Tuberculosis Is The Most Common Opportunistic Infection And Cause Of Death Among People Living With Human Immunodeficiency Virus

Tuberculosis has long been a disease that the human culture has been dealing with which entails significant morbidity and mortality worldwide. With dealing with such a horrific disease over the years, discoveries and evolution on the appropriate ways to contain, diagnose, and challengingly treat the disease has changed. One of the most concerning complications of this worldwide public health issue is the ability for it to quickly spread in high populated areas while becoming ever more resistant to forms of treatment not available in all locations around the world. This is a serious public

TB is still proven to be a top killer around the world, and with more cases of drug resistant TB being reported daily, the cost of treating and preventing this disease will continue to be on the rise.

Tuberculosis is a deadly disease that is now affecting our world and the people living in it in a horrible way. Due to many factors such as poverty, HIV/AIDS, and lack of health care, many third world and developing countries have been left very vulnerable to tuberculosis. It is affecting a large part of these countries and is leading them deeper into poverty and sickness. The effort to help these countries against tuberculosis has only been slightly effective against this widespread and destructive disease.

Tuberculosis is a disease of an infectious nature caused by a bacterium known as mycobacterium tuberculosis. The disease spreads through the air. People with the disease can spread it to susceptible people through coughing, sneezing, talking or spitting. It mainly affects the lungs and other parts such as the lymph nodes and kidneys can also be affected. The symptoms for TB are fatigue, coughing, night sweats, weight loss and fever. One third of the population of the world is affected with mycobacterium tuberculosis. The rate of infection is estimated to be one person per second. About 14 million people in the world are infected with active tuberculosis. Drug resistant TB has been recorded to be a serious public health hazard in many countries. Resistant strains have developed making it difficult to treat the disease. TB has caused millions of death mainly in people living with HIV/AIDS ADDIN EN.CITE Ginsberg19981447(Ginsberg, 1998)1447144717Ginsberg, Ann M.The Tuberculosis Epidemic: Scientific Challenges and OpportunitiesPublic Health Reports (1974-)Public Health Reports (1974-)128-13611321998Association of Schools of Public Health00333549http://www.jstor.org/stable/4598234( HYPERLINK l "_ENREF_3" o "Ginsberg, 1998 #1447" Ginsberg, 1998). The World Health Organization came up with the DOTS (Directly Observed, Therapy, Short course) strategy. The approach involves diagnosing cases and treating patients with drugs for about 6-8

Tuberculosis, the white plague as used to be called once upon a time is still one of the deadliest bacterial killers affecting almost all parts, all corners of the globe. Though successful anti-tubercular antibiotic regimens and effective vaccine are available for decades and being used in the battle against Koch’s bacillus, Mycobacterium tuberculosis, the causative agent of this chronic multi organ granulomatous disease, our strand in the battle continuously seems to be in the losing side. Moreover the increasing prevalence of HIV-AIDS and diabetes mellitus is being proved to be providing predisposition to tuberculosis. As witnessed by the WHO, which has estimated that, in the year 2012, 8.6 million people have developed tuberculosis and 1.3 million have died of the disease including 320000 deaths of HIV-TB co-infected people (Global tuberculosis report 2013. World Health Organization; 2013). Long term antibiotic therapy and that too associated with several side effects and discomforts have diminished patient compliance with the anti-tubercular chemotherapy. This fact in turn has raised the new deadlier MDR-TB and XDR-TB strains. The whole scenario is a matter of panic and questioning the effectiveness of anti-tubercular antibiotics, immunologic efficacy of century old BCG vaccine and all other medical advents.

The AGREE II instrument which stands for the "Appraisal of Guidelines for Research & Evaluation” was developed to analyse the variability, methodology and quality of guidelines, as well as what information and how information is reported within the guidelines. (Brouwers et al., 2010).

It is very important to know that TB can be treated and cured by taking the required medication that could last for around 6 to 9 months depending in the dosages. It is very important as recommended for all types of medication to make sure it is taking properly and is finished to avoid getting sick all over again. Selected studies were evaluated for their objective(s), design, geographical and institutional setting, and generalizability. Studies reporting health outcomes were categorized as primarily addressing efficacy or effectiveness of the intervention (Cobbelens, 2012). Tuberculosis can be cured and the social elements have always been an important issue on who will get the disease and who will be able to receive help to become cured. This disease will remain a worldwide issue for many individuals. Medication is continuing to treat as well as cure the advances of this disease and technology and medication has changed over the years, that it has become a way of shortening the amount of therapy that is needed. Perhaps in the future individuals will commit resources, plan and implement interventions that are needed to help reduce the deaths that are caused by TB. References Centers for Disease Control and Prevention. (2009). The Centers for Law The Public Health. Retrieved from HYPERLINK http//www.cdc.gov/tb/programs/TBLawPolicyHandbook.pdf http//www.cdc.gov/tb/programs/TBLawPolicyHandbook.pdf Cobbelens, F.

