Royal jelly treatments caused significant reductions in serum LDL-C, VLDL-C, TG, TC levels and induced significant elevations in HDL-C level. These results may be due to that RJ decreased gene expression of squalenee poxidase enzyme (SQLE), "key enzyme in cholesterol biosynthesis" and also cause decrease in sterol regulatory element binding protein (SREB)-1, which may be a transcriptional factor of SQLE. On another hand, RJ increased gene expression of low-density lipoprotein receptor (LDLR) (Kamakura et al., 2006) or may be a result of lowering very low-density lipoprotein (VLDL) levels due to RJ strongest hydroxyl radical scavenging quality (Guo et al., 2008). Atherogenic index is a predictor of the development of …show more content…
Treatment with RJ induced significant decrease in the level of blood glucose and the treatment with RJ before or after cholesterol caused a significant decrease in the level of blood glucose. This may be related to the antioxidant properties of the RJ which improves insulin levels. This result agreed with Khoshpey et al. (2016) who suggest that RJ intake may have desirable effects on blood glucose and decrease blood glucose levels in people with type 2 diabetes. But, this result is not agreed with Sarita et al. (2011) who investigate the effects of different doses of royal jelly supplementation on blood glucose level in swimmers and conclude that RJ supplementation at different doses did not affect glucose levels Administration of cholesterol to rats caused significant decrease in serum total protein, albumin and globulin levels. These results are is in line with results of Olorunnisola et al. (2012) who showed that there was a significant decrease in levels of total protein, albumin and albumin/globulin ratio in rats which fed on high cholesterol diet when compared to animals with normal diet. This may be due to hypercholesterolemia caused an impairment of liver function and leads to decrease in the capacity of hepatic parenchyma to synthesis albumin which lead to the decrease of serum total albumin and globulin levels (Ghorab, 2014). Treatment with RJ induces a
In the field of occupational therapy, activities of daily living, more commonly referred to as ADL’s, are a major component for assessing a client’s issues and developing a treatment plan. In the study “ADL Differences in Individuals with Unilateral Hemispheric Strokes”, authors Patricia Rexroth, Anne G. Fisher, Brenda K. Merrit and Jeff Gliner try to gain a better understanding of ADL patterns in unilateral hemispheric stroke victims. Their purpose in designing this study was due to the inconsistent research findings from other studies in the relationship between age, gender and ADL ability in people with left cerebrovascular accident [(L) CVA] and right cerebrovascular accident [(R) CVA]. The authors’ hypothesis as stated from the article
In a study conducted in 1985 observing primates, it was determined that the major effect of dietary cholesterol is its LDL raising effects. High intakes of cholesterol increase the number of circulating LDL’s and it can also change its size and composition. [12] It was during this time period that the mechanisms by which SFA are thought to increase blood cholesterol concentrations came about. One mechanism for the increase in LDL cholesterol levels is the suppression of LDL receptor activity. Studies in tissue cultures have shown that increasing the cholesterol content of a cell will down-regulate synthesis of LDL receptors. [13] This will lead to an increase in concentration of blood cholesterol. Another cause for an increase in blood cholesterol concentration through intake of dietary SFA is the composition of the newly secreted lipoproteins. With a high saturated fat intake, the LDL’s become rich in cholesterol esters, leaving the triglycerides in the blood. [14] The use of non-human primates in
Our body naturally produces cholesterol through the liver, we can also obtain cholesterol from consumed products. We need small amounts of cholesterol to produce hormones, bile, and vitamin D. Cholesterol doesn’t dissolve in the bloodstream once it is inside the body. It needs to be carried by two types of lipoproteins called low density lipoproteins(LDL) and high density lipoproteins(HDL). The more cholesterol we consume, the more LDL and HDL we produce. HDL is
This 54 year ld AAM. Patient has a history o fDM, HTN, and hyperlipidemia. Patient's current medications are Glipizide 10 mg BID, ASA 81 mg QD, Triamtereine /HCTZ 75/50 mg, Pravastatin 40 mg QHS, and lorsatan 300 mg QD. Patient states he is taking all mthe medications as prescribed, and he thought he was doing fine. Patient states no one in the Federal Prison System had checked his A1C in several years. The patient's A1C today is greather than 14 %. Patient denies buller vision, headache, chest pain, SOB, N/V/D, or fever. The patient denies decreased sensation of his feet, increased thirst or urination. Patient denies any depressive moods. The patient is here with his wife and had a long disussion with the plan of care for his DM, HTN, and
The second iteration of the LTBI Project was situated in a Southeastern United States school in which 71% of the students are categorized economically disadvantaged. This racially diverse student population and their teachers were navigating their very first year of the Common Core State Standards for Mathematics and English-Language Arts during the yearlong professional development. The professional development format consisted of a 30 hour summer institute that spanned 4 days, monthly meetings during the school year that totaled 24 hours, and 1 full day meeting at the end of the school year. Professional development activities aimed to engage participants in Professional Learning Tasks (PLTs) that provided opportunities to attend to pedagogical
Four studies focused on determining a link between CVD risk, LDL particle size and number (LDL-P), and total cholesterol content within the body. For the first study completed by Toth et al11, CVD incidence was compared to LDL-P thresholds by analyzing the frequency of CVD events during a six-month period. The researchers considered the baseline LDL measurement as the day in which the most recent LDL-P value was gathered prior to a CVD event, referring to it as the index date, and the researchers assessed outcomes throughout the entire study period. CVD events were verified utilizing the ICD-9 diagnosis codes and the study ended if the patient lost their health plan eligibility, data was no longer available, or the patient died at
Common mixes contained in raspberry plants that are equipped for managing digestion system the same as capsaicin and synephrine, and are synthetically like them, are known as raspberry ketone. The reason that raspberries notice so charming is likewise in view of the ketones, and they are additionally utilized as a part of handled nourishment as an enhancing fixing. The compound is utilized as a part of beauty care products to give them a pleasant sweet-smelling aroma. After various studies with rats, it has been demonstrated that these ketones are fat eliminators, and this is the reason that raspberry ketone supplements are by and large generally promoted as a powerful weight reduction arrangement.
