Mutations in Genomes

Decent Essays

Mutations can occur in any genome, some are good and some are bad. Addition and deletions of certain parts of a gene cause a wide range of disorders in certain organisms. These mutations are called copy number variations (CNVs). For purposes already stated, when one looks into how
CNVs create neurological disorders, one must understand that any change in a genome will produce an effect. It can positively affect the organism or negatively affect it, and there are certain genomes that if changed will be the source of proteins that will help in brain function.
Because CNVs are present, abnormal or completely different proteins can cause a plethora of results, causing the brain of that organism to be abnormal in some way, leading to neurological disorders. A well-known example of this is Autism.
Autism is a disease that produces abnormal brain function in humans. It specifically affects mRNAs, which are the code structures that give instructions for cells to make certain proteins, and it has not had significant research until fairly recently. There are also studies of gene redundancy and how organisms with similar genetic codes differ, such as twins. These findings are significant, because the possibility of having twins with one twin being autistic is quite possible, and it wouldn’t make a difference if they weren’t twins. Another example of neurological disorder is Down syndrome.
Scientific American brings a unique perspective to the subject of multiple copies of many genes

Get Access
Get Access