Cancer Is The Uncontrolled Growth Of Cells, And Is A Major Cause Of Death Throughout The World

In women, one of the most common cancers of course is breast cancer, in men prostate cancer and in men and women, lung cancer and colon cancer are common cancers. It is important to understand that the cancer that occurs in one individual is very different from the cancer that occurs in another. Everyone is different; a lung tumor in one person will be different from a lung tumor in another person. Once a diagnosis of cancer is made, the next obvious question is what do you do? There are several things that are really relevant, for example, the stage of the cancer which is information about where is the cancer?

Cancer results from abnormal, unregulated cell growth which can create physiological impairments in body tissues (1). Two adverse characteristics of cancer cells include the ability to invade other tissues and the inability to die (2). Cells generally become cancerous due to changes in gene expression and subsequent errors in protein function (2). These faults in genes and physiology can be caused by mutations which can result from exposure to carcinogens. One of the most common substances associated with carcinogens (though not carcinogenic itself) that promotes cancerous growth is nicotine (3). Nicotine has been shown to stimulate growth, promote the creation of blood vessels (angiogenesis), and prevent cell death through nicotinic acetycholine receptors (nAChRs)(3). In mice, for example, nicotine increased levels of angiogenesis by altering mechanisms involved in a heightened response of the COX-2, prostacyclin, VEGFR-2, MMPs, uPA, and e-NOS protein activity (3). These increases in cell sensitivity to these particular factors stimulated by nicotine promoted cell growth and migration to other tissues (3).

Mild toxicity has symptoms of lacrimation, eye pain, irritation of the mucus membrane, hoarseness, swelling of the skin, sneezing, and coughing. Severe toxicity’s symptoms include blindness, blistering, vomiting, nausea, and respiratory complications. Lung injury was the leading cause of death after the exposure of mustard gas. Lung injuries start with mild symptoms, and slowly increase into chemical pneumonia, and pulmonary edema. Within twenty-four hours of exposure to skin, victims are itchy and skin irritation, which lead to yellow filled blisters. Five to ten days after the exposure of large amounts of mustard gas, there is a drastic reduction in white blood cells. The decrease of white blood cells, affect the bone marrow and lymphatic tissue to look as if the person was exposed to radiation. The best treatment is decontamination.

Treatment: Chemotherapy has also changed throughout the years. During World War 2, a compound called nitrogen mustard was found to work against Hodgkin’s disease. This compound was the first effective cancer fighting agent, but many more effective medicinal

In the 1940s, two Yale pharmacologists, Alfred Gilman and Louis Goodman, studied the beneficial effects of mustard agents in helping lymphoma. It was not first made to be a cancer treatment. They injected a type of mustard gas into a patient who had Hodgkin’s lymphoma. They found that the patient's tumor masses had lessened after just a few weeks of treatment. Since then, Chemotherapy started to gain

Cytotoxic chemotherapy was first discovered during World War II by Gilman and Philips when they perceived the effect that nitrogen gas (used during WWI) had on the number of human cells proliferating and recognised this as a potential treatment for cancer. From this discovery, biotherapy was born helping to increase our knowledge in how to achieve cell death and tumour control through use of cytokines and monoclonal antibodies (Young et al, 2006). Cancer is often described as unregulated cell growth through a multistep process (Brighton et al, 2005). Brighton (2005) describes the ‘Hallmarks’ of the cancer cell as needing to acquire these six steps in order to develop: ‘self-sufficiency in growth signals, insensitivity to antigrowth signal, avoiding apoptosis, limitless replicative potential, angiogenesis and tumour invasion/ metastasis’. These six Hallmarks of Cancer describe the pathogenesis that a cell undertakes until it develops into a tumour which can then potentially become malignant (Hanahan et al, 2011). While normal cells can control their own proliferation that allows a homeostasis amongst cells, that new cells are born once the old cells have died ensuring that there are enough cells available to fulfil the task at hand. Cancer cells are more neurotic, they interrupt the normal signalling pathway within the healthy cells, and then they begin to grow uncontrollably invading the

Cancer is one of the leading causes of death worldwide as it can develop in almost any organ or tissue. Significant advances in understanding the cellular basis of cancer and the underlying biological mechanisms of tumour has been vastly improved in the recent years (Jiang et al. 1994). Cancer is a genetic disease which requires a series of mutation during mitosis to develop, its characteristics can be associated with their ability to grow and divide abnormal cells uncontrollable while in the mean time invade and cause nearby blood vessels to serve its need. Even though many people are affected by cancer today, the abilities which cancer cells have make it hard to find a single effective treatment for cancer. The focus of research now lies

