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Asked Sep 14, 2019
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Complementation tests of distinct recessive mutants, 1 through 8, produce the data in the matrix below. A plus (+) indicates complementation, meaning the phenotype of the combined alleles is wild type, and a minus (-) indicates a failure to complement meaning that a mutant phenotype results. Assume that the missing mutant combinations would yield data consistent with the entries that are shown.

How many complementation groups are formed by these eight mutants? (Picture attached)

A) 2

B) 3

C) 4

D) 5

E) 6

1 2 3 4 5 6 7 i
1
+
2
3
4
+
5
+
7
8
+
Ln
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1 2 3 4 5 6 7 i 1 + 2 3 4 + 5 + 7 8 + Ln

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Expert Answer

Step 1

Complementation occurs when two strains of a organism with different homozygous recessive mutations produce the same mutant phenotype. The mutant phenotype produce offspring with the wild type phenotype when mated or crossed. Here, (+) denotes complementation and (-) denotes no complementation.

Step 2

In this matrix, mutants 1 and 4 complement each other while mutant 4 and 5 also complement each other. So, we can place 1,4 and 5 in the same complementation group. Similarly mutants 5 and 7 complement each other while mutants 6 ...

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