Tuberculosis Is The Most Common Opportunistic Infection And Cause Of Death Among People Living With Human Immunodeficiency Virus

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Tuberculosis (TB) is the most common opportunistic infection and cause of death among people living with Human immunodeficiency virus (HIV) (Olaniran, Hassan-Olajokun, Oyovwevotu & Agunlejika, 2011). HIV-positive patients have about a 20-37 folds higher chance of developing Tuberculosis than their HIV-negative counterparts (Kamath, Sharma, Pattanshetty, Hegde & Chandrasekaran, 2013) The interaction between these two diseases has synergistic effect leading to excessive burden on the patient, their support network and the society at large. According to Siika,Yiannoutsos, Wools-Kaloustian, Musick, Mwangi, Diero & Carter (2013), TB accounts for about 26% of all HIV/AIDS-related deaths with more than 90% of the deaths occurring in developing countries, mostly in Sub-Saharan Africa. HIV-TB co-infected patients have been shown to have worse treatment outcomes (high mortality, Defaulter, Failure, etc.) than when treating TB alone. WHO has worked to provide a national programs and stake holders with guidelines on how to implement and scale up collaborative TB/HIV management activities that can be tailored to each adapting country’s unique context. The purpose of the paper is to critically appraise this generic guideline using the Appraisal of Guidelines for Research and Evaluation (AGREE) Instrument particularly evaluating the process and outcome measures related to this guideline. Reasons for the Chosen Guideline as a “Good Fit” This clinical guideline was developed as a

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