Hypertension is defined as persistent increase of blood pressure in human body. A pregnant women is considered high blood pressure when the systolic reading is greater than 140 mmHg and diastolic reading greater than 90 mmHg. High blood pressure in pregnancy is also known as ‘gestational hypertension’. Gestational hypertension could lead to development of a condition called preeclampsia. Initially, gestational hypertension is a new onset of high blood pressure after the 20th weeks of pregnancy without the presence of proteinuria and end-organ dysfunction, while in preeclampsia, which is a multi-systemic disorder will causes proteinuria and organ dysfunction1. When there is grand mal seizures happens in preeclampsia pregnant women, it is known as eclampsia1. Eclampsia is a severe end of preeclampsia which may leads to death.
The risk factors of gestational hypertension developed into preeclampsia are having past history of preeclampsia, first pregnancy, a family history of preeclampsia and some preexisting medical conditions1. Preexisting medical conditions like diabetes that related to renal or vascular disease which lead to high blood pressure and chronic kidney disease (CKD) which causes low glomerular filtration rate and subsequently lead to hypertension may develop preeclampsia. Moreover, pregnant women with twin pregnancies and maternal age may also contribute to preeclampsia3.
Other modifiable risk that lead to gestational hypertension and preeclampsia are related to
The main purpose of this article is to see what factors can contribute to the risk of induced Hypertension and Preeclampsia during a pregnancy. This article states that Preeclampsia and Hypertension can cause maternal morbidity. In this article they assess the exposure to chemicals or a physically demanding workload to the cause of a hypertensive disorder during a pregnancy.
And it is caused by great psychological stress. Hypertension affects the mother and child during pregnancy, and the medicine that doctors ask women to take for depression, while pregnant can increase the negative effects of hypertension. The hypertension can cause preeclampsia, which can lead to severe damage to you and your child. Once you have preeclampsia you must deliver your baby right than. Hypertension can also affect the child too, it can affect the newborn's heart, and lungs. Newborns coming outside of the womb actually have to be put on immediate care. The child you were carrying for 9 months will be put on immediate care because of the mediation you took while you were pregnant. While possibly curing the mother's depression, it can lead to other negative effects along the
As woman age, they will find that pregnancy can be extra hard on the body, causing health issues such as high blood pressure, with some woman developing preeclampsia. Preeclampsia, a pregnancy-induced hypertension disorder which affects both mother and fetus poses the real possibility of impacting renal function along with the development of HELLP syndrome. When a woman develops this HELLP syndrome they are a risk of hemolysis; the breakdown of red blood cells, elevated liver enzymes, and low plate count putting her a greater risk of complications that cause death (Preeclampsia Foundation, pg1). The only known way to cure this disorder is to deliver the baby and placenta, even if the baby is premature because not only can this kill the mother, but it has repercussions for the fetus as well. When it comes to the fetus, preeclampsia causes an inadequate nutrition supply because of the insufficiency of the placenta to regulate how the fetus gets its nutrients, which can lead to growth retardation and further heath compilations later in life (Lapidus MD,
sugar(American College of Obstetricians and Gynecologists Committee on Practice Bulletins--Obstetrics, 2001). Studies though, have found that women experiencing gestational diabetes are at higher risk for spontaneous preterm birth. A Northern California study of over 46,000 women screened for gestational diabetes, those who screened positive for gestational diabetes had a significantly higher risk of spontaneous preterm birth (OR:1.53, 95%CI, 1.16-2.03) (Hedderson, Ferrara, & Sacks, 2003).
Preeclampsia casuses new onset hypertension and proteinuria which is a marker of kidney damage and can also cause damage to other organs like the brain and the liver.
A popular hypothesis explaining the cause of pre-eclampsia is immune maladaptation(14).To date, the etiology of preeclampsia is not completely understood, however an increasing body of evidence indicates the involvement of the immune system in the form of faulty tolerance to the conceptus as an fundamental part of the pathogenesis(50).The immune system has been incriminated in the pathophysiology of preeclampsia with alterations in the cellular immunity and cytokines production that are work toward the maintenance of pregnancy(76). The maternal immune response against the fetus and placenta has too been proposed to have an central role in the pathogenesis of preeclampsia(185).
“Chronic hypertension is globally one of the most dangerous intercurrent diseases of pregnancy since it is associated with many serious complication for both mothers and children” (Zetterstrom, 2008). This condition presents in 1-5% of pregnancies and is higher in older, obese, and black women (Wood, 1996). It is described as having a BP higher than 140/90 mm Hg before the 20th week of gestation (Wood, 1996). Sometimes this is a continuation of pre-gestational hypertension.
