Gene A and B are 500,000 bp apart - the genes are either side of a recombination hot spot. Gene C and D are also 500,000 bp apart but the region containing genes C and D are not near a recombination hot spot. Would the map distance between A and B be the same as the map distance between C and D? Explain your answer.

Human Heredity: Principles and Issues (MindTap Course List)
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Author:Michael Cummings
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Chapter15: Genomes And Genomics
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Problem 2QP: Hemophilia and color blindness are both recessive conditions caused by genes on the X chromosome. To...
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Researchers have discovered that some regions of chromosomes are more likely than others to
cross
over, these areas of frequent crossing over are called "recombination hot spots".
Gene A and B are 500,000 bp apart - the genes are either side of a recombination hot spot.
Gene C and D are also 500,000 bp apart but the region containing genes C and D are not near a
recombination hot spot.
Would the map distance between A and B be the same as the map distance between C and D?
Explain your answer.
Transcribed Image Text:Researchers have discovered that some regions of chromosomes are more likely than others to cross over, these areas of frequent crossing over are called "recombination hot spots". Gene A and B are 500,000 bp apart - the genes are either side of a recombination hot spot. Gene C and D are also 500,000 bp apart but the region containing genes C and D are not near a recombination hot spot. Would the map distance between A and B be the same as the map distance between C and D? Explain your answer.
Expert Solution
Step 1

* Recombination hot spots are the regions of genome  where it can undergoes recombination in higher rates as compared to around.

* Thes recombination hotspots will help to get genomic diversity in the population.

* They are present in the multiple locations within genome.

* In humans these spots are absent.

*Many crossover would likely happen at this hotspot.

*A genetic map distance is not considered by looking physical distance.

*The probability of a crossover occurring along the distance between loci on a chromosome is the estimation of genetic map.

 

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