Treatment and Nutrition for Diabetes “In 2012, 29.1 million Americans, or 9.3% of the population, had diabetes; approximately 1.25 million American children and adults have type one diabetes (Statistics About Diabetes ).” Diabetes is a group of metabolic diseases in which a person’s body either doesn’t produce an adequate amount of insulin, their body doesn’t understand how to respond properly to insulin, or both. In a diabetic’s body, the lack of insulin allows sugar to remain in the bloodstream which then denies cells the right amount of sugar needed for fuel. There are three common forms of diabetes: type one, type two, or gestational. “Type one diabetes may account for five to ten percent of all diagnosed cases of diabetes; type two diabetes may account for ninety to ninety-five of all diagnosed cases of diabetes; gestational occurs in two to five percent of all pregnancies but usually disappears when the pregnancy is over (William Hessel Library Database Remot...).” Diabetes is rising at an alarming rate, and while researchers don’t know what exactly causes type one, it’s believed to be linked to three things: genetics, autoimmunity, and virus or chemical. “Over half of the people that get type one diabetes have inherited the gene cell type DR3/DR4 (Peter Chase ).” But the immune system has also been known to attack the beta cells in the pancreas that are responsible for creating insulin. In the process, the immune system destroys the cells. Antibodies that include
Type 1 diabetes is also called insulin-dependent because the pancreas produce little to no insulin due to the destruction of beta cell in pancreas(Bardsley et al, 2004). Therefore, the insulin have to be injected manually for body to function normally. (Seewaldt et.al, 2000) states that in type 1 diabetes, the beta cell located in the islets of Langerhans have antigen that cause the immune system to produce antibodies and kill the insulin producing cells. The autoimmune response is thought to be caused by the autoreactive CD4 and CD8 effector cells that recognise islet self-antigens, as an outcome there is greater than 90% destruction on insulin producing cell BACH (1994). Similarly, (Nakayama et al,2005) and (Kent et al, 2005) supports that insulin in itself is a
Diabetes is a growing concern and health challenge for the American people (b). Diabetes is a condition in which the body cannot react to insulin appropriately or either cannot produce insulin efficiently (w). “Without a properly functioning insulin signaling system, blood glucose levels become elevated and other metabolic abnormalities occur, leading to the development of serious, disabling complications” (w). There are numerous forms of diabetes amongst the nation, however, there are three main forms of diabetes. Most people have heard of type one diabetes, type two diabetes, and gestational diabetes because they are common. Type two diabetes deals with a resistance to insulin, while
Diabetes type 1 develops when the immune system attacks the only cells that create insulin, the pancreatic beta cells. Due to the cells being destroyed, the person with diabetes type 1 has to be
When I found out that T1D had no cure, I began researching myself. I stumbled upon one of the many trials doctors have been running in an attempt to cure diabetes. This one, however, fascinated me. This trial included beta cells. Beta cells are cells in the pancreas whose main function is to produce and secrete insulin. In people with Type One Diabetes, however, these cells are recognized as enemies and destroyed by the immune system. This bodily attack causes the low number of beta cells within a type one diabetic’s pancreas.
Diabetes Type 1 is a severe chronic disease, which arises from the lack of insulin caused by the destruction of insulin producing beta cells of the pancreas. It is an autoimmune disease that attacks and destroys beta cells. In a healthy body, the immune system works as a guard, protecting our body from various foreign substances, such as viruses and bacteria, although in case of type 1 diabetes immune system destroys body’s own cells. (CITE)
Type 1 Diabetes Mellitus is a disease that occurs when insulin-producing beta cells of the pancreas are damaged or are being destroyed (Mahan, Escott-Stump & Raymond, 2012). The gradual destruction of the beta cells of the pancreas usually leads to complete insulin deficiency, which ultimately manifests itself in the following symptoms at clinical onset: “high blood glucose (hyperglycemia), frequent urination (polyuria), excessive thirst (polydipsia), and a significant amount of weight loss, dehydration, electrolyte disturbances and ketoacidosis”, requiring dependency of exogenous insulin in order to promote optimal glycemic control in order to prevent further more severe complications; such as, ketoacidosis, microvascular diseases, macrovascular diseases, neuropathy, or worse – Death (Mahan et al., 2012). Type 1 Diabetes Mellitus can result from two existing forms: 1. Immune-mediated diabetes Mellitus, which is characterized by autoimmune destruction of the beta cells of the pancreas and an idiopathic (unknown cause) commonly seen in ethnic groups of African or Asian descent (Mahan et al., 2012). Of all diagnosed diabetes cases, prevalence of Type 1 Diabetes Mellitus cases account for 5%-10%, and although onset may present itself at any age, 70% of cases are diagnosed in young adults (younger than age 30), with a peak in occurring incidences seen mostly in children and adolescents (Mahan et al., 2012). “In the United States, approximately 1 in every 400
What is Diabetes Mellitus? Diabetes Mellitus is common metabolic disease affecting 29 million Americans (CDC 2014), in which the pancreas produces little or no insulin resulting in an elevation of blood glucose. Diabetes Mellitus is present in three forms; type 1, type 2, and gestational Diabetes Mellitus. Diabetes Mellitus Type 1 is usually diagnosed in children and young adults with only 5% of Diabetes patients having this form (American Diabetes Association 2015). With this type of Diabetes Mellitus the body does not produce insulin to break down sugar and starches in the blood. Patients with Diabetes Mellitus Type 1 often require a long term treatment of insulin injections, exercise and diet. Diabetes Mellitus Type 2 is the most common form of Diabetes Mellitus in which the body produces too little insulin. At first the body will produce too much insulin due to insulin resistances, but over time the pancreas will not be able to keep and will begin producing too little. In most cases this type can also be controlled with exercise and a strict diet. Gestational Diabetes Mellitus is the diagnosis of Diabetes Mellitus, most often occurring around the twenty-fourth week of pregnancy. This form of Diabetes Mellitus is usually temporary and insulin production returns to normal after child birth.
