Diabetes is a metabolic disease in which the body’s inability to produce any or enough of the hormone insulin causes elevated levels of glucose in the blood. There are different types of diabetes; Diabetes Mellitus Type I, Diabetes Mellitus Type II, Gestational Diabetes, and Diabetes Insipidus. The type of diabetes you are diagnosed with is characterized by the way the body produces insulin and how the body responds. According to the CDC 2014 Statistics Report, at present 29.1 million people in the United States have diabetes of 8.1 million of those people are undiagnosed. The ethnic groups showing the most prevalence of diabetes are Hispanics, Non-Hispanic Blacks, and Native American. The most common symptoms of diabetes are …show more content…
(Hermanns-Le, Scheen, & Pierard, 2014, p. 200) As our cells fail to respond to insulin, the beta cells of the pancreas produce more insulin and trigger the liver to produce more glucose to restore glycemic control. This compensational mechanism will eventually be unable to keep up with the body’s demands leading to elevated glucose levels in circulation. Eventually, the high demand of pancreatic beta cells to produce insulin will not be able to keep up and insulin production will become insufficient, lessening the uptake of glucose. This now opens the path to Type II Diabetes Mellitus. (Thoenes, 2012, p. 621)
Insulin resistance eventually will lead to compensatory hyperinsulinemia. When serum insulin levels become elevated, there is a more dynamic effect on cell growth. This occurs through the binding and activation of insulin-like growth factor (IGFR) receptors in the peripheral tissues. (Hermanns-Le, Scheen, & Pierard, 2014, pp. 200-201) Research suggests the elevated binding rate of insulin to IGFR causes cell growth and boosts proliferation of the epidermal and dermal cells, keratinocytes and fibroblasts respectively. (Thoenes, 2012, p. 621) Keratinocytes make up 95% of the top layer, epidermis, of the skin. They produce keratin, a protein, which gives the skin its suppleness, durability and waterproofs the surface. Fibroblasts are dermal cells which are
Type II Diabetes, also known as diabetes mellitus, is also called non-insulin-dependent diabetes or aadult onset diabetes. It is a medical disorder that, due to a number of factors codependent with the modern world, is characterized by higher than normal blood glucose levels that play havoc with insulin deficiency and resistance. Insulin resistance means that cells do not respond appropriately when there is free insulin in the blood system. Essentially, they body is reacting to an improper balance of sugars and insulin. Because obesity is often present, research suggests that even thought the mechanisms controling glucose and insulin are unclear, the adopose tissue likely
29 million people in the United States (9.3 percent) have diabetes, and of those 29 million approximately 7.25 million are unaware that they are diabetic (www.cdc.gov). Diabetes describes a group of metabolic diseases in which the person has high blood glucose because insulin production is inadequate, or because the body 's cells do not respond properly to insulin, or both. Diabetes can be divided into two groups: Type 1 diabetes and Type 2 diabetes. Type 1 diabetes is also referred to as juvenile diabetes and is usually found in children and young adults. Only 5% of people with diabetes have this form of the disease. Type 1 diabetes restricts the body from producing insulin, a hormone that is needed to convert sugar, starches and other food into energy needed for daily life. Type 1 diabetes can be managed by using insulin therapy and other treatments to help those infected maintain insulin to convert sugars, starches and foods into energy(www.diabetes.org). Type 2 diabetes is the most common, people with Type 2 diabetes have insulin resistance meaning the body does not use insulin properly. At first, the pancreas makes a surplus insulin to compensate for the lack on insulin in your body. However, over time your pancreas is not able to keep up and can not make enough insulin to keep your blood glucose at normal levels(www.diabetes.org). Complications of diabetes in the long term include potential heart disease, stroke, and kidney damage.
