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PCOS Syndrome

Decent Essays
In 1935, Stein and Leventhal designated PCOS as a syndrome due to its association with varying degrees of hirsutism, chronic anovulation, bilateral ovarian enlargement, and obesity. While with the advent of hormonal assays, the diagnostic criteria have been for some time based on the increase in serum androgen and luteinizing hormone (LH) levels, with an increased LH/follicle-stimulating hormone (FSH) ratio. In 1990, during an expert conference sponsored in part by the National Institute of Child Health and Human Disease (NICHD) of the NIH, the participants agreed that the major diagnostic criteria for PCOS should include (in the order of importance) i) hyperandrogenism (HA) and/or hyperandrogenemia, ii) menstrual dysfunction, and iii) exclusion
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