There is Type 1, Type 2, and gestational diabetes. Type 1 diabetes is caused by autoimmune disease. Basically, the body’s immune system misidentifies cells as “outside invaders” and tries to kill them, even though the certain cell is harmless. In this case, those with Type 1 are unable to produce insulin at all because their immune system destroys the cells that make it. This diabetic condition is commonly described as juvenile diabetes due to the age group it is commonly found in. It is common among Northern European descent Unlike Type 1, the pancreas’s ability to produce insulin is not affected in Type 2 patients. But their body becomes resistant to insulin. To be insulin resistant means that the cells do not absorb glucose, hindering the body’s ability to use insulin effectively. Eventually, the amount of insulin produced becomes insufficient, resulting in Type 2 patients to have low levels of insulin. The third type of diabetes is uncommon and is different from Type 1 and Type 2. Known as gestational diabetes, this only occurs in pregnant women, and ends as soon as the pregnancy ends. Researchers suggest that the cause may be the fetus, which is “looking for Mommy to stock the buffet table with sugary glucose”.
Type 1 diabetes is an autoimmune disease that begins when the pancreas quits making insulin. Insulin plays a key role by letting glucose enter the body’s cells, and then uses it for energy. When the body doesn’t get the
While researchers know that type 1 diabetes is a form of an autoimmune disease in which our body’s own immune system attacks the islet of Langerhans where the beta cells are found in the pancreas, the exact reason why they do so is still being researched. However, researchers have assumed that the most widely accepted cause of the autoimmune diabetes is a T-cell mediated autoimmune disease, and that the antibodies attack the beta cells of the pancreases (Kawasaki1, 2014). The reason for this autoimmune attack can also be correlated with what is known as the HLA system, which stands for Human Leucocyte Antigen complex. This complex is what enables the body to be able to
Type 1 Diabetes Mellitus (T1DM) is a disease caused by the inability of the body to produce insulin. As a result of the human defenses against autoimmune disorders, insulin-producing cells in the body are identified as foreign and therefore targeted by immune cells for destruction. Insulin is a hormone produced by the pancreas, which is responsible for regulating blood glucose levels through the regulation of glucose uptake from blood into storage cells. High levels of blood
In type 1 diabetes, the immune system of a person’s body attacks and damages the cells that produce insulin.
Type 1 Diabetes Mellitus is a disease that occurs when insulin-producing beta cells of the pancreas are damaged or are being destroyed (Mahan, Escott-Stump & Raymond, 2012). The gradual destruction of the beta cells of the pancreas usually leads to complete insulin deficiency, which ultimately manifests itself in the following symptoms at clinical onset: “high blood glucose (hyperglycemia), frequent urination (polyuria), excessive thirst (polydipsia), and a significant amount of weight loss, dehydration, electrolyte disturbances and ketoacidosis”, requiring dependency of exogenous insulin in order to promote optimal glycemic control in order to prevent further more severe complications; such as, ketoacidosis, microvascular diseases, macrovascular diseases, neuropathy, or worse – Death (Mahan et al., 2012). Type 1 Diabetes Mellitus can result from two existing forms: 1. Immune-mediated diabetes Mellitus, which is characterized by autoimmune destruction of the beta cells of the pancreas and an idiopathic (unknown cause) commonly seen in ethnic groups of African or Asian descent (Mahan et al., 2012). Of all diagnosed diabetes cases, prevalence of Type 1 Diabetes Mellitus accounts for 5%-10%, and although onset may present itself at any age, 70% of cases are diagnosed in young adults (younger than age 30), with a peak in occurring incidences seen mostly in children and adolescents (Mahan et al., 2012). “In the United States approximately 1 in every 400 to 500
Type one diabetes is a severe disease. It happens when the body’s immune system attacks and kills the insulin-producing cells in the pancreas, called beta cells ( Jdrf ). With type one diabetes one is completely dependent on insulin injections and has an insulin pump to constantly give the body doses of insulin throughout the day. In 2008—2009, the annual incidence of diagnosed diabetes in youth was estimated at 18,436 with type one diabetes, and 5,089 with type two diabetes (ADA). The statistics show type one is found more often than type two is. Insulin plays a huge role in one’s everyday life.. With diabetes there is damage to the cells that help the glucose move to the cells of the body. Which results in glucose
Diabetes is a problem with the human body which causes blood glucose levels to rise higher than normal. This is also called hyperglycemia. There are three types of diabetes, type 1, type 2 and Gestational diabetes. Type 1 diabetes is usually diagnosed in children and young adults, and was previously known as juvenile diabetes. 5 to 10 out of 100 people who have type 1 diabetes. Type 2 diabetes are formerly called adult onset or non-insulin dependent diabetes, it can develop at any age as well. It most commonly becomes apparent during adulthood. Type 2 diabetes accounts for the vast majority of people who have diabetes that is 90 to 95 out of 100 people. In type 2 diabetes, the body isn 't able to use insulin the right way. Once type 2 diabetes becomes worse, the pancreas may make less and less insulin. This is called insulin deficiency. Gestational diabetes is a common complication of pregnancy. Diabetes is currently among the top five causes of death in most high-income countries and resulted in 4.6 million deaths globally in 2011 (Garcı´a-Pe´rez LE, Alvarez M, Dilla T, Gil-Guille´n V, 2013). Approximately 552 million persons with diabetes in 2030 (SEC, 2014)