This article examines the death ratios and accesses the clinical aspect of person that have been diagnose with tuberculosis (TB) and admitted to the ICU. The study was conducted, at the “medical ICU of a university hospital” from 2009 to 2014. The five-year study include the patient with positive skin and radiological manifestation of Tb, as well as those with positive cultures and excluded those who had received treatment a month earlier. The age, gender and overall health was also taken in to account. The study consisted of only 16 patients. By the end of the five-year study it was determined that all the contributed factors on mortality rate were drugs, related disease such as HIV, delayed treatment, and acute respiratory failure. Seven of the 16 patients died, four of the seven had pneumonia and of the eight patients with nosocomial and coinfection only one survived.

Grove et.al’s critical appraisal of a published study guideline will be utilized to assess the quality of the research studies. First, this writer will look at key components of each study, which typically includes: publication title, abstract, introduction, literature review, research methods used to address the research question(s) or hypothesis, statistical analysis used, results, and the researcher’s interpretation and conclusion or recommended use of results to inform future research or practice. During careful reading of the each study, this writer will try to:

Nations which have poor control of the AIDS epidemic also often have poor control of TB, effectively creating a ‘perfect storm’ of the prevalence of both diseases (Wells et al 2007). Individuals with AIDS are more susceptible to contracting TB and an environment where TB is prevalent can worsen the prognosis for individuals with TB. Developing world nations also have poor sanitation, longer wait times to see doctors due to problems of healthcare access, and other barriers which inhibit the needed speedy treatment of the disorder which can result in ineffective treatment and worsening of

According to the Centers for Disease Control and Prevention (CDC) in 2014, 9.6 million Americans were infected with the Tuberculosis (TB) disease. Over the years many programs and initiatives have been implemented to decrease the occurrences of TB disease in America. As long individuals are educated on the prevention of tuberculosis fatal complications can be prevented through early treatment. The purpose of this paper is to discuss the description of Tuberculosis and the demographic of interest, determinants of health and how determinants contribute to the development of Tuberculosis, epidemiologic triangle, role of the community health nurse, and the World Health Organization that works to address

The nurse welcomes Jeff to a private room at the end of the hall. According to hospital

TB is caused by a bacterial infection known as mycobacterium tuberculosis. If a patient is sick with TB is considered a disease. The infection is prevalent in the HIV population because approximately 13 million Americans are effected by the TB bacteria. It typically involves the lungs but can also affect the brain and other organ systems. The TB germ is airborne and can live in the air for several hours. Once an affected person coughs or sneezes another person breathes in the germ and becomes infected. A patient with TB and HIV/AIDS will have to take an antibiotics long term to battle the infection. They will have to go through two phases of medication. The initial phase consists of utilizing drugs such as isoniazid, pyrazinamide, rifamycin, and ethambutol for the first couple of months. Then the patient will enter into the continuation phase, during this phase the patient will take the isoniazid and rifamycin for approximately four months. HIV patient’s that are taking antiretroviral for the HIV will have to take the antibiotics longer. A person taking treatment for TB has to be careful because the antibiotic can cause liver damage. According to the CDC, roughly 6% of all TB cases are from patients with HIV or AIDS. In 1992 the United States had a dramatic increase in TB cases but has decreased ever since. Recently a group of researchers at John Hopkins

Tuberculosis (TB), a deadly contagious disease is among the three major infectious killers that causes high mortality and morbidity, worldwide.1 Tuberculosis infects one-third of the world's population with an estimated 8.7 million new cases and 1.4 million deaths every year (WHO, 2012)2. Tuberculosis prevention has become more complex due to increased resistance against different antibiotics including rifampicin.3

Tuberculosis is among the fatal diseases that are spread through the air. It’s contagious, meaning that it spreads from one infected individual to another, and at times it spreads very fast. In addition to being contagious, the disease is an opportunist infection as it takes advantage of those with weak defense mechanism, and especially the ones with terminal diseases like HIV and AIDS. Tuberculosis is therefore among the major concerns for the World Health Organization due to its contagious nature (World Health Organization 1).