GENERIC NAME:LABETALOL - ORAL (luh-BET-uh-lol) BRAND NAMES: Normodyne, Trandate DRUG CLASS AND MECHANISM: Labetalol is a drug that is used for treating high blood pressure. Nerves from the adrenergic nervous system travel from the spinal cord to arteries where they release norepinephrine. Norepinephrine attaches to adrenergic receptors on arteries and causes the arteries to contract, narrowing the arteries, and increasing blood pressure. Labetalol blocks receptors of the adrenergic nervous system. When labetalol attaches to and blocks the receptors, arteries expand, resulting in a fall in blood pressure. GENERIC AVAILABLE: Yes PRESCRIPTION: Yes PREPARATION: Tablets: of 100, 200 and 300 mg; Injection: 5 mg/ml STORAGE: Tablets should …show more content…
If combined with adrenergic stimulating drugs used for treating asthma, ex. albuterol the adrenergic blocking effects of labetalol may counteract the effects of the stimulating drugs and reduce their effectiveness for treating asthmatic attacks. More of the adrenergic drug may be needed. SIDE EFFECTS: The most common side effects of labetalol are fatigue, dizziness, nausea, headache, diarrhea, edema (fluid accumulation), and shortness of breath. Postural hypotension (a rapid decrease in blood pressure when going from the lying or seated position to the standing position that may cause light-headedness or fainting) occurs rarely. Patients should be observed for this possible side effect within two to four hours of the first labetalol dose and after any changes in dose. Sexual dysfunction, abnormal heart rhythm, slow heart rate, liver failure, and allergic reactions may occur. GENERIC NAME: Symptoms of a Labetalol Overdose: When someone takes too much labetalol, the symptoms can vary. Some examples of labetalol overdose signs and symptoms include: Difficulty breathing, Wheezing,Extremely low blood pressure, which may cause lightheadedness, dizziness, or fainting, Severe decrease in heart rate (bradycardia),Seizures, Congestive heart failure. Treatment for an Overdose With Labetalol: If the overdose with labetalol was recent, the healthcare provider may administer certain medicines or place a tube into the stomach to "pump the stomach." However,
β receptor agonists are used in the treatment of asthma and COPD (chronic obstructive pulmonary disease) to relax the muscles in the air passages in the lungs. Salbutamol is a selective β2 adrenergic agonist, although this selectivity is relative and dose-dependent. This means that the selectivity is lost at high concentration and thus causing side-effects.
Possible side effects: “dry mouth, sedation, blurred vision (disturbance of accommodation, increased intra-ocular pressure), constipation, nausea, difficulty with micturition; cardiovascular side-effects (such as ECG changes, arrhythmias, postural hypotension, tachycardia, syncope, particularly with high doses); sweating, tremor, rashes and hypersensitivity reactions (including urticaria, photosensitivity), behavioural disturbances (particularly children), hypomania or mania, confusion or delirium (particularly elderly), headache, interference with sexual function, blood sugar changes; increased appetite and weight gain (occasionally weight loss); endocrine side-effects such as testicular enlargement, gynaecomastia, galactorrhoea; also convulsions (see also Cautions), movement disorders and dyskinesias, dysarthria, paraesthesia, taste disturbances, tinnitus, fever, agranulocytosis, leucopenia, eosinophilia, purpura, thrombocytopenia, hyponatraemia
Many people are being overdosed with this pill, but one girl named Toni Vermeer said, “Right when you take these painkillers your whole body goes numb and than you don't feel like doing anything till tomorrow night.” She overdosed while she was babysitting a six year old girl. Toni is still alive after she overdosed five times.The third time she overdosed, she flatlined
Side Effects: Frequent urge to urinate, headache (continuing), loss of appetite (continuing), mood or mental changes, muscle pain or twitching, nausea or vomiting, nervousness or restlessness, slow breathing, swelling of feet or lower legs, unpleasant taste, unusual tiredness or weakness
Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, slurred speech, tremors, a slow heartbeat, shallow breathing, feeling light-headed, fainting, seizure (black-out or
Mild withdrawal symptoms can be helped with drugs such as Tylenol, Aspiring or Ibuprofen. There are also medications that can help with diarrhea. More intense withdrawal symptoms may require other medications, such as Clonidine, which reduces symptoms including anxiety, aches, restlessness, runny nose and cramping. In the most severe cases, hospitalization will be required. It is imperative to seek the diagnosis and advice of a qualified healthcare professional to determine the severity of symptoms and what course of treatment is
While the most significant side effects, affecting some patients but not all include low blood pressure; dizziness, especially when standing up suddenly; sleepiness, lethargy, heart palpitations, constipation, weight
The dependence liability on both physical and psychological are very high. Back to the subject on overdoses, depending on a few other elements and your interactions with the drug, death from this drug, or an “overdose”, can take anywhere from 7 minutes to almost seven hours. Lack of oxygen that is caused by the opioid is the main cause of death from this. Your opioid tolerance and an unexpected increase in the drug can
The nurse should be fully aware of all potential side effects, adverse effects, and any contraindications that follow taking albuterol. The two main side effects the nurse should educate the patient on (especially the elderly), is the risk of excessive cardiac and central nervous system (CNS) stimulation, as well as nausea, headache, vomiting and coughing. Nebulizers and inhalers are associated with fewer effects than the oral route of albuterol. Muscle tremors are the most frequent effect. Contraindications should be followed excessively and the nurse should explain why the medication should highly not be taken. The most common ones are, hypersensitivity, cardiac arrhythmias, and coronary artery disease. *Caution should be taken with patients who have hypertension, hyperthyroidism and diabetes mellitus (Frandsen, 2013, p.
