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Symptoms And Symptoms Of Dengue Fever

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Dengue Fever is a well-known arbovirus infection persistently affecting the tropical and subtropical areas sharing similar characteristics of overcrowding, clammy warm climate, poor economic and moving toward industrialization. (1) The incidence of dengue fever is escalating each year mostly in Southeast Asia, America and the Pacific’s adding to the world’s burden of the disease (1,2) Dengue virus is a member of flavivirus genus family that includes also West Nile virus, yellow fever, zika and Japanese encephalitis virus (1). Four serotypes of dengue virus identified DENV 1-4 transmitted by the Aedes aegypti and Ades albopictus mosquitoes (3) Clinical diagnosis of dengue fever remains a challenge and requires high index of suspicion. This could be attributed to the non-specific signs and symptoms in acute phase which mimic many other febrile illnesses (1). It has a spectrum of symptoms ranging from mild self-limiting symptoms (fever, headache, retro-orbital pain, weakness, myalgia, arthralgia, nausea, vomiting, rash and sore throat) to severe life threatening; dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSH) (3,4). The disease has an incubation period of 2-7 days and has been classified into primary and secondary infection, depending on whether there is no previous exposure to dengue virus or flavivirus related vaccine (primary) or there is past exposure (secondary) (1,4).
While no definitive treatment for dengue fever and no vaccine available, early detection

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