The baby will have a greater risk of ischemic encephalopathy, growth retardation and the potential for premature birth (Lim, "Preeclampsia"). For the mother preeclampsia is caused by endothelial dysfunction in pregnancy (Lim, "Preeclampsia"). Preeclampsia can also be linked to future cardiovascular disease. There has been shown to be a fourfold increase in the development of hypertension and a twofold increase in ischemic heart disease (Lim, "Preeclampsia"). Although the mechanism responsible for preeclampsia is not fully understood there are several factors that have been found to contribute; maternal immunological intolerance, abnormal placental implantation, genetic, nutritional and environmental factors and cardiovascular and inflammatory changes (Lim,
To begin with, not everyone has to worry about developing preeclampsia, it is only when you are 20 weeks pregnant. There is no known cure other than having your baby. It is a very serious condition that causes your blood pressure to become high and dangerous to the expectant mother and the child. In some cases it can cause the mother to have seizers and this is called eclampsia. It causes blood not to flow to the baby and in turn the baby does not get enough oxygen, in the mother it can cause liver, kidney and brain damage.
Thank you for responding. It is clear that to prevent a complication in pregnant women with preeclampsia is to administer certain medication such magnesium sulfate, and sometimes induce labor or C-section. I am not an Obstetrician and Gynecologist nurse, but I think is hard to believe not to treat the high blood pressure on these patients who may be at risk to develop other complications like seizure or stroke. Anyway, that piece information that you have submitted was very interesting and informative at the same time. One think that I like to the science of medicine is the continuous evolution. This science is not static, but movable. That helping us to keep on continue to research so we can be up to
Gestational diabetes, glucose intolerance with onset or first recognition occurring during pregnancy, is a problem more pregnant women are facing. The exact prevalence rate of gestational diabetes mellitus is unknown but in the United States it is estimated to affect anywhere from one to 14 percent of pregnancies (Desisto, Shin, & Sharma, 2014). There are several risk factors which increase a woman’s risk for gestational diabetes. Some of these risks include: family history of diabetes mellitus, previous history of gestational diabetes, advanced maternal age, previous infant weighing 9 pounds or more at birth, glycosuria, polycystic ovary syndrome, and
pre-eclampsia could be defined as a problem that arises during pregnancy and is characterized by high blood pressure and with the contingency to damage some of the major organs, such as the kidneys. Preeclampsia is considered a serious condition that can lead to dangerous complications for both the patient and her baby. However, how exactly it is caused is not exactly known. Researchers suspect that it may involve problems with the blood vessel development in the fetus, which in turn causes a dysfunctional reaction in the mother’s blood vessels. Furthermore, the Guideline (2011) stresses that a pregnant woman should be assessed for pre-eclampsia at each consultation by measuring her blood pressure levels. For a more thorough overview this assessment
Following a healthy diet and exercise plan can reduce your high blood pressure, but massage can also help. The gentle therapy is capable of reducing stress and discomfort while also bringing down high blood pressure levels. This will not only prevent preeclampsia during your pregnancy, but it can also help reduce the risk of further complications after being diagnosed with the condition.
Few studies over the past years have compared the effects of oral nifedipine to intravenous labetalol for the control of hypertension during pregnancy. Shekhar et al., conducted a randomized, double-blinded placebo-controlled trial, to compare the effectiveness of orally administered nifedipine and intravenously administered labetalol for acute blood pressure control of hypertensive emergency in pregnancy.4 The study was conducted between October 2012 to April 2013 in the labor ward of the department of Obestrics and Gynecology of Dr. Rajendra Prasad, Government Medical College and Hospital, Tanda, Kangra, India. Women were eligible for inclusion if they were 18 to 45 years old, at 24 weeks of gestation or more, a heart rate between 60
Proteinuria is a measure utilised in the diagnosis of pre-eclampsia. However, there is debate regarding the threshold for significance. The objective of this study was to determine which proteinuria threshold is important for the clinical management of pre-eclampsia in high-risk women, with the specific aim of assessing whether women with 300-499mg/24h of proteinuria could be considered suitable for outpatient management. This was achieved by evaluating incidence of adverse maternal and perinatal outcomes against the differing thresholds of proteinuria in women with pre-eclampsia. The data was collated from a nested case-control of women who partook in a VIP Trial: Vitamins In Pre-eclampsia (2006). 947 women with singleton pregnancies were identified. They were separated into four groups, to compare women with pre-eclampsia and proteinuria (300-499mg/24h or 500mg/24h or over), to women who had no occurrence of proteinuria but had either chronic (CHT) or gestational hypertension (GH). The results of the study clearly indicate that women with proteinuria of 300-499mg/h have more severe hypertension, early deliveries and SGA infants than women managed as outpatients (CHT and GH). However it is apparent those with proteinuria above 500mg/24h are at substantially greater risk of complications than those with a level of 300-499mg/24h. It is accepted that other factors may have an adverse affect on pregnancy outcomes, but despite this the role of high