Causes And Treatment Of Cervical Cancer

This year alone approximately 12,360 documented new cases of cervical cancer in the United States and 4,020 deaths according to National Cancer Institute (“Cervical Cancer”, 2014). Cervical cancer is a slow growing cancer that grows in the tissues of the cervix (an organ that connects the uterus and vagina). The disease is predominantly caused by the human papillomavirus infection (HPV). According to the Center for Disease Control and Prevention, the HPV virus is so common that nearly all sexually active women and men get it at some point in their lives. Many types of HPV exist, some causing genital warts and potentially cervical cancer. Individuals can get HPV by having unprotected genital to genital touching, oral, vaginal, or anal sex. Anyone who is sexually active can get HPV, and can develop symptoms years after they had sex with someone who is infected, making it difficult to know when they first became infected.

Cervical cancer is when there are malignant cells present in the cervix; it is developed in the lining of the cervix. A cervix is a narrow opening located at the bottom of the uterus that leads into the vagina. Cervical cancer mostly affects women between the ages of 40 and 55. This cancer can be prevented by screening for precancerous cells, and it can also be cured if it is detected at an early stage. Over the past few decades the number of cervical cancer cases has declined dramatically due to a more widespread screening of the disease. Today, it is estimated that 10,000 new

Cervical Cancer Early Detection Program Journal of Women’s Health 20(10):1479-84 doi: 10.1089/jwh.2010.2530. Epub 2011 Jul 20

Prophylactic vaccination against high risk human papilloma virus 16 and 18 represents an exciting means of protection against HPV related malignancy. However, this strategy alone, even if there is a level of cross protection against other oncogenic viruses, cannot completely prevent cervical cancer. In some countries cervical screening programs have reduced the incidence of invasive cervical cancer by up to 80 percent although this decline has now reached a plateau with current cancers occurring in patients who have failed to attend for screening or where the sensitivity of the tests have proved inadequate. Cervical screening is inevitably associated with significant anxiety for the many women who require investigation and treatment following abnormal cervical cytology. However, it is vitally important to stress the need for continued cervical screening to complement vaccination in order to optimize prevention in vaccines and prevent cervical cancer in older women where the value of vaccination is currently unclear. It is likely that vaccination will ultimately change the natural history of HPV disease by reducing the influence of the highly oncogenic types HPV 16 and 18. In the long term this is likely to lead to an increase in recommended screening intervals. HPV vaccination may also reduce

Cervical cancer is caused by the uncontrollable growth of cells in the cervix, the lower part of the uterus that opens into the vagina. Some signs of cervical cancer are abnormal bleeding in the vagina (between menstrual cycles, after sex, and after menopause), pain in the lower belly, pain during sex, and abnormal vaginal discharge.

Almost all cervical carcinomas are caused by Human papillomavirus (HPV). Cervical cancer can be a life-threating disease. However, over recent years the occurrence of cervical cancer has declined as well as the chance of dying from it. A huge contributing factor to this decline is the importance of a regular pap smear. A pap smear can find cervical pre-cancer before it turns into cancer. Recently, a vaccine for HPV, has been on the market, which provides close to a 100% protection against pre-cancer and general warts. HPV and cervical cancer are two disease that are closely related. However, each disease effects not only similar populations, but also different populations, as well as having its own signs and symptoms, detection procedures,

Primarily, cancer of the cervix uteri is affecting women in developing countries such as “sub-Saharan Africa, Melanesia, Latin America and the Caribbean, South-Central Asia, and South East Asia” (Parkin and Maxwell, 2006, p. 1). Given the incidence rates of the different ethnicities aforementioned by the USCSWG, there is no plausible evidence that negates a positive correlation of cervical cancer among racial ethnicities of divergent countries to the United States. To exemplify, Parkin and Maxwell (2006) suggest that the standard age incidence rate (ASR) for cervical cancer in the Caribbean is 33.5 per 100,000, the ASR for sub-Saharan Africa is 31.0 per 100,000, and the ASR for the United States is less than 15.0 per 100,000. Hariri, Unger, Sternberg, Dunne, Swan, Patel, and Markowitz (2011) remark that the prevalence of HPV in Africa-American women was high, even with just having one lifetime partner.

Cervical Cancer affects around 34000 women every year around the UK (Bupa UK, 2013). Cervical Cancer is a result of the mutation of the DNA caused by the by the Human papillomavirus (HPV), (NHS, 2013).

Cervical Cancer is the second most common cancer for women yet it is the most common cancer of the reproductive system. According to the CDC in 2010 11,818 women in the United States were diagnosed with cervical cancer and 3,939 women in the United States died from cervical cancer. The most common type is squamous cell carcinoma. Human papilloma virus, otherwise known as HPV, is known to cause cervical abnormalities and has been linked to cervical cancer.

Cervical cancer is the leading cause of cancerous death, in women, since 1950. Approximately 200,000 cervical cancer patients die each year in developing countries. Strains like HPV 16 and 18 cause about 70% of cervical cancer in women– one of the top causes of death in the world (WebMD, 2010, p.1). In the Unites States, about 10,000 women acquire the disease and 3,700 die annually Human Papilloma Virus (HPV) is directly associated as a cause of cervical cancer. This virus affects the skin and genital area and, in some cases, it can also infect the throat and mouth. Since the HPV is passed from one person to another through skin-to-skin or sexual contact, sexually active people are more prone to this virus. Merck

In US cervical cancer is ranked 13th most common cancer in women and 4th among women between 15 to 44 years.

Did you know there is more of a link between cervical cancer and HPV than smoking and lung cancer? Cervical cancer is currently the fourth most common cancer in women and the second leading cause of death from cancer in women. Along with those statistics, human papillomavirus is the most common sexually transmitted viral disease amongst men and women worldwide. The prevalence of women having a strain of HPV that ultimately leads to or increases the chance of cervical cancer is highly relatable. What is pathophysiology, signs, symptoms, prevention, and treatments of this ailment? You might ask will be covered in the next few pages of this paper.

Cervical cancer is one of the highly popular disease for the women. Different programmes has been made up to fight against this deadly disease. New Zealand has one of the best screening programmes in the world. The establishment of National Cervical Cancer Screening Programme in NZ in 1990 had reduced a significant number of 60% of women who develop cervical cancer and who die from it since it was built. More than 1 million New Zealander women are enrolled in this programme and 95 % are eligible. The Cervical Cancer screening programme aims to; informing women about the importance of having the cervical screening tests; promoting cervical screening tests on a regular basis to women aged 20–70; ensuring high-quality and culturally appropriate services; supporting women with abnormal tests; ensuring there is regular monitoring to see that the goals of the programme are being met. The NCSP also acknowledges the importance of the Treaty of Waitangi in providing a screening programme that is successful for all New Zealand women.

As many as 1,400 women in Canada are diagnosed with cancer of the cervix each year. More than 400 die from it (Mah et al, 2011).

In the United States, it is one of the eight-most common cancer of women. According to researches, the data shows that Hispanic women are significantly more likely to be diagnosed with cervical cancer than the general population and their median age at diagnosis is 48. In 1998, about 12,800 women were diagnosed in the US and about 4,800 died. Among cancers of the female reproductive tract, it is less common than endometrial cancer and ovarian cancer. The rates of new cases in the United States was 7 per 100,000 women in 2004. Cervical cancer deaths decreased by approximately 74% in the