"The facts are clear: The diabetes epidemic sweeping the U.S. is hitting the African American community particularly hard, according to doctors." (2) Diabetes is defined as, "A disease that affects the body's ability to produce or respond to insulin, a hormone that allows blood glucose (blood sugar) to enter the cells of the body and be used for energy." (1) There are two types of diabetes: type 1 diabetes and type 2 diabetes. Type 1 diabetes, which usually begins during childhood or adolescence, "Is a condition characterized by high blood glucose levels caused by total lack of insulin. This occurs when the body's immune system attacks the insulin producing beta cells in the pancreas
For my health project topic I chose Diabetes. One of my aunts has type one diabetes, and that is partially why I chose to do this topic. Diabetes is a group of metabolic diseases in which the person has high blood glucose (blood sugar) because of varying reasons. Some of these reasons include insulin production is inadequate or because the body’s cells don’t respond properly to insulin, or both. Insulin is a hormone produced in the pancreas that regulates the amount of glucose in the blood. Basically it is a hormone needed to allow sugar (glucose) to enter cells to produce energy. The lack of insulin causes a form of diabetes. Diabetes is a long term condition that causes high blood sugar levels. People with high blood sugar have frequent urination (Polyuria) and become increasingly thirsty and hungry (Polydipsia and Polyphagia). There are three types of diabetes, Type 1, Type 2, and Gestational Diabetes. Type 1 is when the body does not produce insulin. Type 2 is when the body does not produce enough insulin for proper function. Finally, Gestational Diabetes may effect females during pregnancy.
Special cells called beta cells located in the pancreas produce a hormone called insulin. The function of insulin is to transform blood sugar, also known as glucose, taken from foods consumed into energy. Insulin moves glucose into cells where it is stored for energy use. Type-two diabetes occurs when the body is incapable of utilizing insulin properly due to the failure of appropriate production from the pancreas. This failure, called insulin resistance, inhibits blood sugar from entering the cells throughout the body and turning it into energy. The glucose is not able to enter the cells, thus creating high levels of sugar in the blood. This elevated sugar levels in the blood is also known as hyperglycemia. In an overweight or obese body, it is harder to utilize insulin correctly due to the increased body fat. Although a normal weight person can develop diabetes, the chances are greater with increased fat in the midsection of the body. A malfunctioning liver, miscommunication between cells, and damaged beta cells could also lead to diabetes. Factors
People all around the world might know someone with diabetes, but might have never realized how did they get diabetes, what will happen with them, what do they go through, what makes them change their lives, or what is there everyday basis when someone has diabetes? It may not be your problem, but to show respect and care for the one who may have diabetes can help them and benefit yourself to know more about it and have a better understanding of it. It can impact a person 's personal life to know about an issue that is world wide. The problem that is issued all over the world is Type 1 and 2 diabetes or in general diabetes. The issue or problem has impacted many people all around the world, through people’s daily life. They most likely
Diabetes is a disease caused by malfunctions in glucose metabolism. It is the malfunctioning of beta cells of the pancreas, which causes an over or under production of insulin, or the cells become insulin- resistant. The pancreas is the organ in the body located partially behind the stomach composed of millions of cells called pancreatic islets, or islets of Langerhans. These islets contain two major hormone- producing cells which are the alpha cells and the beta cells. The alpha cells synthesize glucagon and the beta cells synthesize insulin. These cells secrete glucagon and insulin, especially during the period of fasting and fed states. Glucagon and insulin are both involved in regulating blood glucose levels. Insulin is the main factor
It is not news to anyone that one of the most known disease in the world is diabetes mellitus, people with type two diabetes produces some insulin, but not enough to keep their blood sugar at a normal level, however the one that are affected by the type 1 diabetes or childhood-onset type 1 DM do not produce insulin at all. Type 1 diabetes is usually diagnosed in children and young adults, and was previously known as juvenile diabetes. (ADA, 2015) . That circumstance puts them at greater risk for heart disease, renal disease and blindness to name a few. Sadly Worldwide, the occurrence of type 1 DM has been steadily rising, representing a significant burden on the people and to the health-care systems. Although momentous improvements in the care of T1DM patients, a subsection remain in major difficulty due to stubborn hypoglycemia. The possibility of IT offers the chance of better glycemic mechanism. Currently we are observing considerable advancement in the number and results of IT phenomenal. In type 1 DM is an autoimmune disease that causes the body the destruct the b cells in the pancreas, which are responsible for the production of insulin. As a result, supplementation of insulin is a must in the management of the disease through meticulous care of multiple daily injections to control blood glucose. Even accommodating to the treatment many do not maintain a stable blood glucose level and are at risk for metabolic problems. Ultimately replacing of β cells are the only
Your grandmother on your mother’s side of the family has diabetes. Her husband, your grandfather, is at risk for diabetes. Your father has diabetes. Your mother is at risk for diabetes. Your half-sister on your father’s side of the family was recently tested for diabetes. What kind of future regarding diabetes does that leave you with?