As gas or fluid, mustard agents strike the skin, eyes, lungs and gastro-intestinal tract. Inside organs may be hurt as a delayed consequence of mustard agents being taken in through the skin or lungs and travel on into the body. The postponed impact is a normal for mustard agents. Mustard agents give no prompt side effects upon contact and thus a postponement of somewhere around two and twenty-four hours may happen in advance of agony is felt and the casualty gets to be aware of what has happened. By then cell harm has as of now been created. Intense mortality emerging from introduction to mustard agents is low. The dosage expected to specifically kill a man upon inward breath speaks the truth 50 times more than the measurement mortality by harming somebody with the nerve agent soman. People who kick the bucket after contact to mustard agents routinely do as such following a couple of days up to one or more weeks. While the most thorough wounds are brought about after contact with fluid mustard agents. Skin inflammation first appears as a difficult irritation. Contingent upon the caliber of exposure, the damage may form into pigmentation, which flakes off around two weeks, minor surface blister or profound fluid filled blisters may form resulting in skin rot. In astonishing cases, the skin rot may be so extensive to the point that no blisters appear. Skin wounds are more

Cancer is a disease of the cells, Inside all cells are coded instructions for making new cells and controlling how cells behave. These coded instructions are genes. Abnormal changes in genes can turn normal ovarian cells to cancer cells. Normal cells grow and divided to make new cells. New cells are made as the body needs them to replace injured or dying cells. When normal cells grow old or get damaged, they die. Cancer cells don’t do that. The changes in genes causes cancer cells to make too many copies of themselves (National comprehensive cancer network,2015).

Throughout recorded history, cancer has been a subject of investigations. Lacking current surgical technique and diagnostic procedures and lab equipment, the scientists relied on their sense to determine the disease including its treatment. So the scientist began to describe the cancer in some theories which what I’m going to describe them below.

Cancer is the leading cause of death in economically developed countries and the second leading cause of death in developing countries. (Organization, 2004) The burden of cancer is increasing in economically developing countries as a result of population aging and growth as well as, increasingly, an adoption of cancer-associated lifestyle choices including smoking, physical inactivity, and “westernized” diets. In this article, we provide an overview of the global cancer burden, including the estimated number of new cancer cases and deaths in 2008 and the incidence and mortality rates by region for selected cancer sites. These statistics are based on GLOBOCAN 2008, the standard set of worldwide estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer (IARC) for 2008. We comment on the recent incidence and mortality patterns observed for a number of common cancer forms, alongside established preventive measures that can reduce the worldwide cancer burden. (Jemal, et al., 2011)

Cancer is one of the leading causes of morbidity and mortality worldwide, with approximately 14 million new cases in 2012.2 The amount of new cases is expected to rise by about 70% over the next 2 decades. Cancer which causes nearly 1 in 6 deaths, is the second leading cause of death globally, and was responsible for 8.8 million deaths in 2015. Approximately 70% of deaths from cancer occur in low- and middle-income countries. In 2012 about 14.1 million new cases of cancer occurred globally (not including skin cancer other than melanoma).3 The most common types of cancer in males are lung cancer, prostate cancer, colorectal cancer and stomach cancer.

“Cancer is the abnormal, uncontrolled multiplication of cells” (Fahey, 2015). There are many different kinds of cancers that affect various parts of the human body. Some of the most common types of cancer include lung cancer, breast cancer, and prostate cancer. Cancer, of all types, is one of the leading causes of death across the world today with Denmark and France being the countries with the highest rate for all cancers (World Cancer Research Fund International, 2012). “The lifetime risk of developing or dying from cancer refers to the chance a person has, over the course of his or her lifetime (from birth to death), of being diagnosed with or dying from cancer. These risk estimates, like annual incidence and mortality data, provide another measure of how widespread cancer is in the United States (American Cancer Society, 2016).” This risk for cancer is also becoming increasingly high as time goes on. According to the American Cancer Society, one in three people have a lifetime risk of being diagnosed with and/or dying from cancer (2016). The statistics of this risk varies between men and women as one gender may be more susceptible to a particular cancer than the other. Cancer can be treated in various ways and some forms are treatable whereas some are neither curable nor treatable. Here I will attempt to discuss how and/or why cancer forms, its detection, its treatment, as well as a few warning signs of some of the various forms of cancer.

One-hundred percent of us humans will all die, seventy percent will have something that attempts to take a precious life, nineteen percent of them will actually die from it, it being cancer. One walks into their specialist's office, already shaken up by the whole event of their findings, to only have a whole dictionary of medical terms thrown at them, knowing that the chance of survival is low. Though all that is happening is an uncontrolled division of abnormal cells in the body.

Skin cancer caused due to uncontrolled abnormal growth of skin cells. There is rapid multiplication of skin cells due to unrepaired DNA. The unrepaired DNA damages the skin cell in form of mutation or genetic defects and form malignant tumors.