Acute Leukemia

Leukemia, a word that means white blood, is a form of cancer that affects exactly what its name says; the white blood cells in your body. There are many different types of leukemia; some types are more common in adults, while some types are found mainly in children. Leukemia can range in severity and can affect people of all ages. During this paper we are going to explore the anatomy of leukemia, as well as the physiology. We will also learn about the statistics behind this disease, and any possible treatments.

Scenario: John is a 4 year-old boy who was admitted for chemotherapy following diagnosis of acute lymphoblastic leukemia (ALL).  He had a white blood cell count of 250,000.  Clinical presentation included loss of appetite, easily bruised, gum bleeding, and fatigue.  Physical examination revealed marked splenomegaly, pale skin color, temperature of 102°F, and upper abdomen tenderness along with nonspecific arthralgia.

Leukemia is a type of cancer that sadly causes around 25,000 deaths in the U.S. each year. The area that it affects is the blood and the bone marrow and like most or all of the types of cancer in the world if not taken control of early it will most likely kill you.

Leukemia is cancer in the bone marrow and the lymphatic system and affect the body's blood-forming tissues. Leukemia usually involves white blood cells. Your white blood cells fight off infections. People with leukemia, the bone marrow produces abnormal white blood cells, which don't function properly. Scientists don't understand the exact causes of leukemia. It is believed to develop from a combination of genetic and environmental factors. In general, leukemia is thought to occur when blood cells acquire mutations in their DNA. The CD34 phenotype. Certain abnormalities

Leukemia is a cancer that affects the bone marrow. The bon marrow is the soft spongy center of the bone that produces blood cells. Leukemia is found in white blood cells or leukocytes. The white blood cells help to fight ff infections and other diseases. Normally, cells produce in an orderly way, but people that have leukemia the cell production gets out of control. The marrow produces too many immature white blood cells called blasts. They are differently shaped and can’t carry out their usual duties.

Chronic myeloid leukemia (CML), as with all leukemia, is a cancer of the blood cells, in which normal/healthy cells are replaced by malignant cells. CML occurs through a specific chromosomal abnormality

Most of blood cells (red, white blood cells and platelets) are developed from bone marrow in normal and control condition. In body functions of blood cells is: white blood cells are required to resist infection; red blood cells are necessary to prevent anemia and platelets keep the body safe from easily bruising and bleeding. In leukemia, abnormal production of blood cells from bone marrow occurs; treatment of which is possible by bone marrow replacement. Many types of leukemia such as chronic myelogenous leukemia, acute myelogenous leukemia, chronic lymphocytic leukemia and acute lymphocytic leukemia are there

Acute myeloid leukemia (AML) also known as myelocytic, myelogenous, or non-lymphocytic leukemias. is a type of cancer of the myeloid of blood cells, developed by the expeditious growth of white blood cell, build up in the bone marrow and it also restricts the production of normal blood cells. its probability of occurrence increases with the age, normally found in adults older than 55 years of age and overall survival rate of patients those are affected with AML is 20% at 5.

Acute myeloid leukemia (AML) is characterized by an increase in the number of myeloid cells in the marrow and an arrest in their maturation.(1) Make sure you use the ASM system for reference citation; I do not believe this format you have is correct. The symptoms of AML are caused by the replacement of normal bone marrow with leukemic cells, which causes a drop in red blood cells, platelets, and normal white blood cells.(2) These symptoms include fatigue, shortness of breath, easy bruising and bleeding, and increased risk of infection.(1) Several risk factors and chromosomal abnormalities have been identified. AML progresses rapidly and is typically fatal within weeks or months if left untreated. This disease is a heterogeneous clonal disorder of haemopoietic progenitor cells.(2) These cells lose the ability to differentiate normally and to respond to normal regulators of proliferation.(2) AML has a terrible prognosis, with only 23.8% of patients surviving five years after diagnosis. (3) AML is treated initially with chemotherapy aimed at inducing a remission; patients may go on to receive additional chemotherapy or a hematopoietic stem cell transplant. The majority of patients, despite reaching complete remission with classical chemotherapy, will relapse.(3) The persistence of malignant cells is what causes remission. (3) Acute myeloid leukemia affects both older and younger patients. However, most patients are older than 60 years old, and the prognosis is worse for

Leukemia is caused by mutations in the bone marrow cells. The cell does not develop properly into a normal mature white blood cell, and becomes cancerous. Abnormal white blood cell is unable to perform its functions. At the same time abnormal cells begin actively proliferate. As a result, the number of cancer cells increases, and they begin to displace healthy cells. This leads to anemia, bleeding, and infection.

Acute Lymphocytic Leukemia is a scary disease. The term “acute” means the disease can quickly spread and progress quickly and can prove fatal in months if left untreated. “Lymphocytic” simply means that it develops from immature forms of lymphocytes. Also known as Acute Lymphoblastic Leukemia, or ALL for short, it is a type of cancer that starts from the early form of white blood cells called lymphocytes in the bone marrow. ALL is the most common form of cancer in children, though adults can get it as well. For children, treatment results in a good chance of a cure. Adults have a significantly smaller chance of a cure with ALL. ALL generally invades the blood very quickly and has the potential to spread to other body parts such as the spleen,

Acute myeloid leukemia (AML) is a type of cancer that is defined by permeation of the bone marrow, blood, and other tissues by proliferative, clonal, abnormally differentiated, and occasionally poorly differentiated treated cells of the hematopoietic system(1). The dynamic interaction between leukemia cells and the bone marrow microenvironment is one of the characteristics of leukemia. The important components of the bone marrow environment include tumor cells, extracellular matrix, non-tomur cells (fibroblasts, stromal cells, immune cells) and hypoxia(2). It is well- known in solid tumors that the excessive proliferation of tumor cells causes a severe hypoxia, which can lead to tumor progression. In the hematologic malignancies, there is the

Leukemia is a malignant cancer in which abnormal cancer cells are produced in the bone marrow (American Cancer Society, 2014) . Bone marrow is the soft, inner part of bones, such as the skull, shoulder blades, ribs, pelvic (hip) bones, and backbones. The bone marrow consists of blood stem cells, fat cells, mature blood-forming cells, and tissue that support cell growth. Leukemia is the production of abnormal white blood cells- which fight off infections (). In the bone marrow, the process of the blood stem cells developing into new blood cells is when the cells become either lymphocytes ( a form of white blood cells) or other blood-forming cells, otherwise known as myeloid cells. The other blood-forming cells develop into white blood cells,

Leukemia is a cancer of the bone marrow, a malignant progressive disease in which the bone marrow and other blood-forming organs produce increased numbers of immature or abnormal leukocytes. These suppress the production of normal blood cells, leading to anemia and other symptoms.

Cancer is a deadly disease of uncontrolled cell division and has the potential to invade or spread to other parts of the body and affects normal functioning of the vital organs. Nowadays cancer is considered as leading cause of human death in all over the world and its burden will continue to increase due to continuous growth and ageing of world’s population (Chandra, 2012). Leukemia is one of the major types of cancer, affecting significant segments of the human population, especially children and adolescents. Based on diagnosis the most commonly forms of leukemia are acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia and chronic lymphocytic leukemia (Goswami et al., 2014). Previously, it has been well documented