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Psychopathology: Comorbidity Of Mental Disor

Decent Essays

Most psychopathology research to date is guided by the conceptualization of psychopathology adopted by the current nosological systems, the Diagnostic and Statistical Manual of Mental Disorders (DSM) and the International Classification of Diseases (ICD). These nosological systems conceptualize mental disorders as discrete categorical entities. In these diagnostic manuals, several categories of mental disorder are listed, the membership in which depends on whether an individual meets a number of suggested criteria (APA, 2013; WHO, 2016). Thus, an individual is either a member or nonmember of these categories (Krueger & Markon, 2006a). The DSM-5 acknowledged the limitations of this approach and provided several assumptions that needed to be …show more content…

The associated liabilities model that they proposed, in which comorbidity arises as a result of the correlation of the risk factors of these disorders, was the starting point for the hierarchical dimensional approach in psychopathology. Krueger (1999), adopting a dimensional approach, performed confirmatory factor analyses in patterns of comorbidity among ten common mental disorders and found that a two-factor model had the best fit. The first factor reflected externalizing difficulties and was composed of alcohol dependence, drug dependence, and antisocial personality disorder. The second factor was an internalizing factor composed of internalizing problems. This factor bifurcated to two subdimensions including fear (social phobia, simple phobia, agoraphobia, panic disorder) and anxious-misery (major depression, dysthymia, generalized anxiety disorder). Kendler and colleagues (2003) confirmed the same factors and demonstrated that the comorbidity in internalizing and externalizing disorders, and within anxious-misery and fear disorders are driven primarily by shared genetic …show more content…

Krueger and Markon’s (2006b) meta-analysis of multivariate studies supported the two-factor liability model for internalizing and externalizing dysfunctions with internalizing bifurcating in fear and distress liabilities. These liabilities were conceived as indirectly observed or latent natural tendencies to develop directly observed or manifest disorders, and evidence for their continuity was provided (Krueger & Markon, 2006b). This model allows for the transcendence of the distinction between normal and abnormal phenomena and views psychopathology as variations in normal-range personality traits (Krueger et al., 2007). The externalizing liability is thought to underlie disorders, such as conduct disorder, antisocial personality disorder, and addictive disorders, linked to disinhibitory traits (Krueger & Markon, 2006b). The distress liability of the internalizing spectrum is thought to underlie major depression, dysthymia, and generalized anxiety disorder, whereas the fear liability is thought to underlie panic disorder and the phobic disorders (Krueger & Markon,

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