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Chapter 6 Explain what free energy is and how it can be used to predict the energetic outcome of chemical reactions.Free energy is defined as the energy available to do work in any system. The free energy is denoted by the symbol G. G = H – TS* H: the energy contained in a molecule’s chemical bonds, called enthalpy.* TS: the energy term related to the degree of disorder in the system. T is the absolute temperature (K), and S is the entropy.We can use the change in free energy to predict whether a chemical reaction is spontaneous or not:- G positive: the products contain more free energy than the reactants. The bond energy (H) is higher, or the disorder (S) is lower. Therefore, the reaction is NOT spontaneous because it requires the …show more content…

By bring two substrates together in the correct orientation or by stressing particular chemical bonds of a substrate, an enzyme lowers the activation energy required for new bonds to form; quickly.The enzyme is not changed or consumed in the reaction; it is reusable.- Active sites: the enzyme’s pockets. Substrates bind to the active sites, forming enzyme-substrate complex. Substrate fits amino acid groups are very close to the substrate’s bonds side groups interact chemically with substrate, stressing or distorting a particular bond and lowering the activation energy required to break it substrate bonds broken new bonds formed products leave.- Multienzyme complexes: Noncovalently bonded enzyme assemblies that are good because:1- the product of one reaction can be delivered to the next enzyme without releasing it to go.2- the substrate does not leave the complex so unwanted reactions are prevented.3- all reactions are controlled as a unit.- Ribozymes: They have folded structures and catalyze reactions on themselves (intramolecular catalysis). Others catalyze other molecules (intermolecular catalysis). Plays a key role in ribosome function; the ribosome itself is a ribozyme. List the factors that affect enzyme activity.-Temperature: The rate of an enzyme-catalyzed reaction increases with temperature, because it increases random

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