Henle: A Case Study

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The loop of Henle is a part of the kidney tubule that forms a lengthened loop within the medulla of the kidney, this is where water and salts are resorbed into the blood. The osmolarity which is the concentration of a solution that is to assert the total number of solute particles in each litre. Osmolarity within the interstitium (interstitial space within a tissue or organ) continues to rise constantly from the cortex further to the medulla and also the papilla through repeating of the single effect by counter current flow that occurs in the branches of the loop. The ascending and descending counter current exchanges of solutes through the renal medullary capillaries helps to reduce solute washout from within the medullary interstitium. Counter current system also authorises the forming of concentrated urine by the existence of ADH, this helps to increase water permeability, hyposmotic fluid travels from the thick ascending limb then enters the distal tubule. Although, it effects the urine concentration by losing majority of its water through osmotic equilibration, also it affects urine concentration due to the continual loss of NaCI through the reabsorbtive along the Distal tubule, CNT and the CCD. Counter current also authorises the forming of dilute urine which has no ADH present. Hyposmotic fluid also…show more content…
several types of Diuretics are chemicals that increase urinary output. Loop diuretics are dominant due to them inhibiting the formation of the medullary gradient this helps by acting at the ascending limb within the Henle’s loop. They exert their effect by the removal of excess fluid this further causes the Individuals kidneys to produce more urine. Because of this it results in the removal of salts and water within the individual. The Loop Diuretics comprise of four different substances such as Furosemide, Bumeranide, Torsemide, and also Ethacrynic acid (Marieb ; Hoehn;,
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