Mucoepidermoid Carcinoma Research Paper

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Malignancies of the nasal cavity and paranasal sinuses constitute fewer than 1% of all malignancies and 3% of upper aerodigestive tract malignancies. [1] The majority of these tumors are in the maxillary sinus, and squamous cell carcinoma is the commonest histological type [2]. Mucoepidermoid carcinoma (MEC) arising from mucous glands of maxillary sinus are extremely rare and accounts for 13% of all malignancies, [1] Kraus et al, in his study of 49 patients with non squamous tumours of maxillary sinus reported sarcomas, adenoid cystic carcinomas, lymphoma and adenocarcinoma accounting for most of their cases. [3] Sinonasal malignancies occur twice as often in males as in females, and are most often diagnosed in patients 50 to 70 years of age. [4] …show more content…

[5] This type of carcinomas once been regarded as benign lesions , called mucoepidermoid tumour later, WHO(1990) recommended as mucoepidermoid carcinoma Stewart et al (1945) was the first to describe as MEC is a separate pathological entity. [6] Peak age of occurrence of mec is older age with mean of 44.5 years. [7] MEC tumours occur in major salivary glands [53%] ; parotid gland [45%] followed by the minor salivary glands of the palate [25%]. [5] Histologically, MEC is classified into three types of malignancy-low, intermediate, and high grade using five histopathological features namely intracystic component, neural invasion, necrosis, mitosis and anaplasia. [5] The main therapeutic method in the treatment of MEC, like in most types of salivary gland malignancies, is surgical resection and post-operative radiotherapy seem to be efficient. [7] As MEC is a rare carcinoma among all, no risk factors are known, long term outcome of the data are difficult to diagnose. We report a rare case of mucoepidermoid carcinoma of maxillary sinus in a 16-year-old female with clear cell

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