Patients who were diagnosed with DLBCL as the only primary cancer using surveillance epidemiology and end results (SEER) data base from 1983 till 2017 as the data of gastric cancer and Ann Arbor staging information were not presented at that time.
We sum up that the IPB-1+CO diet could induce similar characteristic in body measurement and plasma lipid profiles with western atherogenic diet and suggested that responsiveness could be a good sign to choose the individual monkeys as an atherosclerosis model with any atherogenic diet, included IPB-1+CO. If there was no increase of TPC at the first 3 months of feeding, the monkeys might not produce a hypercholesterolemia, although for long term feeding, and might not form the plaques in the arteries.
due to their estrogenic interest, isoflavones may be the bioactive aspect attributed to soy protein. excessive isoflavone, combined with excessive soy protein intake leads to significantly reduced serum overall and LDL cholesterol as compared to low isoflavone intake. a few authors suggested that ingested purified isoflavones exert lipid-decreasing outcomes (Ae Park et al. 2006; Kojima et al. 2002; Sosić-Jurjević et al., 2007). however, others confirmed minimum or no outcomes of remoted isoflavones on blood lipid tiers (Greaves et al., 1999; Molsiri et al., 2004).
This study showed that, administration of E. jambolana significantly recovered the hepatic TBARS level in untreated diabetic rats. These results are underlined by the
Raspberry ketone (4-(4-hydroxyphenyl) butan-2-one; RK) is a major aromatic compound of red raspberry (Rubus idaeus). The structure of RK is similar to the structures of capsaicin and synephrine, compounds known to exert anti-obese actions and alter the lipid metabolism. The present study was performed to clarify whether RK helps prevent obesity and activate lipid metabolism in rodents. To test the effect on obesity, our group designed the following in vivo experiments: 1) mice were fed a high-fat diet including 0.5, 1, or 2% of RK for 10 weeks; 2) mice were given a high-fat diet for 6 weeks and subsequently fed the same high-fat diet containing1% RK for the next 5 weeks. RK prevented the high-fat-diet-induced elevations in body weight and the
LDC's usually involve these characteristics poverty, conflict, illiterate and poorly educated people, political injustice, and severe inequality. Least developed or developing countries face these challenges nation building, state building, participation, and distribution. Nation building is forming an identity for the country, that is different than others. State building is creating a political institution that is capable of controlling and allocating resources in the country. The next challenge many face is the participation shown by the people, to have a functioning government people must be involved. The last challenge is distribution of wealth to help prevent inequality. I agree with what Magstadt is saying in the chapter. I also think
Both alcohol consumption and metabolic syndrome are risk factors for development of fatty liver diseases with similar pathology which ultimately can result in development of liver cancer.3, 4, 24-273, 4, 23-26 Using a two-stage mouse model in which tumor initiation by DEN was followed by a 35% high fat diet, we have previously reported increased tumor incidence, suggestive of a diet-related promotional effect.11 Consistent with these findings, in the current study, we observed increased adenoma incidence and tumor multiplicity in the HF/CAS group relative to chow controls. More importantly, substituting SPI for casein in the diet produced a marked reduction in hepatic lipid accumulation, inflammation and cell proliferation, resulting in lower tumor incidence and multiplicity.
Virtually clinical studies provided the evidence that Vaccinium berries ameliorate dyslipidemia. However, except Habanova and colleagues found after 42 days bilberry(froze-stored) intake, there was a significant decrease of triacylglycerol(TG) (P80%), which suggest that heterogeneity plays an important role on variability(38,39). Therefore, it is worth to mention that since different dose, form of Vaccinium berries, duration, characteristics of participants, uncharacterized bioactive compounds, and study designs among these studies, rigorous evidence is needed.