells is microRNA. MicroRNAs are molecules that are involved in the cell life cycle and therefore the progression of cancerous cells. A study in cancer patients was conducted to compare the accuracy of screening with microRNAs to screening with LDCT. Observing microRNAs did not prove to be as accurate at identifying cancer as LDCT, but since using microRNAs is a less expensive process, it can identify patients that should undergo LCDT testing. Screening with microRNA testing initially would decrease the number of patients paying for LCDT testing.
Every organization has the opportunity to maximize their return by how they strategically fit themselves in their respective market place and by how they manage the internal assets to maximize their utilization. InVentiv Health is a Contract Research Organization (CRO) that provides support for commercialization, preclinical research, clinical research and clinical trials management within the pharmaceutical industry. InVentiv Health specializes in clinical trial services and offers their clients the expertise of moving an asset, drug or device through the FDA approval process, from conception to
The scientists discovered that they can destroy the cancerous tumors using the medicine “EBC-46”, which comes from the seeds of the fruit of the tree called “Australian blushwood”. This rare tree grows only in specific areas in the northern part of Australia.
Globally, cancer is one of the leading causes of death (Fitzmaurice et al., 2015; WHO, 2012). It is continue to consider as a pandemic disease, take into account it's increasingly prevalence rate worldwide (Jacox, Daniel & Payne, 1994; American Cancer Society, 2015).
Academic research on how to improve health of humans has increased over time for treatments of various diseases and virus infections. In particular, there has been a surge in the people being diagnosed with cancer. The global scourge comes in some ways and research has shown that early detection can limit its spread in humans and work towards the cure.
Therefore, patients can receive treatment before cancer metastasizes to other areas of the body, which is resulting in better health outcomes. The main challenge in circulating tumor cell (CTC) research is their detection, which requires the ability to detect one CTC out of almost 1 billion normal blood cells [2, 3]. Based on the known properties of tumor cells, several platforms for CTC detection have been developed. Such platforms can be classified into two major categories: (I) Immunochemistry-based methods, and (II) physical property-based methods. CELLSEARCHTM from Janssen Diagnostics is considered the most successful and the only FDA-approved platform for CTC detection in clinical practice in patients with breast, prostate, and colorectal cancers. Limitation of this method is the low yield of CTC capture from larger blood volume. Metastasis often involves epithelial-to-mesenchymal transition (EMT) of cells; thus, epithelial marker-dependent approaches may miss numerous CTCs that have low or absent epithelial marker expression. Isolation by size of epithelial tumor cells (ISET) [4] is another widely accepted size-based approach. This platform applies a specific membrane filter for tumor cell selection, because tumor cells are often larger and stiffer than blood cells. Main advantage of using membrane filter is that cells can be retained for further investigation. Nonetheless, the sizes of tumor cells may vary
Globally carcinoma ends up in one.38 million deaths, creating it a number one explanation for mortality. In India sixty three,000 new carcinoma cases area unit reported annually [Ganesh et al., 2011]. In 2012, carcinoma killed associate degree calculable one,098,700 men and 491,200 ladies worldwide, similar to pure gold and Bastille Day of all cancer deaths in males and females, severally (Torre et al. 2012). carcinoma is that the leading explanation for cancer death in eighty seven countries in men and twenty six countries in ladies, with the latter mostly confined to high financial gain countries (Torre et al., 2012) Worldwide, five-hitter of carcinoma cases were
Cancer is one of the most deadly diseases worldwide caused due to various reasons hence preventing it from spreading further as well as detecting it earlier is where LifeCare Solutions plays a major role in detection of circulating tumor cells using the proposed device.
With further reading, as identified by the World Health Organization, cancer disease is a primary cause of tragedy globally, accounting for 8.2 million deaths in 2012 (2015). The most common of cancer mortalities are cancer of the lung, liver, stomach, colorectal, breast, and esophageal cancer (WHO, 2015). Moreover, one of the global burdens of disease is
Explain and critically analyze unique traits of an Entrepreneur, discuss these related to personal strengths and weaknesses
The research and development of the pharmaceutical industry is very important as the industry relies on it to develop new products to maintain and sustain the growth of the industry (ALRC 2014). According to the Australian Government Law Reform Commission, every year, the total spending in research and development in pharmaceutical industry, which includes drug discovery, pre-clinical testing and clinical trials on drugs is around $300 million (ALRC 2014). Mergers and acquisitions are intensifying in the global pharmaceutical industry, especially over the last 10 years. With factors like exorbitant research and development costs, the relatively shorter product life cycles, and the rarity of discovering a new life-changing drug acting as catalysts, leading pharmaceutical companies now have more cause to step out and look for external collaboration. This results in an increasing number of smaller biotechnology companies merging with bigger pharmaceutical companies (The
over at least the last six years. The recent acceleration in the projected growth rate for