Type II Diabetes (diabetes mellitus), is also sometimes referred to as adult onset diabetes or non-insulin dependent diabetes. It is a medical disorder that, due to a number of factors codependent with the modern world, is characterized by higher than normal blood glucose levels that play havoc with insulin deficiency and resistance. Insulin resistance means that cells do not respond appropriately when there is free insulin in the blood system. Essentially, they body is reacting to an improper balance of sugars and insulin. Because obesity is often present, research suggests that even thought the mechanisms controling glucose and insulin are unclear, the adopose
Diabetes mellitus (sometimes called "sugar diabetes") is a condition that occurs when the body can 't use glucose (a type of sugar) normally. Glucose is the main source of energy for the body 's cells. The levels of glucose in the blood are controlled by a hormone called insulin, which is made by the pancreas. Insulin helps glucose enter the cells.
The cells of a diabetic have problems taking up glucose due to either the lack of insulin or a resistance to insulin. Instead, the sugar remains in the blood, resulting in the rise of blood glucose levels. The rise in blood glucose levels results in the disease that is broken down into two main types, type one diabetes and type two diabetes. Type one diabetes is an autoimmune disease, meaning a disease in which the body 's immune system attacks healthy cells, that causes the insulin producing beta cells in the pancreas to be destroyed. The immune system, by mistake, attacks its own insulin-producing cells so that insufficient amounts of insulin are produced or no insulin at all. Type one diabetes is also referred to as insulin dependent diabetes because people diagnosed with this type of diabetes are required to administer insulin injections into themselves. The possible causes for type one diabetes are linked to genetics or environmental circumstances. The possible genetic inheritance of type one diabetes is strongly linked with HLA-DQ and DR on chromosome 6, but genetic factors on other chromosomes such as the insulin gene on chromosome eleven and the cytotoxic T-lymphocyte antigen gene on chromosome two may lighten the disease risk. Other studies support the idea that environmental factors are important. Gestational infections, or infections in the womb, may contribute to initiation, whereas later infections may accelerate islet beta cell autoimmunity. The development of
Insulin resistance takes place when there is a reduction in the sensitivity of the body to insulin. As a compensatory mechanism, the pancreatic Beta cell to produce more insulin (12, 13, 14). It may cause the Beta cell to overwork and eventually weakens. As a result, it cannot produce adequate insulin for the body and leads to the development of type II diabetes (12). In the absence of insulin, there will be an increase in fatty acids (12).
Insulin deficiency refers to when a person fails to secrete adequate levels of insulin during digestion of meals (Naseem et al., 2012). Producing adequate levels of insulin is essential for being able to overcome the increase of glucose levels in the body while eating, this is achieved by sending signals to the liver to reduce its production of endogenous glucose. However, after prolonged exposure to this disease, this affects the ability of β-cells to respond to rises in glucose levels. (Mazze, Strock, Simonson, & Bergenstal, 2004, p. 80). Located in the pancreas, β-cells, or Beta cells, are responsible for the production and storage of insulin (Resnick, 2014).
Diabetes mellitus, or simply diabetes, is a metabolic disorder that is marked by hyperglycemia, high blood glucose. In 2014, 29.1 million individuals in the United States, which is about 9.3% of the population, have diabetes . Among all cases of diabetes, about 90% to 95% are Type 2 Diabetes (T2D), the diabetes form generally results from defects in insulin action . Furthermore, other related complications of diabetes will afflict patients with their cardinal, ocular, renal, and nervous system dysfunction, mainly resulting from hyperglycemia .