Diabetes Type 2 Meta Analysis

Type 2 diabetes is often managed by engaging in exercise and following a diabetic diet. Oral medications may also be used, and in more advanced or severe cases, insulin therapy may be prescribed. The condition is rapidly increasing in the developed world, and there is some evidence that this pattern will be followed in much of the rest of the world in coming years. The Centers for Disease Control and Prevention has characterized the increase as an epidemic.

Type 2 Diabetes is a disease that is found in a variety of age groups around the world. This disease is growing at a rapid rate and it is impacting the health of this generation and future generations to come. Diabetes is a disease that impairs the body’s ability to produce or respond to the insulin hormone produced by the pancreas. The insulin allows for the glucose to be effectively used as energy throughout the body. Diabetes causes carbohydrates to be abnormally digested, which can raise blood glucose levels. This means that the glucose is not being taken up by the cells that need it. The cells cannot take up the excess glucose that has accumulated in the blood, so it is excreted through the urine. This can lead to problems with the kidneys, central nervous system, heart, and eyes because high blood glucose can damage the blood vessels of these organs. This diseased is managed by adopting a diet low in fat and high in fiber, increasing physical activity, losing excess weight, and not smoking. If this

Everybody knows that obesity is a big factor in developing type-2 diabetes, and that part of coping with this metabolic disorder is lifestyle change. If blood glucose does not go down, then medicines are introduced. Some type-2 diabetics even have to administer insulin in order to keep their blood glucose levels

Type 2 diabetes mellitus (T2D) is the most common form of diabetes (American Diabetes Association, 2012). T2D is so prevalent that it is estimated to be the fifth most common cause of death worldwide (Yates, Jarvis, Troughton, and JaneDavies, 2009, p. 1). T2D manifests when the body is unable to metabolize glucose properly, resulting in elevated blood sugar, debilitating fatigue, and other serious complications such as distal limb amputations, kidney failure, and blindness. The generally accepted causes of T2D include diet, sedentary lifestyle, and obesity.

According to Zimmet (2001), about 150 million people in the world have been suffering with diabetes and it would be 300 million by 2025. Another interesting study by AusDiab in 2000 revelead that 7.4% of the population aged 25 or over had diabetes (type 2 in 90%) Since 1981, the prevalence of type 2 diabetes has increased to twice in and the total number of cases has increased threefold in Australia (Dunstain 2002).Although type 2 diabetes is effecting all races,it was identified highly in south Asians and also worlds one-third diabetic population is from indian continent ( Jean 2008). According to the report from Centre for Disease Control and Prevention in United states of America, nearly 25.8 million people have been affected by diabetes in 2010 with 90- 95% of them being type 2 DM (CDC 2011). However, type 2 diabetes mellitus which is characterized by the deficiency and resistance of the

This particular research was driven by the demand of the regulatory guidelines that deals with reduction of risks. The cases of cardiovascular risks among patients are have been reported to increase in the recent days. The regulatory guidance require being presented for the cardiovascular outcomes that can be used in the therapies of type 2 diabetes treatment. However, the

Type II Diabetes is a growing disease that according to Ley, Ardisson Korat, Qi, Tobias, Cuilin, Lu and ... Hu (2016) approximately 415 million adults are affected by this disease world wide and in the United States in 2015, $348 million dollars was spent on treatment for diabetes. Additionally, the growing number of people who are projected to develop type II diabetes is

Furthermore, with the pharma logical treatments included in this article for the treatment of Type 2 Diabetes, many individuals will be prevented from developing CVD complications. Studies have shown the importance of patients being compliant with treatment leading to positive health outcomes. With the continued care given to these patients with Type 2 Diabetes many are able to have healthier lifestyles

Type II diabetes mellitus (DM), also referred to as non-insulin dependent diabetes, is a relative, rather than absolute, deficiency of insulin (ADA, 2004). It is global problem and has been identified as one of the “most challenging contemporary threats to public health” (Schauer et al., 2012). One is at risk for developing type II diabetes if they are overweight, over the age of 45, have a relative with type II diabetes, are sedentary, gave birth to a baby over 9 pounds, or had gestational diabetes (Center for Disease Control and Prevention [CDC], 2016).

The mainstay of type 2 diabetes medication is Metformin due to the cost, safety of the medication and limitied side effects. Metformin reduces glucose levels through two pathways; it reduces hepatic glucose production and increases the insulin tissue sensitivity. Monotherapy is normal for this medication; however, it can be utilized in combination with other medications. Metformin used in conjunction with Sodium glucose cotransporter provides a greater control over the level of glucose in the body due to the reduction of glucose production, increase in sensitivity, reduction of reabsorption of glucose and the excretion of glucose through the kidneys, basically the glucose control is through 4 different pathways making it a synergetic effect on diabetes type 2. According to Inzucchi et al.(2016), the combination of these medications helped patients reduce their overall A1c (0.5-1.0), lose weight (2kg) and a reduction in their blood

Type 2 Diabetes is a chronic condition that affects the way in which the body processes blood sugar. Type 2 Diabetes specifically is characterized by the bodies inability to process Insulin correctly, therefore leading to increased sugar and insulin levels in the bloodstream. Individuals get this disease due to poor diets filled with high carb, high sugar, a high fat processed foods and a lack of exercise. Health consequences of Type 2 Diabetes include kidney complications, eye problems, amputation, heart disease, and even death. Type 2 Diabetes is difficult to manage because Diabetics must constantly monitor blood sugar levels. According to the Mayo Clinic, doctors may recommend type 2 diabetics to check their blood glucose levels two or more times a day.

Type 2 Diabetes Mellitus (T2DM) is a chronic disease that is modifiable and preventable through diet and exercise. The incidence of T2DM is propagated by a sedentary lifestyle and excessive caloric intake. Maintenance of a desirable body weight, diet, and exercise are the mainstay therapy for T2DM (Buttaro, Trybulski, Bailey, & Sanberg-Cook, 2013).

Type 2 diabetes is the most common form of diabetes which affects 90% to 95% of the population. In the United States, approximately 1.7 million new cases of diabetes were identified in 2012 and the disease affects 29 million Americans or 9.3 percent of the population (Statistics About Diabetes, 2014). In 2012, the total financial burden of diabetes was estimated to be $245 billion which included $176 billion in direct medical costs and $69 billion in reduced productivity (American Diabetes Association, 2013). Those who have type 2 diabetes are unable to control insulin levels resulting in a condition called insulin resistance. In the first stages of the disease your body

A myriad of pharmaceutical treatment options for the treatment of type 2 diabetes (T2DM) currently exist (Inzucchi et al., 2015; American Diabetes Association, 2016). Although metformin remains the first-line pharmacologic treatment, numerous options are available when metformin alone does not achieve glycemic targets. When making treatment decisions, the American Diabetes Association (ADA, 2016) recommends that selection of additional agents should take into account the advantages and disadvantages of specific medications. They also advise consideration of patient preference, cost, side effects, impact on body weight, and risk for hypoglycemia (ADA, 2016). The intent of this paper is to explore the recently published and highly relevant research findings on the impact of empagliflozin, a sodium glucose co-transporter-2 inhibitor (SGLT2), on cardiovascular outcomes and mortality (Zinman et al., 2015).

Diabetes Mellitus (DM) type II is a major issue worldwide; as well as, a major issue here in the United States. According to the CDC (2015), in the U.S., DM is the seventh leading cause of death. Type II DM is associated to obesity as well as genetic factors and age (Whalen, Finkel, & Panavelil, 2015). There are many different treatment options for DM. This paper will discuss diabetes and its vast treatment options, including, what to monitor and potential adverse effects.