Asthma control varies over time due to severity and changes in the environment, for example, home, school and or work environments. There are several medications and combinations used to control asthma attacks. The first line of medication are inhaled corticosteroids used to prevent and reduce airway swelling and inhaled long-acting beta agonist used to keep the airways open and relaxed (AAFA, 2015). Examples of long-acting corticosteroids are fluticasone, budesonide, mometasone, beclomethasone, ciclesonide, flunisolide. Examples of LABA medications are salmeterol and formoterol; it is important to remind patients that these medications are not to be used in emergency situations. At times, both medications are used together in a single medication to treat asthma and prevent attacks. Some caution that patients should be aware that when using combination medication, the risk for severe asthma attacks increase (Mayo Clinic, 2015). Examples of combination medications are Advair (fluticasone and salmeterol), Symbicort (budesonide and formoterol), Dulera (mometasone and formoterol) and Breo (fluticasone and
Adverse reactions to this medication are migraine, speech disorders, rhinitis, sinusitis, hyperglycemia, elevated liver function, elevated serum creatinine level, pancytopenia, bronchitis, dyspnea, toxic epidermal necrolysis, anaphylaxis, elevated creatine kinase, generalized pain, and infection. Nursing considerations with this medication is to have the patient swallow the whole tablet and not to chew. Watch for aspiration while watching the patient take the medication. Educate the patient about the medication and inform them to notify a physician if bleeding
Demerol is a synthetic opioid that is created in a laboratory, instead of being derived from a substance in nature. The drug inhibits the section of the brain that controls pain, and it is prescribed to patients who are experiencing moderate to severe pain after surgery or an injury. In addition to alleviating pain, Demerol can produce euphoria, which can tempt people to abuse it. Some patients may struggle to stop taking Demerol, even if they have used the drug as directed. However, in addition to euphoria, Demerol can also cause confusion, delirium, and seizures.
The frequency spectrum in metoprolol treated animals demonstrated a reduction in mean frequencies from 1 to 3min (electrical phase) and from 3 to 7min (circulatory phase). Labetalol produced an even greater reduction in frequencies in these intervals. The decline in AMSA was similar in all three groups over the first 3min. From 3 to 7min the metoprolol group was significantly lower than the control group (p<0.001 vs compared to control and metoprolol groups). ROSC was noted in 2/10 in the control group, 7/8 in metoprolol group and 2/7 in the labetalol group. The frequentist analysis of ROSC showed a relative risk (RR) of ROSC of 4.4 when comparing control to metoprolol animals and 1.4 comparing control to labetalol
Package A contained either intravenous labetalol vials (total 60mL as labetalol 5 mg/mL) and 5 placebo tablets or IV saline placebo (60mL as 0.9%) and five 10-mg nifedipine tablets. Package B, which contained the opposite regimen of A, was utilized as a crossover treatment if the target blood pressure was not achieved after 5 cycles of regimen A.
Mannitol can be truly useful in the clinical setting as a diagnostic agent, osmotic diuretic and urinary irrigant. Mannitol’s chemical class is hexahydroxy alcohol and it is a pregnancy category B drug. Mannitol is a six-carbon sugar and is known by the generic name of mannitol or Osmitrol, which is the most common brand name. Mannitol is usually available in 5%, 10%, 15%, 20%, and 25% injection form. Mannitol is considered a diuretic which promotes urine production. It is also helpful in preventing the kidney from shutting down. It increases osmotic pressure of the glomerular filtrate, inhibiting reabsorption of water and electrolytes and creates an osmotic gradient in the glomerular filtrate and blood (Lippincott Williams &