Analysis Of Charcot 's Joint ( Neuropathic Arthropathy )

The body tends to deal with this imbalance by filtering out excess glucose throughout the kidneys, resulting in high levels of sugar in the urine. As glucose level rises the kidneys over-whelmed and don’t function normally. They lose their ability to absorb much water the result is frequent urination. This is commonly the earliest sign of diabetes. It is often followed by unquenchable thirst as the body tries to regain the lost fluids. It often seems that more fluid comes out than went in.

The disease may cause similar changes in the blood vessels of the kidneys. This condition, called diabetic nephropathy, may lead to kidney failure. The nerves may also be affected by diabetes. This complication, known as diabetic neuropathy, can result in loss of feeling or abnormal sensations in different parts of the body.

But if it’s not taken care of, uncontrolled diabetes can damage a persons’ vision, cause nerve damage and infections to the feet. Also, it can cause poor blood circulation and kidney disease. Many of these problems can be prevented by having a low fat, low alcohol diet, maintaining a reasonable body mass, and working out thirty minutes five days a week. Performing these activities can also help reduce the risk of getting diabetes.

Frequent urination leads to excessive water loss and dehydration, which seriously jeopardizes health. Being extremely thirsty is another symptom. A person becomes thirsty because of the loss of water through urine. Excess sugar concentrates the blood, which also triggers thirst. Fatigue occurs because glucose is unable to be effectively used as a fuel by muscle cells. They are "fuel deprived" and are less able to perform work. Dehydration also causes fatigue. Weight loss is another symptom of a diabetic. It may be slow or rapid. Lots of people with early diabetes actually eat more and still continue to lose weight. This is due to the amount of water loss and the increased breakdown of fat and protein tissues, as the body makes up for poor glucose utilization. Hunger is also a symptom because glucose is unavailable to cells as fuel. Blurry vision develops as the rapidly rising blood sugar levels cause fluid shifts in the lens of the eye. Lastly, infections of the gums, bladder, skin, and vagina become harder to treat. This is

Long-term effects of diabetes can cause many serious complications: heart disease, stroke, blindness, amputations, and kidney disease and nerve damage. These complications are usually progressive and develop over time due to poor control of blood glucose levels. High blood glucose levels cause a narrowing of all the vessels, blockage, and high blood pressure.

Diabetic Ketoacidosis (DKA) is a serious disease with complications that may have fatal results in some cases. DKA is defined as an insulin deficiency that occurs when glucose fails to enter insulin into muscles such as: liver and adipose tissue. When there is an accumulation of ketones, it leads to metabolic acidosis which causes nausea and vomiting, as a result fluid and electrolytes are loss (Gibbs). There are many complications of diabetic ketoacidosis, some of the most prevalent are: Cerebral Edema, Hypolglycemia, and Acute Pancreatitis.

Moreover, older adults are twice as likely to have poor glucose control, as measured by a

According to National Kidney Foundation (2010), the majority of people with diabetes tend to develop kidney disease. This is probably the result of poor or improper dietary and life-style practices, although genetics seem to be a factor. This makes it the single leading cause of kidney failure. High blood pressure/Hypertension is another pre-disposing factor of kidney failure. This disease is also aggravated by improper dietary and life-style practices. High blood pressure/Hypertension speeds up the loss of kidney function and eventually leads to kidney failure. It also appears to have genetic and familial factors (National Kidney Foundation, 2010).

Diabetic nephropathy is damage to the small blood vessels in the kidneys (William & Hopper, 2011). This is most often due to long term diabetes mellites which can and will cause kidney failure (William & Hopper, 2011). The high blood sugar for diabetes causes the blood vessels to become constricted (William & Hopper, 2011).

In lecture and lab, we learned that having too much glucose in the blood can be harmful to the body. Through research, I found that too much glucose in the blood can cause neuropathy and kidney damage. Neuropathy is damage to one of the peripheral nerves, causing numbness and weakness. One of my family members suffered from neuropathy due to diabetes. Her feet and part of her legs had turned purple and she could hardly walk because of the numbness and the pain. Another result of too much glucose in the blood is kidney failure. Kidney failure happens when the kidneys are unable to remove waste and balance fluids. People that do have kidney failure are put on a dialysis machine. A dialysis machine basically acts as the person’s kidneys, filtering and balancing the blood. A close family friend was put on dialysis because his diabetes became out of control. He was hospitalized numerous times because he failed to go to his dialysis appointments, proving that too much glucose in the blood can be

This is because the kidney contains many blood vessels, and any disease that damages these also affects the kidney. It is also known that even mild cases of high blood pressure or having slightly elevated blood sugar levels can still increase a person’s risk for kidney problems. Managing these conditions helps minimize the risk of damage to these critical organs.

Kidney disease and diabetes tend to go hand in hand as the kidneys of diabetics slowly thicken and become progressively scarred over time. The nephrons, which are the basic functional and structural units of the kidneys, become leaky and allow albumin, a protein made by the liver, to pass freely into the urine. The damage to the kidney may be ongoing for many years before a patient becomes symptomatic and loses the ability to filter the blood, control the fluid balance of the body and remove waste products.

CAUSES OF ALBUMINURIA High blood pressure, Congestive heart failure  Metabolic syndrome, or kidney damage from nephrotic syndrome ALBUMINURIA is seen in all forms of acute and chronic renal diseases GLUCOSE Glucose is found in the blood and is the main sugar that the body manufactures Glucosuria- The presence of glucose or blood sugar in urine is. It may indicate that the person has diabetes. Diabetes Mellitus -  condition in which the pancreas no longer produces  enough insulin or cells stop responding to the insulin that is produced, so that glucose in the blood cannot be absorbed int o  the cells of the body. SYMPTOMS OF DIABETES MELLITUS  frequent urination increased thirst  increased hunger The treatment includes changes in diet, oral  medications, and in some cases, daily injecti ons of  insulin.

One of the diseases is diabetes mellitus which is a major cause of renal failure. This disease can be defined as an increase of fasting blood glucose that is affected by a deficiency in insulin hormone. The normal range for glucose (fasting) in the blood is 2.8-6.0 mmol/L. It is classified into two groups, type 1 (insulin-dependent diabetes mellitus) and type 2 (non insulin-dependent diabetes mellitus). Stein (2008, p.6) points out that kidney failure happens most often when patients have suffered from diabetes mellitus for more than 10 years. According to United States Renal Data System (USRDS) report in 2007, approximately 44% of primary causes of renal failure is diabetes mellitus in the United States in 2005. Also, Stein (2008) indicates that 15% of dialysis patients are influenced by diabetes mellitus in the United Kingdom. Diabetes mellitus has negative affects throughout the kidneys where the increase of the range of blood sugar causes the damages to the cells in the kidneys. This leads to the presence of the glucose in the urine which is known as glycosuric.

The most common symptoms of diabetes mellitus are chronic elevated blood glucose level. Glycosuria is a condition in which the kidneys excrete increased glucose as they are unable to reabsorb the excess amount. This leads to fluid and electrolyte excretion which leads to electrolyte imbalance and dehydration. Loss of glucose leads to increase in the use of fats and protein for the energy, which leads to accumulation of ketone bodies in the blood which leads to ketoacidosis (could be fatal).